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Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re
The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-related genes; however, no systematic examination has yet been conducted. We used next-generation sequenc
Becoming alone in old age can be a decisive life event that brings major changes depending on various causes as health status, financial resources, family situation, and available welfare services. This article discusses the situation of older people in Sweden who have transitioned from a two-person to single-person household in recent years and what impact this might have on their everyday lives.
To combat climate change, different types of initiatives and policy instruments are required to support the development and dissemination of new energy efficient technologies. What type of policy instruments shall be used is, however, not pre-determined. To advance knowledge in how to design successful policy instruments, evaluations and deep-analyses are needed; this to better understand the role
Heckscher published in 1915 a book on the economics of World War I in Swedish. He analyzed the costs and the finances of war along similar lines as his contemporary Pigou (1916). Heckscher reached farther by making a distinction between the short and the long-run costs of war. He also provided a comprehensive theoretical and empirical analysis of the sources of funds for war finance, including a p
Four different thermal manikins (male and female shapes)in three different laboratories (UK, Sweden, and China) were used to determine the clothing thermal insulation values of 52 non-Western, mainly indoor clothing ensembles in order to expand the existing clothing database for use with ANSI/ASHRAE Standard 55-2013, Thermal Environmental Conditions for Human Occupancy (ASHRAE 2013a), ISO Standard
Small molecules increase direct neural conversion of human fibroblasts 1Scientific Reports | 6:38290 | DOI: 10.1038/srep38290 www.nature.com/scientificreports Small molecules increase direct neural conversion of human fibroblasts Ulrich Pfisterer1,2, Fredrik Ek3, Stefan Lang2,4, Shamit Soneji2,4, Roger Olsson3 & Malin Parmar1,2 The generation of human induced neurons (hiNs) via exogenous delivery
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_sci_rep.pdf - 2026-07-25
When selecting the least biased exposure surrogate, for example, the concentration of a biomarker in a urine sample, information on variability must be taken into consideration. We used mixed-effects models to estimate the variability and determinants of urinary cadmium (U-Cd) excretion using spot urine samples collected at six fixed times during 2 days about 1 week apart, from 24 healthy non-smok
Popular Abstract in Swedish På apoteket hittar vi den ena burken efter den andra med olika sorters smärtstillande medicin. Hur många av dessa är verkligen effektiva mot ihållande och svår smärta? Många receptbelagda läkemedel som lindrar smärta förändrar samtidigt vårt beteende, till exempel vår förmåga att fatta beslut. De kan dessutom också orsaka slöhet och onormal koordination. För att kunnaCurrent models of pain in conscious animals usually scores nocifensive responses. However, it is still unclear to what extent these responses are related to, for instance, the sensory discriminative or affective aspects of pain. This touches upon an intriguing question on how the nervous system processes nociceptive information in the conscious brain, a matter of which little is known. In order to
To study how prescription patterns concerning respiratory tract infections differ between interns, residents, younger general practitioners (GPs), older GPs and locums.
The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability
PET waste is the most visible environmental threat in the Maldives, a Small Island Developing State (SIDS). The thesis aims to propose the deposit refund system as a policy intervention, and evaluates the feasibility of introducing the system in the Maldives. In order to see how other SIDS have implemented the policy, the research uses policy evaluation framework to analyse the implementation mech
Under the growing influence of dominant discourses such as ecological modernisation and neo- liberalisation, proposed alternative conservation approaches focus more and more on efficiency. In the realm of biodiversity conservation, synthetic biology - the application of engineering to facilitate and accelerate the design or modification of genetic materials in living organisms – has emerged as an
Many citizens in Ranchi, Jharkhand, suffer from the consequences of contaminated drinking water. The city’s water governance system therefore urgently needs to find ways to bring safe drinking water to its people. Prevalent models in water governance however do not provide effective guidance for the necessary transition process. They lack heuristics that facilitate an in-depth understanding of con
Activation measures were implemented as a condition for social assistance in Sweden in the 1990s. Generally, the goal has been to promote the transition from welfare to work and to(re)integrate people dependent on social assistance into the labour market. Social assistance is regulated by the Social Services Act, which is a framework law that gives municipalities and individual social workers exte
Abstract: This thesis analyzes the distribution of profits to labor. The factor share distribution has attracted mounting attention from researchers in the last decades, as it has been identified as a central determining factor for economic inequality. However, how the factor share distribution has developed historically is debated. By analyzing the historical wage share for manufacturing workers
One of the target goals for sustainable development is the reduction of maternal mortality, which is a big health issue in some countries. Even if the research on maternal health care has come far and with the right expertise and supplies, almost all maternal deaths would be preventable. A working force to reduce the issues within maternal mortality in many countries are non-governmental organizat
This paper evaluates the impact of state visits on export flows and the specific role of the head of state based on the five Nordic countries: Denmark, Finland, Iceland, Norway, and Sweden. We construct a complete and comprehensive dataset containing all outgoing state visits from the Nordic countries between 1973 and 2022. Our main empirical strategy is to apply a difference-in differences (DiD)
