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Shortcomings of current techniques used for the intracerebral transplantation of ventral mesencephalic dopamine neurons include low graft survival, high variability, considerable implantation trauma and suboptimal graft integration. In order to overcome these limitations, we have adopted a microtransplantation approach which allows precise and reproducible implantation of ventral mesencephalon cel
The results of a search for direct pair production of heavy top-quark partners in 4.7 fb(-1) of integrated luminosity from p p collisions at root s = 7 TeV collected by the ATLAS detector at the LHC are reported. Heavy top-quark partners decaying into a top quark and a neutral non-interacting particle are searched for in events with two leptons in the final state. No excess above the Standard Mode
Cation exchange chromatography has been routinely used for the quantification of monoclonal antibody (mAb) charge heterogeneity. A previously developed method utilizing pH gradients for the elution instead of salt gradients was validated according to current guidelines proposed by the ICH. The linearity, stability, accuracy, precision and the lower limit of quantification have been determined, usi
In this study, we investigated the interaction of fengycin, a lipopeptide produced by Bacillus subtilis, with lipid monolayers using the Langmuir trough technique in combination with Brewster angle rnicroscopy. Thermodynamic analyses were performed to get further information about the mixing behavior and the molecular interactions between the two components. The effect of fengycin on the structura
Enzymes adsorbed or deposited on porous support materials have been succesfully used as catalysts in organic media. However, the support must be chosen with great care. The support can affect the partitioning of substrates, products and water in the reaction mixture and thereby indirectly influence the catalytic properties of the enzyme. Furthermore, the support can influence both the enzyme kinet
Reduction of energy use in buildings is fundamental for sustainable development. A computer program for the prediction of energy use in buildings was assessed by comparisons with the energy performance of existing buildings. The program was then used to evaluate the energy saving characteristics of concrete such as air tightness and heat capacity. The impacts on global environmental aspects and li
This paper offers an analysis of a case of cooperation, and in particular cooperation problems, between independent performing arts organisations in the region of Skåne, Sweden. The cooperation in question flows from visions of the organisations, and linked regional commission to develop the infrastructure and networks of the independent performing arts in Skåne. The case gives evidence of the cha
Report of a trans-european research project that has taken place over two years (1999 – 2001) involving 15 partners from 10 EU countries, one EFTA and one non-EU country, and a European federation. On the basis of empirical and conceptual work the project proposes a common framework for education and training with a duration of six years. It is intended to be used to: Assess the adequacy of existi
The challenges for creating a greener economy and the institutional framework for sustainable development pass necessarily, or mostly, through cities, as they concentrate a large and growing part of the world’s economy and population, as well as decision-making power. With the processes of urbanization and rural-urban transformation, the economy in cities, especially in cities of developing countr
In the last decade 3D technologies have become a very effective means for managing and interpreting archaeological data. A better way to perceive, understand and communicate Cultural Heritage has been achieved through VR applications, which have enabled archaeologists both to make reconstructions of original landscapes and to put artifacts in their original context. Furthermore, the astonishing gr
Purpose: To evaluate against Monte-Carlo the performance of various dose calculations algorithms regarding lung turnout coverage in stereotactic body radiotherapy (SBRT) conditions. Materials and methods: Dose distributions in virtual lung phantoms have been calculated using four commercial Treatment Planning System (TPS) algorithms and one Monte Carlo (MC) system (EGSnrc). We compared the perform
For decades, accessibility to the physical housing environment for people with functional limitations has been of interest politically, professionally and for the users Guidelines and norms on accessible housing design have gradually been developed, however the built environment shows serious deficits when it comes to accessibility This study addresses development of a content valid cross Nordic v
Selective supercritical fluid extraction (SFE) at 40 degrees C, 400 bar and 60 min was used to selectively remove bioavailable PCBs from a naturally contaminated limnic sediment. The extraction decreased the sediment concentrations of the nine studied PCBs by 54% (on average). Chironomid larvae were thereafter cultured in pre-extracted sediment as well as in untreated sediment to study the differe
A novel process modeling tool to facilitate the study of how various process changes in the paper dryer section affect the mill-wide energy system has been developed. A model library with steady-state block models describing paper dryers, heat recovery equipment, and auxiliary systems on component level have been developed using the software Extend. Process models are then created from these block
Protein kinase C (PKC) isoforms have been reported to be targeted to the Golgi complex via their C1 domains. We have shown recently that the regulatory domain of PKCtheta induces apoptosis in neuroblastoma cells and that this effect is correlated to Golgi localization via the C1b domain. This study was designed to identify specific residues in the C1 domains that mediate Golgi localization. We dem
A method of correcting the asymmetry in the scattering of the tangential beam configuration in a rheo-small-angle neutron scattering experiment is proposed. The asymmetry of the scattering in the tangential beam configuration can be attributed to the difference in pathlength for neutrons that are scattered toward compared with those which are scattered away from the axis of rotation of the shear c
To assess the value of ECG-gating for the diagnosis of myocardial infarction using myocardial perfusion scintigraphy (MPS) and an artificial neural network. A total of 422 patients referred for MPS were studied using a one day Tc-99m-tetrofosmin protocol. Adenosine stress combined with submaximal dynamic exercise was used. The images were interpreted by one of three experienced clinicians and thes
