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BACKGROUND: In early breast cancer, variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality. To examine this relationship, collaborative meta-analyses were undertaken, based on individual patient data, of the relevant randomised trials that began by 1995. METHODS: Information was available on 42,000 women in 78

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Background and Aims: Spontaneous type 1 diabetes (T1D) in the BioBreeding (BB) rat mimics human T1D as the rats experience weight loss, polydipsia, polyuria, ketoacidosis, onset during puberty and insulin-dependency within a day after diagnosis. Because the DP rat develops T1D spontaneously, it is a prime laboratory animal for dissecting the genetics of T1D susceptibility without the need for exte

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The HAVOSS (Handling Vulnerabilities in OSS) maturity model describes important processes for managing security vulnerabilities in OSS modules in developed products. So far, the model has not been evaluated in any real assessment process. Here we present a study where the model was evaluated by using it in assessments of processes for two product types in one organization. Each assessment was condThe HAVOSS (Handling Vulnerabilities in OSS) maturity model describes important processes for managing security vulnerabilities in OSS modules in developed products. So far, the model has not been evaluated in any real assessment process. Here we present a study where the model was evaluated by using it in assessments of processes for two product types in one organization. Each assessment was cond

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Importance: Information about how risk for bipolar disorder is transmitted across generations and how parental risk for bipolar disorder relates to their children's risk for schizophrenia and major depression is limited. Objective: To evaluate the sources of parent-offspring transmission of bipolar disorder and its familial cross-generational association with schizophrenia and major depression. De

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BACKGROUND: Chronic obstructive pulmonary disease (COPD) and asthma are common diseases with a heterogeneous distribution worldwide. Here, we present methods and disease and risk estimates for COPD and asthma from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2015 study. The GBD study provides annual updates on estimates of deaths, prevalence, and disability-adjusted life years (

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One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. An increasing number of cities have become significant tourism destinations. Cities also attract an increasingly diverse set of visitors, some of which could be called alternative tourists. The development of alternative tourism is related to decreasing relative costs One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. An increasing number of cities have become significant tourism destinations. Cities also attract an increasingly diverse set of visitors, some of which could be called alternative tourists. The development of alternative tourism is related to decreasing relative costs

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The hematopoietic stem cell (HSC) has and continues to be extensively investigated, and represents by far the most studied somatic stem cell. Development of various experimental technologies, including fluorescence activated cell sorting (FACS), have been crucial for research advancements within the hematopoietic field. However, utilization of flow cytometry techniques put high demands on study deThe hematopoietic stem cell (HSC) has and continues to be extensively investigated, and represents by far the most studied somatic stem cell. Development of various experimental technologies, including fluorescence activated cell sorting (FACS), have been crucial for research advancements within the hematopoietic field. However, utilization of flow cytometry techniques put high demands on study de

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According to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surprisAccording to the Swedish Enforcement Code a debtor is presumed to be the sole owner of movable property which is possessed jointly with a spouse or domestic partner. In my thesis, I investigate this statutory presumption of ownership from a family law perspective. The applicability of the statutory presumption as well as its legal repercussions are determined by family law. It is therefore surpris

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Spatial planning of Blue-Green Infrastructure (BGI) should ideally be based on well-evaluated and context specific solutions. One important obstacle to reach this goal relates to adequate provisioning of data to ensure good governance of BGI, i.e., appropriate planning, design, construction, and maintenance. This study explores the gap between data availability and implementation of BGI in urban p

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BACKGROUND: There are multiple options for the treatment of thumb carpometacarpal joint osteoarthritis (CMC1 OA), with evidence for pain relief and improved function. Although simple trapeziectomy has the lowest complication risk, tendon suspension of the first metacarpal and interposition is still the most commonly used surgical procedure in patients with CMC1 OA. Although there are several repor

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Light/dark cycles play an essential role in people's performance, mood and daily rhythm. This study aimed to evaluate an early prototype of a personalised home lighting system including body-worn loggers. A convenience sample (N = 28) wore the devices for 23 h in the field and were given a demonstration of the lighting system components. Participants reported on questionnaires their acceptance of Light/dark cycles play an essential role in people's performance, mood and daily rhythm. This study aimed to evaluate an early prototype of a personalised home lighting system including body-worn loggers. A convenience sample (N = 28) wore the devices for 23 h in the field and were given a demonstration of the lighting system components. Participants reported on questionnaires their acceptance of

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The present compilation thesis is divided into two sections, one for each of two separate methodological issues: reduction of random errors in mortality estimates and offsetting random variation related bias in data generated estimators of risk inequalities. Summary of section A In regard to the first issue a new family of survival functions is proposed. Its purpose is to provide valid and reliabl

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Aim of study: To elucidate the hemodynamic effects of pharmaceutical and medical interventions during pregnancy and childbirth on the mother.Introduction: Oxytocin, oxygen, and nitrous oxide are pharmaceuticals very commonly used in labor and delivery. These pharmaceuticals have known cardiovascular adverse effects. Some of these effects might be detrimental for the mother in case of major blood l

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This paper investigates social workers' perceptions of their relationships with clients across three Swedish different municipalities. By selecting three municipalities at varying stages of digitalization, the study facilitates a comparison of social workers' accounts. The comparison highlights differences in the descriptions of the relationship between social workers and clients, shedding light oThis paper investigates social workers' perceptions of their relationships with clients across three Swedish different municipalities. By selecting three municipalities at varying stages of digitalization, the study highlights differences in the descriptions of the relationship between social workers and clients, shedding light on whether, and if so, how, digital tools influence this relationship.

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Methodological considerations in practice-based research: lessons learned from research with a music school in SwedenThis is a presentation of a practice-based research project that has been carried out in collaboration between two course leaders from a music school in Sweden and one researcher between 2022 and 2023. The aim of the research project is to contribute to knowledge about pupil particiMethodological considerations in practice-based research: lessons learned from research with a music school in SwedenThis is a presentation of a practice-based research project that has been carried out in collaboration between two course leaders from a music school in Sweden and one researcher between 2022 and 2023. The aim of the research project is to contribute to knowledge about pupil partici

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Importance: Phase 3 trials of successful antiamyloid therapies in Alzheimer disease (AD) have demonstrated improved clinical efficacy in people with less severe disease. Plasma biomarkers will be essential for efficient screening of participants in future primary prevention clinical trials testing antiamyloid therapies in cognitively unimpaired (CU) individuals with initially low brain β-amyloid (

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This article offers a moral and logical critique of human rights minimalism, by which is meant an account that restricts human rights to a level of sufficiency above or beyond which inequalities have no moral relevance, and which makes duties prior to rights, such that rights are dependent on assumed or actual institutional capacities. The argument is that human rights minimalism fails by its own This article offers a moral and logical critique of human rights minimalism, by which is meant an account that restricts human rights to a level of sufficiency above or beyond which inequalities have no moral relevance, and which makes duties prior to rights, such that rights are dependent on assumed or actual institutional capacities. The argument is that human rights minimalism fails by its own

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Popular Abstract in Swedish Hydrogen holds a great promise as an efficient and clean future energy carrier due to its high energy density and lack of pollutant generation. Anaerobic degradation of organic substrates by heterotrophic microorganisms enables the production of hydrogen from a wide spectrum of agricultural feedstock and waste products. Using thermophiles in this process is preferable fHydrogen holds a great promise as an efficient and clean future energy carrier due to its high energy density and lack of pollutant generation. Anaerobic degradation of organic substrates by heterotrophic microorganisms enables the production of hydrogen from a wide spectrum of agricultural feedstock and waste products. Using thermophiles in this process is preferable for maximizing the substrate

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Differences in technological traditions we find between Neanderthals and anatomically modern humans has long been debated. It is important to discuss whether the differences in the handling of flint and other raw materials between the two populations . The use of raw materials are obviously directly related to the production of tools used to acquire food . Besides the quality of the material, also

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Title Insights on Brand Identity Creation of Start-ups in Business Incubators: An Exploratory Research Conducted in Sweden and Macedonia Course BUSN 39 Degree Project in Global Marketing, Spring 2013 Authors Aleksandar Joshevski and Lucas Noordhoorn Supervisor Magnus Lagnevik Keywords Brand identity creation, entrepreneurship, business incubators, start-up, Sweden, Macedonia Research Ques