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There are four peptidyl-proline bonds in the 64-residue protein chymotrypsin inhibitor 2 (CI2), all of which are in the trans conformation in the native structure. The isomerisation of one or more of these peptidyl-proline bonds to the cis conformation in the denatured state gives rise to heterogeneity, leading to both fast and slow-folding species. The refolding of the fast-folding species, which
A search has been performed for photons originating in the decay of a neutral long-lived particle, exploiting the capabilities of the ATLAS electromagnetic calorimeter to make precise measurements of the flight direction of photons, as well as the calorimeter's excellent time resolution. The search has been made in the diphoton plus missing transverse energy final state, using the full data sample
An inclusive search for anomalous production of two prompt, isolated muons with the same electric charge is presented. The search is performed in a data sample corresponding to 1.6 fb(-1) of integrated luminosity collected in 2011 at root s = 7 TeV with the ATLAS detector at the LHC. Muon pairs are selected by requiring two isolated muons of the same electric charge with p(T) > 20 GeV and vertical
Group G streptococcus (GGS) is a human bacterial pathogen expressing surface proteins FOG and protein G (PG) which interact with several host defense systems, including the complement and contact systems. Selected reaction monitoring mass spectrometry, electron microscopy, and protein binding assays were used to follow the amounts of FOG and PG intracellularly and on the bacterial surface during d
Abstract is not available.
The current fire testing and classification system and corresponding tests is mainly based on prescriptive building fire codes. This has certain limitations resulting in restricting the possible use of these tests for performance-based design within fire safety engineering (FSE). It also restricts innovation and cost-efficiency for companies supplying materials/components for buildings and transpo
Ecosystems can show sudden and persistent changes in state despite only incremental changes in drivers. Such critical transitions are difficult to predict, because the state of the system often shows little change before the transition. Early-warning indicators (EWIs) are hypothesized to signal the loss of system resilience and have been shown to precede critical transitions in theoretical models,
Objective/Background The objective was to analyze the long-term durability of intra-operatively placed Palmaz stents for type Ia endoleaks, and the evolution of aneurysm neck morphology. Methods This was a retrospective cohort study conducted at a tertiary referral centre. Patients treated between 1998 and 2012 were reviewed with regard to pre-, intra-, and post-operative data. Crude and relative
MAX IV is presently under construction at Lund, Sweden, and the first beam for the production of synchrotron radiation is expected to circulate in 2016. The whole set of 3 GeV ring beam pipes is coated with Ti-Zr-V Non Evaporable Getter (NEG) thin film in order to fulfil the average pressure requirement of 1×10-9 mbar, despite the compact magnet layout and the large aspect ratio of the vacuum cham
Haemophilia A is a congenital bleeding disorder characterised by recurrent haemorrhages into the major joints. Haemophilic arthropathy is a well-established outcome of recurrent joint bleeding; however, it is clear that multiple factors determine the extent and severity of its occurrence. We sought to identify genetic factors related to abnormalities in range of motion (ROM) in the knees, ankles a
Comprehensive approaches to predict performance of wood products are requested by international standards, and the first attempts have been made in the frame of European research projects. However, there is still an imminent need for a methodology to implement the durability and moisture performance of wood in an engineering design method and performance classification system. The aim of this stud
The main aim of the study was to optimize the interfacial presentation of a small antigen-a Tn antigen (N-acetylgalactosamine)-for binding to its analyte anti-Tn antibody. Three different methods for the interfacial display of a small glycan are compared here, including two methods based on the immobilization of the Tn antigen on a mixed self-assembled monolayer (SAM) (2D biosensor) and the third
The quest for effectiveness and results has become a top political priority in the international development sector during the last decade. One of the prevailing tools for effectiveness and goal fulfilment for development projects is the Logical Framework Approach (LFA). Implementing organisations, such as NGOs, are often obliged to use the LFA for planning, implementation and evaluation in order
Det finns många typer av säkerhetsstudier. En av dessa är en så kallad konfliktstudie. När man idag gör en traditionell konfliktstudie analyserar man trafiksäkerheten, oftast utifrån video-data. Det vill säga en observering av den verkliga situationen. En traditionell konfliktstudie har gjorts av Svensson & Ekblad, (2018) på en korsning vid Heleneholmsstigen/Ystadvägen i Malmö där man byggt omThere are many types of traffic studies. One of these is a so-called conflict study. Today when you do a traditional conflict study, you usually analyze traffic safety based on video data, which is an observation of the real situation. A traditional conflict study was made by Svensson & Ekblad, (2018) at a crossing at Heleneholmsstigen/Ystadvägen in Malmö, where a bicycle crossing was rebuilt.
The phenomenon of gender-based violence (GBV) and the magnitude it takes in Argentina is raising great concerns within the country, intergovernmental organisations and women’s movements. Since 2015 a women’s movement named Ni Una Menos was established to create visibility and fight for the eradication of gender-based violence in the country. Building upon the Integrative Ecological Framework, usin
Titel: “Jag tar aldrig av mig jobbhatten”, en kvalitativ studie om hur chefer uppfattar sin psykosociala ohälsa. Nivå: Kandidatuppsats i Service Management, VT 2019 Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Service Management Handledare: Johan Alvehus Syfte och frågeställning: Syftet med denna studie är att undersöka den organisatoriska- och sociala ohälsa som exis
Environmental conditions, dispersal lags, and interactions among species are major factors structuring communities through time and across space. Ecologists have emphasized the importance of biotic interactions in determining local patterns of species association. In contrast, abiotic limits, dispersal limitation, and historical factors have commonly been invoked to explain community structure pat
The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. The GIP-induced increase in osteopontin expression was inhibited by the NFAT (the transcription factor
