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Abstract Background Gender specific outcome for children with anorectal malformations (ARM) is rarely reported although it is important for medical care and in parent counseling. Purpose To assess bowel function according to the Krickenbeck system in relation to ARM-subtype, gender and age. Method All children born with ARM in 1998–2008 and referred to two centers in two different countries wer
Pneumococcal surface protein C (PspC) is a major virulence factor of Streptococcus pneumoniae and interferes with complement activity by binding complement factor H (fH). In this study, protection against experimental sepsis caused by pneumococci carrying different PspC variants was evaluated by immunisation with the fH-binding fragment of PspC. The mechanisms of protection mediated by antibodies
For decades, managers have analysed, planned and implemented long-term brand strategies based on customer mindset metrics (MSMs). Typically, such MSMs are customer satisfaction, liking, brand preference and Net Promoter Score (NPS). One of the core pillars, in brand management literature, is the assumed link between certain customer-based brand assets, often operationalized as MSMs, and future lon
The aim of the European project MASTER (MAnaging Speeds of Traffic on European Roads) is to produce information that can be cited in the preparation of national and EU decisions concerning speed management and standards for speed control equipment. For this purpose, the project seeks answers to three key questions:1) What are acceptable ranges of speeds?2) What are the key factors influencing dri
Type 1 diabetes (T1D) is an autoimmune disease associated with the destruction of pancreatic β cells and genetically linked to human leukocyte antigen (HLA) class II DR3-DQ2 and DR4-DQ8 haplotypes. The +49A/G polymorphism of the immunoregulatory cytotoxic T-lymphocyte antigen 4 (CTLA-4) gene is also associated with T1D. Genetic and environmental risk factors precede the onset of T1D, which is char
The first part of this paper discusses how Jesus is presented as a leader in the call narratives in the Gospel of Matthew (4.18–22). By making use of a biographical-narrative reading of Matthew, which takes the biographical genre seriously and pays attention to the narrative development of the story, and modern understanding of leadership, mainly by making use of transformational leadership theori
Aims: To investigate what NSE levels predict long-term neurological prognosis at 24, 48 and 72 hours after ROSC in a cohort of out-of-hospital cardiac arrest and to validate previously suggested NSE cut-offs, including the latest ERC guidelines (2021). Methods: Patients admitted to intensive care units in four hospitals in Southern Sweden between 2014–2018 were included. Blood samples were handled
One-stage method of polysulfone (PSf) membrane modification by the addition of polyacrylic acid (PAA, Mn = 250 kg·mol−1) to the coagulation bath during membrane preparation via non-solvent induced phase separation (NIPS) was proposed. The effect of PAA concentration on the membrane structure, hydrophilicity, zeta potential, separation performance and antifouling stability in ultrafiltration of lys
AIMS: This report reviews major laws, acts and regulations of social benefits and services for individuals with disabilities, focusing on cerebral palsy in the five Nordic countries. It summarizes the available benefits and services and the re-application process and provides comparative analyses among the countries.METHODS: Published reports, articles and relevant government and municipal website
To better understand the genetics of hearing loss, we performed a genome-wide association meta-analysis with 125,749 cases and 469,497 controls across five cohorts. We identified 53/c loci affecting hearing loss risk, including common coding variants in COL9A3 and TMPRSS3. Through exome sequencing of 108,415 cases and 329,581 controls, we observed rare coding associations with 11 Mendelian hearing
Climate change is recognized as one of the greatest environmental threats facing the world today. To tackle this problem, a protocol was adopted in Kyoto in 1997 which establishes legally binding commitments to developed countries to bring down the emissions of six major greenhouse gases by 5.2% compared to the year 1990. Three flexibility mechanisms have been provided to developed countries to ac
Den nuvarande ökningen av icke-statliga aktörer som bedriver kommersiell verksamhet i rymden har lett till juridiska frågor om bland annat ansvar. Är det nuvarande internationella rättsliga ramverket för yttre rymden tillräckligt etablerat för att hantera övergången från ett rättsområde som en gång dominerades av stater, till ett område som idag drivs av privata ekonomiska intressen? I denna uppThe important rise of non-state actors performing commercial activities in outer space has resulted in legal issues regarding inter alia responsibility. The question is whether the current international legal framework on outer space is sufficiently established to cope with a continuously shifting legal area once dominated by States to one today driven by private economic interests. This essay i
We present a detailed experimental and numerical study of the structural and dynamical properties of salt-free lysozyme solutions. In particular, by combining small-angle X-ray scattering (SAXS) data with neutron spin echo (NSE) and rheology experiments, we are able to identify that an arrest transition takes place at intermediate densities, driven by the slowing down of the cluster motion. Using
