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Following study seeks to categorize reform suggestions made by the Swedish Agency for Public Management in accordance to how they relate to two different models of public administration – one influenced by New Public Management and the other by neoweberian thought and perspectives. The study takes the form of a qualitative text analysis, where six reports authored by the agency in question are ana
Cationic liposome-DNA (CL-DNA) complexes, are regarded as promising materials for safe and efficient delivery of genes for therapeutical applications. In order to be used in vivo, these complexes may be coated with a hydrophilic polymer (e.g. polyethylene-glycol, PEG) that provides steric stabilization towards adhesion of proteins and removal by the immune system. In this work we study the influen
The Anselmian claim that God is that than which a greater cannot be thought in virtue of being ‘whatever it is better to be than not to be’ may be accused of incoherence or even unintelligibility. By proposing a non-relative but apparently meaningful analysis thereof, I attempt to defend it against such criticism. In particular, I argue that ‘whatever it is better to be than not to be’ can be plau
This is a master case about the latest Balenciaga's scandal regarding the 'Gift Shop' campaign 2022. This case was chosen by the authors as a starting point to investigate how far can and should the communication in the luxury field go. Is attention always positive? And when does it actually hurt the brand?
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL s
Objective. To analyse patients' self-reported reasons for not adhering to physical activity referrals (PARs). Design and setting. Data on 1358 patients who did not adhere to PARs were collected at 38 primary health care (PHC) centres in Sweden. Intervention. PHC providers issued formal physical activity prescriptions for home-based activities or referrals for facility-based activities. Subjects. O
Members of the TALE (Three-amino acid loop extension) family of atypical homeodomain-containing transcription factors are important downstream effectors of oncogenic fusion proteins involving the mixed lineage leukemia (MLL) gene. A well-characterized member of this protein family is MEIS1, which orchestrates a transcriptional program required for the maintenance of MLL-rearranged acute myeloid le
Aberrant dopaminergic signaling is a critical determinant in multiple psychiatric disorders, and in many disease states, dopamine receptor number is altered. Here we identify a molecular mechanism that selectively targets D2 receptors for degradation after their activation by dopamine. The degradative fate of D2 receptors is determined by an interaction with G protein coupled receptor-associated s
Chondromodulin I (chm-I), a type II transmembrane protein, is highly expressed in the avascular zones of cartilage but is downregulated in the hypertrophic region, which is invaded by blood vessels during enchondral ossification. In vitro and in vivo assays with the purified protein have shown chondrocyte-modulating and angiogenesis-inhibiting functions. To investigate chm-I function in vivo, we g
This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated w
The purpose of the study was to describe digital artists’ notions about their physical work environment in an organizational context. It is suggested that digital artists are creative professionals that use personal, creative imagination and skills to practice problem-solving by producing artistic artifacts. Based on four in-depth interviews and nine email interviews a qualitative research effort
The importance of supply chains and the dissemination of EMS concept trigged this research to explore the environmental supply chain requirements, the way these requirements are controlled and to reveal the potential interface with EMS. The focus of this research has been in supply chains in Sweden and Poland. Interviews were conducted with companies of various sectors and members of the consultan
The refugee status determination procedure involves complex issues of both law and fact. The process becomes even more complicated when facts arise that give indications on the possible applicability of article 1.F of the Refugee Convention. In this case the decision-maker has to decide on the one hand if the applicant qualifies for refugee status and on the other hand if there are serious reasons
Employee benefits can be seen as an HRM practice that has received increased attention among practitioners, while scholars’ interest in this theme has been moderate. The previous research focus has mostly been on how benefits contribute to organizational outcomes such as commitment, retention and attraction of employees. As opposed to this dominant view, this study sets out to explore employee ben
To investigate whether factors in the fetal or neonatal period influence the risk of later development of coeliac disease we conducted a population-based register study. The Swedish Medical Birth Register was linked with the Hospital Discharge Register and identified 3392 singleton infants born in the period 1987-97 who developed coeliac disease. Perinatal data for these children were compared wit
BACKGROUND: Pulmonary hypertension may result in significant morbidity and mortality after pediatric cardiac surgery. The objective of this study was to determine the incidence and outcome of severe pulmonary hypertension, defined as a ratio of pulmonary to systemic arterial pressure equal to or greater than 1.0, after cardiac surgery in children. METHODS: Data from all children younger than 18 ye
