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Gambling disorder and problematic pornography use : Does co-occurrence influence treatment outcome?

Background and aims: Gambling disorder (GD) is a behavioral addiction often co-occurring with various mental health concerns, such as problematic pornography use (PPU). The specific impact of the co-occurrence of GD and PPU on treatment outcome remains underexplored. This study aimed to compare the treatment outcomes of individuals actively receiving treatment for GD (n = 172; 3.49% females), dist

Flat Gain, Single-Layer Annular Cavity Filtenna Based on TM and Quasi-TM Modes

This letter proposes a novel, low-cost, single-layer filtering antenna (filtenna) for wireless communications. The design consists of a compact circular substrate-integrated waveguide (SIW) cavity, a centrally offset metal post for feeding, and a slot radiator for efficient radiation. It is based on an SIW coaxial line and utilizes multiple TM and quasi-TM modes. Unlike filtennas that rely on inli

High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden

Objective. To search for primary hyperaldosteronism (PHA) among previously known hypertensive patients in primary care, using the aldosterone/renin ratio (ARR), and to evaluate clinical and biochemical characteristics in patients with high or normal ratio. Design. Patient survey study. Setting and subjects. The study population was recruited by written invitation among hypertensive patients in two

CHD7 mutation spectrum in 28 Swedish patients diagnosed with CHARGE syndrome

CHARGE syndrome is a disorder characterized by Coloboma, Heart defect, Atresia choanae, Retarded growth and/or development, Genital hypoplasia and Ear anomalies. Heterozygous mutations in the chromodomain helicase DNA-binding protein 7 (CHD7) gene have been identified in about 60% of individuals diagnosed with CHARGE syndrome. We performed a CHD7 mutation screening by direct exon sequencing in 28

Parents' experience of early discharge from hospital after birth in Sweden.

OBJECTIVE: to investigate the factors that influence the experience of mothers and fathers when they have chosen to return home, earlier than is the normal routine, following the birth of their baby. DESIGN: a qualitative study, using open interviews, was undertaken. The text of the transcripts was coded and categorised according to the grounded theory method using constant comparative analysis. S

Inhibition of angiotensin II-induced contraction by losartan in human coronary arteries

The in vitro effects of angiotensin II (Ang II) in human vessels are not well studied. The development of specific Ang II-receptor antagonists has made it possible to delineate more carefully the receptor mechanisms involved. The objective of this study was twofold: to investigate the effect of Ang II on human coronary arteries and to study the effects of angiotensin II type 1 receptor blockade wi

Implementation of endoscopic submucosal dissection for early colorectal neoplasms in Sweden.

Objectives. Endoscopic submucosal dissection (ESD) is an effective method for en bloc removal of large colorectal tumors in Japan, but this technique is not yet widely established in western countries. The purpose here was to report the experience of implementing colorectal ESD in Sweden. Methods. Twenty-nine patients with primarily nonmalignant and early colorectal neoplasms considered to be too

Quantification of growth and nutrient consumption of bacterial and fungal cultures in microfluidic microhabitat models

Understanding microbes in nature requires consideration of their microenvironment. Here, we present a protocol for quantifying biomass and nutrient degradation of bacterial and fungal cultures (Pseudomonas putida and Coprinopsis cinerea, respectively) in microfluidics. We describe steps for mask design and fabrication, master printing, polydimethylsiloxane chip fabrication, and chip inoculation an

Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk

Clonal hematopoiesis of indeterminate potential (CHIP) is associated with an increased risk of cardiovascular diseases (CVDs), putatively via inflammasome activation. We pursued an inflammatory gene modifier scan for CHIP-associated CVD risk among 424,651 UK Biobank participants. We identified CHIP using whole-exome sequencing data of blood DNA and modeled as a composite, considering all driver ge

Exploring The Effects Of Plastic-Free Packaging In The Pharmaceutical Industry

Today plastic packaging is used in a wide array of industries including the pharmaceutical industry. Nevertheless, the increasing amount of plastic waste from packaging is generating great amount of contaminants that do not only damage the environment, but as well the society and the economy as a whole. Whilst industries of fast consumer goods, such as the food and fashion industry enjoy vast rese

Bio-fouling reducers for improving the performance of an aerobic submerged membrane bioreactor treating palm oil mill effluent

A bench scale aerobic submerged membrane bioreactor (ASMBR) was used to treat diluted palm oil mill effluent (POME). For further improving the effluent quality and reduction of bio-fouling, powdered activated carbon (PAC) and zeolite were used as bio-fouling reducers (BM). We compared the performances of ASMBR without BFR (called BFR0) with ASMBR using BFR, namely 2 g/L PAC (BFR1), 4 g/L PAC (BFR2

Severe retinitis pigmentosa phenotype associated with novel CNGB1 variants

Purpose: To report a severe phenotype of retinitis pigmentosa associated with novel mutations in CNGB1. Observations: Six siblings, age range 50–75 years old, were examined using optical coherence tomography and fundus autofluorescene, electroretinogram testing, Goldman visual field testing, and genetic testing using next generation sequencing. In four affected siblings, two novel compound heteroz

Design and implementation of a 1024-point pipeline FFT processor

The design and implementation of a 1024-point pipeline FFT processor is presented. The architecture is based on a new form of FFT, the radix-22 algorithm. By exploiting the spatial regularity of the new algorithm, minimal requirement for both dominant components in VLSI implementation has been achieved: only 4 complex multipliers and 1024 complex-word data memory for the pipelined 1K FFT processor

How Vectoring in G.fast May Cause Neighborhood Wars

Emerging wireline transmission systems such as G.fast use bands up to around 200 MHz on short cables. A key enabler for achieving the aspired throughput of several hundred Mbit/s is joint processing of transmit signals in downstream direction as well as joint processing of receive signals in upstream direction through techniques referred to as vectoring. A new challenge in such systems are sudden

Raman spectroscopy in microfluidic chips reveals hyphal scale stress-associated metabolic responses in filamentous soil fungi

Understanding metabolic processes of soil fungi is essential for elucidating their ecological roles in biogeochemical cycles and responses to emergent environmental stressors. Here, we demonstrate the potential of using stable isotope probing Raman (SIP-Raman) microspectroscopy in microfluidics technology-based soil chips to trace glucose metabolism rates and stress responses in laboratory grown f

Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancer

An increasing incidence of testicular cancer has been reported from several western countries during the last decades. According to current hypothesis testicular cancer is initiated during the foetal period and exposure to endocrine disruptors such as some persistent organic pollutants has been of concern. We have previously reported the results for concentrations of polychlorinated biphenyls (PCB