Sökresultat

I denna uppsats härleds och testas en ny omviktningsalgoritm med vars hjälp det nativa tillståndet av aminosyresekvenser, bestående av 16 aminosyror, kan förutspås. Algoritmen används till att kartlägga de neutrala näten av α-helixes och β-sheets inom ett kontinuerligt proteinmodell. För att undersöka omviktningsalgoritmens potential för att förutsäga den termodynamiska stabiliteten av olika aminIn this thesis, a new reweighting algorithm for predicting the native conformations of amino acid sequences, consisting of 16 residues in a reduced representation continuous protein model, is derived and tested to map neutral nets of α-helices and β-sheets. For examining the potential of the reweighting algorithm for predicting the thermodynamic stability of amino acid sequences, it is applied to

Aims: Limited therapeutic options are available for the management of atrial fibrillation/flutter (AF/AFL) with concomitant heart failure (HF) with preserved (HFpEF) and mildly reduced ejection fraction (HFmrEF). Dronedarone reduces the risk of cardiovascular events in patients with AF, but sparse data are available examining its role in patients with AF complicated by HFpEF and HFmrEF. Methods an

Nudging has been discussed in the context of policy and public health, but not so much within healthcare. This scoping review aimed to assess the empirical evidence on how nudging techniques can be used to affect the behavior of healthcare professionals (HCPs) in clinical settings. A systematic database search was conducted for the period January 2010-December 2020 using the PRISMA extension for S

Abstract in NorweiganSammenfatning: Spørsmålet om identitet er alltid tilstedei akademiske og ikke-akad-emiskediskurser om religion og interreligiøse relasjoner: identitet som en kategori av noe som kan spigles fast, etableres ogopprettholdes ved hjelp av de"nisjonerog logikk; identitet som et spørsmål om noe stabilt og til og med rigid. Detteer viktig i overveielser omsynkretisme. I denne artikkeThe matter of identity is ever present in academic, and non-academic, discourses on religion and interreligious relations: identity as a category of something that can be nailed down, established and maintained with the help of definitions and logic; identity as a matter of something stable and even rigid. This is significant in deliberations regarding syncretism. In this paper, references are mad

A search for the decay to a pair of new particles of either the 125 GeV Higgs boson (h) or a second charge parity (CP)-even Higgs boson (H) is presented. The data set corresponds to an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV recorded by the ATLAS experiment at the LHC in 2012. The search was done in the context of the next-to-minimal supersymmetric standard model, i

In several extensions of the Standard Model, the top quark can decay into a bottom quark and a light charged Higgs boson H+, t -> bH(+), in addition to the Standard Model decay t -> bW. Since W bosons decay to the three lepton generations equally, while H+ may predominantly decay into tau nu, charged Higgs bosons can be searched for using the violation of lepton universality in top quark decays. T

Although documented from Estonia, Latvia, Sweden, eastern North America, and China, the Middle Ordovician (Darriwilian) positive delta C-13 excursion known as the MDICE has previously not been recognized with certainty in South America. The most promising region in South America for detailed Middle Ordovician carbon isotope research is the Precordillera of western Argentina, where there are many e

A search for direct pair production of supersymmetric top squarks ((t) over tilde (1)) is presented, assuming the (t) over tilde (1) decays into a top quark and the lightest supersymmetric particle, (chi) over tilde (0)(1), and that both top quarks decay to purely hadronic final states. A total of 16 (4) events are observed compared to a predicted standard model background of 13.5(-3.6)(+3.7) (4.4

The Archean basement in the northeastern part of the Kaapvaal craton is intruded by a large number of mafic dykes, defining three major dyke swarms, which collectively appear to fan out from the Bushveld Complex. Herein we present U-Pb baddeleyite ages for two of these dyke swarms, the northwest trending Badplaas Dyke Swarm and the east-west trending Rykoppies Dyke Swarm, and infer their correlati

Non-typeable Haemophilus influenzae (NTHi) is a Gram-negative human pathogen that causes a wide range of airway diseases. NTHi has a plethora of mechanisms to colonize while evading the host immune system for the establishment of infection. We previously showed that the outer membrane protein P5 contributes to bacterial serum resistance by the recruitment of complement regulators. Here, we report

A search for diphoton resonances in the mass range between 10 and 70 GeV with the ATLAS experiment at the Large Hadron Collider (LHC) is presented. The analysis is based on pp collision data corresponding to an integrated luminosity of 138 fb −1 at a centre-of-mass energy of 13 TeV recorded from 2015 to 2018. Previous searches for diphoton resonances at the LHC have explored masses down to 65 GeV,

A search is reported for excited τ-leptons and leptoquarks in events with two hadronically decaying τ-leptons and two or more jets. The search uses proton-proton (pp) collision data at s = 13 TeV recorded by the ATLAS experiment during the Run 2 of the Large Hadron Collider in 2015–2018. The total integrated luminosity is 139 fb −1. The excited τ-lepton is assumed to be produced and to decay via a

Cross-section measurements for a Z boson produced in association with high-transverse-momentum jets (p T ≥ 100 GeV) and decaying into a charged-lepton pair (e + e − , μ + μ −) are presented. The measurements are performed using proton–proton collisions at s = 13 TeV corresponding to an integrated luminosity of 139 fb −1 collected by the ATLAS experiment at the LHC. Measurements of angular correl

Purpose: Assess if cystatin C-derived measures of kidney function are associated with mortality in septic- and non-septic intensive care unit (ICU) patients. Methods: Data from adult patients staying >24 h in four ICUs in Sweden from November 2015–December 2018 included. Outcomes were mortality and need for renal replacement therapy (RRT) due to acute kidney injury. Associations between cystatin C

A search is presented for direct pair production of the stop, the supersymmetric partner of the top quark, in a decay through an Formula Presented-parity violating coupling to a charged lepton and a Formula Presented-quark. The dataset corresponds to an integrated luminosity of Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented collected between 2015 and

Objective: The European Society for Vascular Surgery (ESVS) has developed clinical practice guidelines for thecare of patients with diseases of the mesenteric and renal arteries and veins, in succession to the first 2017guidelines, with the aim of assisting physicians and patients in selecting the best management strategy.Methods: These guidelines are based on scientific evidence and expert opinio

Background: The increased prevalence of atopic diseases may be due to lifestyle changes affecting our exposure to microbes. We investigated the association between infections, fever, and atopic diseases in a large international birth cohort setting. Methods: 3842 children at genetic risk for type 1 diabetes were followed prospectively for the first 10 years for the occurrence of infections and ato

A search for charged-lepton-flavor violating Formula Presented (Formula Presented, Formula Presented) interactions is presented, considering both top-quark production and decay. The data analyzed correspond to Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented recorded with the ATLAS detector at the Large Hadron Collider. The analysis targets events conta

Objective: To study the impact of tumour necrosis factor-α inhibitor (TNFi) therapy on the use of non-steroidal anti inflammatory drugs (NSAIDs) in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) in Iceland. Method: This registry cohort study used data from the nationwide database on biologics in Iceland (ICEBIO) and the Icelandic Prescriptio

Grassroots innovations are seen as important contributors to sustainability transitions, however, given their dependence on place-specific conditions they face diffusion challenges. Responding to previously outlined gaps regarding conceptualisation and exploration of the spatiality of grassroots innovations, this paper introduces a conceptualisation of nomadic grassroots innovations. These are gra