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In this paper the choices of control variables and control structures are investigated for the Open Plate Reactor. Since the process design is very flexible, it allows many different control structures and variables and it may be non-trivial to find the most suitable choice. Analysis with the Relative Gain Array indicates that the flexible process configuration of the OPR enables a decentrali
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Despite the plethora of information on (S)-selective amine transaminases, the (R)-selective ones are still not well-studied; only a few structures are known to date, and their substrate scope is limited, apart from a few stellar works in the field. Herein, the structure ofLuminiphilus syltensis(R)-selective amine transaminase is elucidated to facilitate engineering towards variants active on bulki
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Aims: To evaluate the cost-effectiveness of bimekizumab, an inhibitor of IL-17F and IL-17A, against biologic and targeted synthetic disease-modifying antirheumatic drugs (DMARD) for psoriatic arthritis (PsA) from the Swedish healthcare system perspective. Materials and methods: A Markov model was developed to simulate the clinical pathway of biologic [b] DMARD-naïve or tumor necrosis factor inhibi
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This paper examines European narratives regarding border externalisation within the context of the European Trust Fund for Africa (EUTF). It seeks to understand how the EU shapes its discourse on African migration, recommends solutions, and evaluates outcomes. As the latest and most comprehensive instrument for externalising migration management, the EUTF offers abundant source material to compreh