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BACKGROUND: Insulin-like growth factor 1 (IGF-1) is a mitogenic hormone involved in many processes such as growth, metabolism, angiogenesis and differentiation. After very preterm birth, energy demands increase while maternal supplies of nutrients and other factors are lost and the infant may become dependent on parenteral nutrition for weeks. Low postnatal IGF-1 concentrations in preterm infants
Der p 2 is one of the most important allergens from the house dust mite Dermatophagoides pteronyssinus Identification of human IgE Ab binding epitopes can be used for rational design of allergens with reduced IgE reactivity for therapy. Antigenic analysis of Der p 2 was performed by site-directed mutagenesis based on the x-ray crystal structure of the allergen in complex with a Fab from the murine
In response to global sustainability challenges, there are multiple public research andpolicy incentives being implemented to support a more sustainable energy system. These are aimed at advancing technology and innovation as well as guiding citizens tochange behaviour. But are those incentives accurately leading to a transition towards amore sustainable energy system and society?Evaluation of the
Most real-world applications of hypnosis involve a pair of actors: a hypnotist and a subject. Accordingly, most current models of hypnosis acknowledge the relevance of social factors in the development of the hypnotic response. Yet, psychophysiological research on hypnosis has been mostly restricted to techniques that are studying one individual, neglecting the complexity of hypnosis as a social p
In the present study, according to the recirculation concept, a new elimination structure for the geyser in a cryogenic pipe is proposed. An eccentric spacer plate is used to stimulate the recirculation inside the cryogenic pipe. The geyser-elimination effect of the proposed structure is then validated and the elimination physics is explored. It is found that the geyser is successfully eliminated
Diabetes is characterized by hyperglycaemia and entails many complications, including retinopathy and entrapment neuropathies, such as ulnar nerve entrapment (UNE) and carpal tunnel syndrome (CTS). Hyperglycaemia damages the nerves of the retina, as well as peripheral nerves. There is a correlation between entrapment neuropathies and retinopathy in patients with diabetes, but whether patients with
The number of scholarly blogs on the Web is increasing. In this article, a group of researchers are asked to describe the functions that their blogs serve for them as researchers. The results show that their blogging is motivated by the possibility to share knowledge, that the blog aids creativity, and that it provides a feeling of being connected in their work as researchers. In particular, the b
Epidemiological studies have shown a high prevalence of mental illness among the elderly. Clinical data however indicate both insufficient detection and treatment of illnesses. Suggested barriers to treatment include conceptions that mental health symptoms belong to normal aging and lack of competence among staff in elderly care in detecting mental illness. A Mental Health First Aid (MHFA) trainin
Background The popularity of tattoos has increased dramatically over the last few decades. Tattoo ink often contains carcinogenic chemicals, e.g., primary aromatic amines, polycyclic aromatic hydrocarbons, and metals. The tattooing process invokes an immunologic response that causes translocation of tattoo ink from the injection site. Deposition of tattoo pigment in lymph nodes has been confirmed
Following the idea originally proposed during the ESO-Workshop The Very Large Telescope in 2030, the concept of a high resolution spectrograph for the VLT has been further explored, both for the science and technological aspects. Such an instrument will fill a gap in capabilities amongst the landscape of future instrumentation planned for the next decade. Its key characteristic will be high spectr
On the basis of the dual variational formulation of a class of elliptic variational inequalities, a constitutive relation error is defined for the variational inequalities as an a posteriori error estimator, which is shown to guarantee strict upper bounds of the global energy-norm errors of kinematically admissible solutions. A numerical example is presented to validate the strictly bounding prope
Although COPD is a major disease worldwide there is a perplexing current uncertainty about the nature of this disease. COPI) is characterized at onset and prevalently by the involvement of the lungs and bronchi, but as the disease evolves abnormalities develop in other organs and systems and the question arises: what is the pathogenesis of these respiratory and systemic impairments? Are the altera
