CFD modeling and comparison of bioreactor performance across scales at Alvotech
During bioreactor scale-up, unexpected failures become more prevalent due to the increase in volume. A comparison of mixing performance was thus made using computational modeling for two bioreactors at different scales. At the biopharmaceutical company Alvotech, bioreactors are used at different scales for producing biological medicines known as biosimilars. Bioreactors are vessels containing a m
