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Introduction: Consensus is lacking regarding the upper limit for a safe contraction frequency during labor. We aimed to assess the association between different contraction frequencies and acidemia at birth, and whether an association was affected by oxytocin augmentation, concomitant cardiotocography (CTG) classification, and stage of labor. Material and Methods: This is a case–control study base
OBJECTIVES: We assessed the prevalence of neurodevelopmental disabilities (NDDs; cognition, cerebral palsy, vision/hearing, epilepsy), attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), developmental coordination disorder (DCD), behavior problems, and multimorbidity in a national cohort of children born extremely preterm (EPT, <27-week gestation) to provide a comprehe
Introduction: The prevalence of overweight and obesity in children and adolescents continues to rise, and there is a lack of long-term follow-up to clarify health and well-being trajectories into adolescence and adulthood. This study investigated anthropometry and quality of life (QoL) trajectories in 7-14-year-old vulnerable children three years after attending a lifestyle camp. Methods: Vulnerab
The pulmonary route has emerged as a promising strategy for delivering protein therapeutics, particularly for patients suffering from respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary infections. This project investigated the effect of operating parameters of a laboratory spray dryer on the characteristics of powders composed of Bovine Serum Albumin
Dead wood is a key element in forest ecosystems and a wide range of organisms are dependent on this substrate for development and reproduction. Saproxylic beetles are important decomposers of dead wood and serve as food for many organisms. Due to the significant forestry-related decrease of dead wood in rural areas, many species of saproxylic beetles are considered threatened. Thus, other spaces h
Background: Eating disorders significantly impact physical health and have negative psychosocial consequences. The global burden of anorexia nervosa and bulimia nervosa among young females is estimated to account for 1.9 million disability-adjusted life years. Early identification of disordered eating attitudes is critical for preventing the progression to more severe forms of eating disorders; ho
Background: Several studies have investigated the association between metabolic syndrome (MetS) and physical activity (PA). However, further research is needed using objective measures of PA in free-living conditions, while also accounting for the time-variant nature of MetS. This study aimed to: (1) investigate the association between wearable device-measured step count and 5-year MetS incidence
AIMS/HYPOTHESIS: The aim of this work was to explore associations between type 1 diabetes progression from stages 1 or 2 to stage 3 and interacting ligand-receptor complexes of HLA class I (HLA-I) and KIR gene products.METHODS: Applying next-generation sequencing technology to genotype HLA-I genes (HLA-A, -B, -C) and KIR genes (KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5, KIR2DS1, KIR2DS2, KIR2DS3
Objective: To investigate the association of different aspects of cognitive impairment, depression and anxiety with walking difficulties in daily life in persons with mild PD.Background: Walking difficulties in daily life are common among persons with Parkinson’s disease (PD) and may cause falls and near falls, limitations in activity, restrictions in participation and decrease in quality of life.
Objectives: Pregnancy can influence immune control of Mycobacterium tuberculosis infection (MtbI). We recently reported an association between MtbI and pregnancy complications, particularly severe preeclampsia, in a registry-based cohort of women originating in tuberculosis-endemic countries screened for MtbI in Swedish antenatal care, implying a potential role of MtbI for the development of preec
BACKGROUND: Brief Admission by self-referral (BA) was implemented in 2018 in Swedish child and adolescent psychiatric (CAP) inpatient care. This intervention empowers adolescents to self-admit at their own request for brief periods to prevent self-harm and suicidal crisis. As BA enhances healthcare user autonomy, it is a timely intervention to consider with the emerging human rights discourse and
Background: The impact of air pollution and road traffic noise on depression remains inconclusive. This study examined long-term residential exposure to air pollutants and road traffic noise in relation to dispensed antidepressant medications. Methods: A cohort study was conducted using the Swedish Malmö Diet and Cancer Study, with the outcome defined as a first dispensed antidepressant (ATC: N06A
Introduction Asthma may increase the risk of comorbidities and systemic inflammation, but population data are scarce. This study aimed to compare comorbidities and systemic inflammation between those with and without current asthma and to identify characteristics linked to comorbidities and biomarkers. Methods In a cross-sectional analysis of 28 828 people aged 50–64 in the Swedish CArdioPulmonary
Background Suicide is more common among males and in older age, but the understanding of sex-specific and age-specific risk indicators is limited. Objective To describe the sex-specific and age-specific prevalence of 25 suicide risk indicators in the year preceding suicide and estimate their associations with suicide. Methods Register-based population-nested case-control study in Sweden, 2009–2021
Background Human papillomavirus (HPV) is associated with an increased risk for a variety of squamous cell carcinomas in the general population. The risk for subsequent squamous cell carcinomas in blood or marrow transplantation survivors that are potentially related to HPV (cervical, oropharyngeal, vulvar, vaginal, anal, and penile cancer; HPV-related squamous cell carcinomas) remains unknown. Met
BACKGROUND AND OBJECTIVES: Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by 3 core symptom complexes: parkinsonism, cerebellar syndrome, and dysautonomia. Recent Movement Disorder Society (MDS) criteria allow for the clinical diagnosis of MSA based solely on motor symptoms, without requiring dysautonomia. This study aimed to evaluate the frequency and disease trajecto
Objective: Foetal growth restriction (FGR) affects 10% of pregnancies, contributing to 30% of stillbirths. Current management of early-onset FGR (< 32 + 0 weeks' gestation) delivers the foetus before stillbirth or irreversible organ damage. The resulting preterm births create additional risks independent of FGR. We determined the economic cost associated with severe early-onset FGR. Design: Econom
https://biologi.blogg.lu.se/category/bdr/page/3/ - 2026-07-07
Objective: To describe-and compare the consumption of total fish (marine foods) and the fish sub-groups - white fish, fatty fish, very fatty fish, fish products and crustacea, in participants from the European Investigation into. Cancer and Nutrition (EPIC) study. Design: Cross-sectional analysis of dietary intake using a computerised standardised 24-hour recall interview. Crude means, means and s
Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this common malignancy. Findings from previous studies, however, have been inconsistent, and the nature of the associations is unclear.Methods: We conducted Mendelian randomization analyses to evalu
