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A hallmark of the afflicted nervous tissue in amyotrophic lateral sclerosis is the presence of protein aggregates which to a large extent contain the intermediate filament protein peripherin. Here we show that activation of protein kinase C (PKC) or overexpression of PKCe induces the aggregation of peripherin in cultured neuroblastoma cells with elevated amounts of peripherin. The formation of agg
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou
Title: Green is the new normal: An exploratory study of how slow fashion companies encourage normalization of sustainability initiatives in the retail store Date of seminar: June 5th 2019 Course name: BUSN39 Degree Project in Global Marketing Authors: Jennifer Phan & Xinyi Yao Supervisor: Andrea Lucarelli Key words: social normalization, social and personal norms, communication strategies
Growing concerns and sentiment about the negative environmental effects of the fashion industry pressure fashion companies to adopt eco-innovation and pursue more environmentally-sustainable product development. This study explores and examines the drivers of eco-innovation and environmentally-sustainable product development in small- to medium-sized fashion firms in Sweden and Denmark, with the p
In earlier studies it was revealed that thylakoid membranes inhibit activity of pancreatic lipase/colipase. More studies have shown that these membranes induce satiety hormone CCK and reduce hunger hormone of rats and human. Appethyl® used in this project is processed from spinach leaves in such a way that it reserves most amounts of thylakoid membranes. The results, in this project, shows that Ap
While the international community spends enormous amounts of money engaging in peacebuilding efforts, scholars are increasing questioning what effect this actually has on the development of peace. Despite extensive economic contributions to post-conflict societies with the hope of ensuring peace, little development on the ground has been recorded. This raises a question of why provision of economi
Pupil dilation is a reliable measure of cognitive load, and many studies have shown this effect in relation to various memory tasks. Interference from irrelevant memory traces encoded in the past lead to difficulty retrieving recent, sought after memory traces, and increased cognitive load. This investigation showed a significant decline in performance during buildup of interference and a signific
The purpose of this study is to investigate how peace and conflict within Nigeria can be understood. This is done by the application of a range of developmental indicators as well as theoretical variables drawn from the field of why insurgencies emerge. This study also includes the role of the Nigerian state in this dynamic. The applied method is a within-case comparison of three cases; the North
Freezing is a method used to preserve food for long periods of time by reducing the rate of naturally occurring reactions and growth of microorganisms. However, some irreversible quality changes, both physical and chemical, can take place during the freezing step. After being frozen, the products are stored until thawed and consumed. This thesis studies innovative freezing technologies to understa
Carbon offsetting is one strategy to tackle global climate change and decrease the level of greenhouse gases in the atmosphere. However, the strategy is debated and concerns are raised regarding negative impacts on the surrounding environment and biodiversity, the effectiveness and the morality of “buying the right to pollute”. The aim of this paper is to examine if ecological aspects are consider
“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san
The concern raised in this paper is whether the cone of diversification for EU to its low income trading partners has become more similar over time, as this would imply a risk for a Stolper- Samuelson effect. In order to assess this risk, the methodology in this paper is designed to capture any rising similarities of EU to its trading partners since a Stolper- Samuleson effect infers that the good
Physical activity may prevent anxiety, but the importance of exercise intensity, sex-specific mechanisms, and duration of the effects remains largely unknown. We used an observational study design to follow 395,369 individuals for up to 21 years to investigate if participation in an ultralong-distance cross-country ski race (Vasaloppet, up to 90 km) was associated with a lower risk of developing a
One of the main determinants of plasma homocysteine in healthy subjects is serum creatinine. In the present study, we therefore investigated the relation between plasma homocysteine concentration, serum creatinine and a new marker for glomerular filtration rate, plasma cystatin C concentration. Cystatin C reflects the glomerular filtration better than serum creatinine and is not related to the mus
In this paper, we present the case of a couple who refused to disclose the sex of their child to others, and some of the responses that this case prompted in the international media. We outline the ethical issues that this case raises, and we place it into the more general context of parental preferences regarding the gender (development) of their children and of the impact on children of parental
BACKGROUND: Infective endocarditis is associated with higher mortality in elderly patients, but the role of surgery in this group has not been fully evaluated. The aim of this study was to assess outcomes of left-sided infective endocarditis in elderly patients and to determine the influence of surgery on mortality in the elderly. METHODS AND RESULTS: A nationwide retrospective study was performed
Objective: Despite recommendations, assessment using spirometry or peak expiratory flow is insufficient in the clinical evaluation of suspected obstructive pulmonary disease. The aim was to investigate factors associated with performing spirometry or peak flow expiratory flow assessment. Methods: Randomly selected subjects from the general population aged 50–65 completed a respiratory questionnair
