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The purpose of this thesis is to discuss the reasoning behind the prominence of resilience building in Malawi’s development strategies, how resilience building is performed in Malawi, and what the potential and consequences of resilience in Malawi might be. In observations of a resilience building project and interviews with development practitioners, it was found that resilience had become promin
Objective The Captopril Prevention Project (CAPPP) was designed as a prospective intervention trial comparing the effect of a treatment based on the angiotensin-converting enzyme (ACE) inhibitor captopril with that of a conventional diuretic and/or beta-blocker-based therapy, in 10 985 hypertensive patients. There was no difference in the primary cardiovascular morbidity and mortality endpoint. A
The aim of this thesis was to identify the implications of the normative premises which are present in the NGO AgainstHTR-S, which works with assistance of victims of human trafficking for sexual purposes. This in order to outline how and why the NGO has the potential to adapt its “Attention Model” to the needs of the individual. In conjunction with a field work in Costa Rica, empirical data was g
A low eGFRcystatin C/eGFRcreatinine-ratio is characteristic of a group of serious kidney disorders called ‘Selective Glomerular Hypofiltration Syndromes’. This study examines if such a low ratio can also be used to evaluate the risk for women with hypertensive disorders in pregnancy to develop severe maternal morbidity. All women discharged from the perinatal ward at the Skåne University Hospital
Smallholder farmer-based rural social movements have been heralded as a promising source of political power with the potential to effectively promote sustainable trajectories of agricultural development in Sub-Saharan Africa and beyond. However, the very early stages of rural social movement building remain understudied, including under what conditions such nascent efforts are likely to lead to ef
Background: Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in the intensive care unit (ICU). Previous studies have suggested that blood group A increases the risk of developing ARDS following sepsis and major trauma. This study investigated the association between ABO and Rh blood groups and ARDS development and mortality in ARDS. Methods: Patients admitted to
Hexavalent chromium Cr(VI) is a human carcinogen, but the current exposure to Cr(VI) at Swedish workplaces is unknown.Recruitment of 113 workers with potential Cr(VI) exposure and 72 controls was combined with measurements of inhalable Cr(VI) (only exposed workers) and total Cr in urine and red blood cells (RBC), Bayesian analysis of occupational exposure limit (OEL) compliance was used, as well a
Peptide antibiotics are widespread in nature and, by providing a rapid first line of defense, may be key players in the innate immune system. Although epithelia are the main barriers shielding the internal environment from microorganisms, the role for peptide antibiotics in epithelial protection is unclear. We recently reported that the human cationic antimicrobial protein hCAP18, the precursor of
We have previously shown that exposure of DDT1 MF-2 smooth muscle cells to the agonist bradykinin (BK) resuits in a rapid B2 kinin receptor-mediated internalization of BK followed by degradation of the intracellular BK [Munoz, C. M., and Leeb-Lundberg, L. M. F. (1992) J. Biol. Chem. 267, 303-309]. Here, we show that BK internalization is paralleled by sequestration of the occupied B2 receptors. Se
This research investigated gender differences in misperceptions of gender differences in income. We hypothesized that men misperceive and underestimate the magnitude of gender income differences to a greater extent than women. Data was collected by means of a questionnaire, and respondents' (N = 314) perceptions of income differences were compared with official statistics. Results indicated that m
The semantic variant of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and progressive loss of semantic knowledge. Unlike many other forms of frontotemporal lobar degeneration (FTLD), svPPA has a highly consistent underlying pathology composed of TDP-43 (a regulator of RNA and DNA transcription metabolism). Previous genetic studies of svPPA are limite
Background: Older adults with pain have an increased risk of falling (odds ratio (OR) 1,7). Pain in Parkinson’s disease (PD) is more common than in older adults. The association between pain and falling in people with PD is poorly explored.Objective: To investigate the occurrence of pain in mild PD and its association with future falls/near fallsMethods. The study included 141 participants with PD
Class I major histocompatibility antigens are composed of a heavy chain that is noncovalently associated with β2-microglobulin (β2m). Most class I molecules are membrane bound, but mouse and rat cDNA clones and genes without a functional code for the transmembrane amino acids have been identified. The membrane-associated class I molecules are important in the control of cell-mediated cytotoxicity,
In September 1912, the Russian author Maxim Gorky wrote to the Paris-based Indian revolutionary Madame Cama and asked her to write an article on Indian women and their role in the Indian freedom struggle. Their correspondence highlights several issues: Cama’s central role among Indian and anticolonial nationalists from across the world in early twentieth-century Paris; the inspiration from the 190
Background: Patient safety gained public notoriety following the 1999 report of the Institute of Medicine: To Err is Human – Building a Safer Health System which summarized a culminated decades' worth of research that had so far been largely ignored. The aim of this study was to analyze the report's impact on patient safety research in anesthesiology.Methods: A bibliometric analysis was performed
OBJECTIVES: To examine physical activity level prior to pregnancy, during pregnancy and postpartum and investigate the association with depressive symptoms postpartum among women in Sweden.STUDY DESIGN: Retrospective observational study including 532 women on self-assessment of physical activity level before pregnancy, during pregnancy and postpartum, depressive symptoms postpartum as well as stre
