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Due to limited SNR the cerebral applications of the intravoxel incoherent motion (IVIM) concept have been sparse. MRI hardware developments have resulted in improved SNR and this may justify a reassessment of IVIM imaging for non-invasive quantification of the cerebral blood volume (CBV) as a first step towards determining the optimal field strength.
Predator avoidance behaviour costs time, energy and opportunities, and prey animals need to balance these costs with the risk of predation. The necessary decisions to strike this balance are often based on information that is inherently imperfect and incomplete due to the limited sensory capabilities of prey animals. Our knowledge, however, about how prey animals solve the challenging task of rest
Institutionen för Miljövenetskaplig Utbildning, Sölvegatan 37, 223 62 Lund http://www.miljovetenskap.lu.se/ MVEN06 - Miljöövervakning, 15p VT14 (Obs: alla tider med kvart!) Kurstid: - Kurschef: Johanna Alkan Olsson, tel: 072-741 79 90, email: johanna.alkan_olsson@cec.lu.se Lärare: Namn Email AKR Adam Kristensson Adam.Kristensson@nuclear.lu.se Projekthandledare (2 projekt) CAK Cecilia Akselsson Cec
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schemamven06_2014.pdf - 2026-06-28
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 31 v 40 - 2020. UNIVERSITETSGEMENSAMT Universitetet satsar på specialteam för att förebygga sexuella trakasserier efter Tellus-rapport* Vid ett webbinarium den 28 september presenterades resultaten från under
https://www.cec.lu.se/sites/cec.lu.se/files/2020-10/LU-gemensamt%20Mejlutskick%20Nr%2031-2020-v40.pdf - 2026-06-28
Background. Expression of the peptide hormones ghrelin and obestatin has previously been demonstrated in human mammary glands. However, the clinical implications of the expression of these peptides in breast cancer are unclear. The aim of this study was to investigate the potential clinical value of ghrelin and obestatin as breast cancer biomarkers. Methods. A tissue microarray containing breast c
microRNAs (miRNAs) are widespread regulators of gene expression, but little is known of their potential roles in congenital muscular dystrophy type 1A (MDC1A). MDC1A is a severe form of muscular dystrophy caused by mutations in the gene encoding laminin α2 chain. To gain insight into the pathophysiological roles of miRNAs associated with MDC1A pathology, laminin α2 chain-deficient mice were evalua
Myeloid-related proteins (MRPs) 8 and 14 are cytosolic proteins secreted from myeloid cells as proinflammatory mediators. Currently, the functional role of circulating extracellular MRP8/14 is unclear. Our present study identifies extracellular MRP8/14 as an autocrine player in the leukocyte adhesion cascade. We show that E-selectin-PSGL-1 interaction during neutrophil rolling triggers Mrp8/14 sec
This article discuss the consequences of the ambiguous view of children in the ethical guidelines – the ambitions to “give voice” while also “protect” – with a point of departure taken in the Swedish context, and in an actual research process of a project on children and care. It shows how the regulation of informed consent through the parent compromises the ideals of child-centred research; first
Real-world evaluation studies have shown that many patients with asthma remain symptomatic despite treatment with inhaled corticosteroids (ICSs). As conventional ICSs have poor access to the peripheral airways, the aim of the present paper was to study the relationship between peripheral airway inflammation and clinical control in allergic asthma. Consequently, bronchial and transbronchial biopsie
Mutation or epigenetic silencing of the transcription factor C/EBP alpha is observed in similar to 10% of patients with acute myeloid leukemia (AML). In both cases, a common global gene expression profile is observed, but downstream targets relevant for leukemogenesis are not known. Here, we identify Sox4 as a direct target of C/EBP alpha whereby its expression is inversely correlated with C/EBP a
BACKGROUND/OBJECTIVE: Bone remodeling is a critical process for skeletal health, and its dysregulation can lead to diseases like osteoporosis. While several Cyclin-Dependent Kinases (CDKs) are known to regulate bone metabolism, the function of CDK10 remains uncharacterized in this context. Human mutations in CDK10 cause the Al Kaissi syndrome, which involves severe skeletal defects, suggesting a
Circulating vitamin B6 levels have been found to be inversely associated with lung cancer. Most studies have focused on the B6 form pyridoxal 5′-phosphate (PLP), a direct biomarker influenced by inflammation and other factors. Using a functional B6 marker allows further investigation of the potential role of vitamin B6 status in the pathogenesis of lung cancer. We prospectively evaluated the assoc
KIT is a receptor tyrosine kinase (RTK) involved in several cellular processes such as regulation of proliferation, survival and differentiation of early hematopoietic cells, germ cells and melanocytes. Activation of KIT results in phosphorylation of tyrosine residues in the receptor, and recruitment of proteins that mediate downstream signaling and also modulate receptor signaling. Here we show t
Collagen type II (CII) is a cartilage-specific target of pathologic humoral autoimmune responses in rheumatoid arthritis as well as in the collagen-induced arthritis model. The aim of the present study is to investigate the critical amino acid residues conferring CII epitope specificity of the prototypic arthritogenic murine mAb CIIC1. A homology model of the CIIC1 single-chain antibody fragment (
This essay analyses conceptual metaphors in the Beatles’ song lyrics and observes how Lennon and McCartney’s use of metaphorical concepts evolved in the 1960’s. The study has an empirical and qualitative approach with quantitative elements, and employs the framework of Conceptual Metaphor Theory (CMT). Three specific RQs are studied in this thesis: (a) how the metaphors in Lennon and McCartney’s l
By using the method of framing analysis this bachelor’s thesis investigates how the debate of Scottish independence is framed by leaders representing the four largest political parties in Scotland. The material consists of speeches the politicians have held in the year of 2013, all speeches addressing the 2014 referendum and the issue of Scottish independence. By deconstructing the arguments commu
Recently, the single nucleotide polymorphism (SNP) identified as rs1260326, in the glucokinase regulatory protein (GCKR), was associated with hypertriglyceridemia in adults. Because accumulation of triglycerides in hepatocytes represents the hallmark of steatosis, we aimed to investigate whether this variant might be associated with fatty liver (hepatic fat content, HFF%). Moreover, because recent
There is a widespread belief that EU underperforms in the commercialization of publicly funded research and that the appropriate policy response is to transfer the ownership of intellectual property rights to Universities. This paper assesses the validity of these twin beliefs. In addressing the first, we limit ourselves to Sweden which still retains its "Teacher's Exemption" model. In spite of co
