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Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate with preeclampsia in the maternal genome at ZNF831/20q13 and FTO/16q12. These are previously established variants for blood pressure (BP) and the FTO variant has also been associat
A search is performed for a heavy particle decaying into different flavour dilepton pairs (eμ, eτ or μτ), using 3.2 fb- 1of proton–proton collision data at s=13 TeV collected in 2015 by the ATLAS detector at the Large Hadron Collider. No excess over the Standard Model prediction is observed. Limits at the 95 % credibility level are set on the mass of a Z′boson with lepton-flavour-violating couplin
Objective. To compare the effect of intraarticular injections of hyaluronan and placebo (vehicle, saline) in patients with knee pain on exertion and with joint cartilage abnormalities. Methods. Fifty-two patients with arthroscopically verified deep cartilage fissures and villus-like flakes in the symptomatic knee were randomly assigned to receive intraarticular injections of 2.5 ml of either hyalu
OBJECTIVES: Peripheral vascular disease (PVD) is an important limiting factor for healing in neuroischemic or ischemic diabetic foot ulcer. The purpose of this study was to identify factors related to healing in patients with diabetes with foot ulcers and severe PVD. METHODS: Patients with diabetes with a foot ulcer, consecutively presenting at a multidisciplinary foot center with a systolic toe p
The purpose of this work is to present results from an ongoing study on how the presence of surfaces influences the buckling properties of nanowires. This study is performed using molecular statics simulations where the interatomic interaction is modelled using an embedded atom potential (EAM) fitted to gold properties. The considered nanowires have rectangular cross sections with cross sectional
We identified clusters of atypical sensory functioning adults with ASC by hierarchical cluster analysis. A new scale for commonly self-reported sensory reactivity was used as a measure. In a low frequency group (n = 37), all subscale scores were relatively low, in particular atypical sensory/motor reactivity. In the intermediate group (n = 17) hyperreactivity, sensory interests and sensory/motor i
The Zumaya section, northern Spain, is a suitable candidate to define the Global Stratotype Section and Point for the base of the Selandian Stage (Palaeocene) because of its excellent accessibility, exposure and stratigraphic continuity. Uncertainties exist, however, with regard to the stratigraphic horizon where to place the Danian/Selandian (D/S) boundary. Five potential stratigraphic horizons (
Alkyl glycosides were synthesised from starch and alcohols using Aspergillus oryzae a-amylase as catalyst. In the degradation of starch by a-amylase, the alcohols competed with water as glycosyl acceptors. In the reaction with methanol, methyl maltoside and methyl maltotrioside were the main alcoholysis products. Conversion of 45 g/1 starch in 30% methanol resulted in a product mixture containing
UV-B treatment of thylakoid membranes or fractions derived from them accelerates the first rise (Fo---Fi phase) of variable fluorescence and slows down the second (Fi---Fm) rise. This can be observed for all membrane fractions but to different extents. The grana fraction is affected more by the UV-B treatment than are the intact thylakoids and the stroma lamella fraction. An exogenous electron acc
A control system for pneumatic variable valve actuation has been designed, implemented and tested in a single cylinder test engine with valve actuators provided by Cargine Engineering AB. The design goal for the valve control system was to achieve valve lifts between 2 and 12 mm over an engine speed interval of 300 to 2500 rpm. The control system was developed using LabView and implemented on the
