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The mass spectrometry (MS)-based analysis of free polysaccharides and glycans released from proteins, lipids and proteoglycans increasingly relies on databases and software. Here, we review progress in the bioinformatics analysis of protein-released N- and O-linked glycans (N- and O-glycomics) and propose an e-infrastructure to overcome current deficits in data and experimental transparency. This

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The Genographic Project is an international effort aimed at charting human migratory history. The project is nonprofit and nonmedical, and, through its Legacy Fund, supports locally led efforts to preserve indigenous and traditional cultures. Although the first phase of the project was focused on uniparentally inherited markers on the Y-chromosome and mitochondrial DNA (mtDNA), the current phase f

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Internet-of-things (IoT) systems consist of spatially distributed devices with services. Compared to desktop applications, IoT systems are always running and need to deal with unresponsive devices and weak connectivity. In this thesis, we examine the following question: How can we simplify the development of IoT systems? We begin to answer this question by proposing a domain-specific language (DSL

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Cucurbit crops have steadily increased in production over the last 50 years, particularly in Asia where pioneering technological advancements and genetic improvements have created new hybrid varieties. Generally, cucurbits are dependent on insect-pollination for fruit set and are popular species for pollination studies. This review systematically summarises pollination research conducted in the ma

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This document presents design considerations of a sample for accelerated thermal aging tests. The proposed specimen is a parallel wired solenoid that is evaluated by using an axi-symmetric 2D finite element (FE) model in Comsol multi-physics. The aim of the design model is visualizing an interior stress distribution of an idealized coil in order to interpret the physics-of-failure in a more comple

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Background and purpose — Targeted delivery of drugs is important to achieve efficient local concentrations and reduce systemic side effects. We hypothesized that locally implanted synthetic hydroxyapatite (HA) particles can act as a recruiting moiety for systemically administered drugs, leading to targeted drug accretion. Methods — Synthetic HA particles were implanted ectopically in a muscle pouc

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To demonstrate and support sustainability of large-scale infrastructure projects, life cycle assessment (LCA) has become a common tool used in the evaluation of environmental impact. However, LCA includes a number of phases, which are all associated with uncertainties. Decisions made without regard to these uncertainties may be suboptimal and/or misleading. The current paper discusses some importa

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In this thesis we extend several classical results about Calderón-Zygmund operators to spaces of vector-valued functions. We first obtain bounds for the norm of dyadic Haar shift operators using a Bellman function technique, and then apply the representation theorem to obtain corresponding results for general Calderón-Zygmund operators. We discuss several results for UMD space-valued Calderón-Zygm

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Particle methods such as the particle filter and particle smoothers have proven very useful for solving challenging nonlinear estimation problems in a wide variety of fields during the last decade. However, there are still very few existing tools available to support and assist researchers and engineers in applying the vast number of methods in this field to their own problems. This paper identifi

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Development of optical techniques in medical applications can be difficult due to limited access to realistic phantoms. Here a 3-D printed model based on CT-images of the thorax of an infant is developed and tested.

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Male marsh tits, Parus palustris, regularly feed their mates from the beginning of nest building until hatching. Over three periods (the 15 days preceding egg formation, egg formation/laying and incubation) the number of food passes by the male to the female increased significantly. There was a significant negative relationship between the frequency with which the male fed the female in the nest d

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Background We attempt to develop a relatively comprehensive structural model of risk factors for drug abuse (DA) in Swedish men that illustrates developmental and mediational processes. Methods We examined 20 risk factors for DA in 48,369 men undergoing conscription examinations in 1969–70 followed until 2011 when 2.34% (n = 1134) of them had DA ascertained in medical, criminal and pharmacy regist

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Objectives: The purpose of this presentation is to present the development, activities and achievements of the NOPHO/NOBOS Working Group on Ethics (WGE) 2008-2013. Methods: A joint working group on ethics, consisting of pediatric oncology nurses and physicians, was constituted during the NOPHO/NOBOS Annual Meeting in 2008. The intention was to create a Nordic competence group addressing ethical qu

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Desert vernacular architecture is a product of a sustainable building cycle. Desert local inhabitants inherited the traditional way of building from their ancestors developed and then transferred knowledge from one generation to another. This building and cultural cycle is about to disappear in many desert vernacular settlements of the world. Global ambitions and socio-economic developments are so

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While pure deliberation has still not been found online, the field of online deliberation research is blossoming. Born out of the “frustrations and possibilities” of the 1990s, a current theme in the field is to re-link deliberative theory with empirical political science. The aim of this systematic literature review is to sort out and examine important features of this development; to identify an