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Dual-precision fixed-point arithmetic for low-power ray-triangle intersections

Ray-Triangle intersection is a fundamental computation in most ray tracing algorithms. The prohibitive cost of the ray-triangle test algorithms, however, limits the utilization of these algorithms in settings with low power budgets, such as mobile systems. In this work, we analyze the precision requirements for ray-triangle intersection and observe that for most of the rays a low-precision is suff

Suitable test concentration of cobalt and concomitant reactivity to nickel and chromium. A multicentre study from the Swedish Contact Dermatitis Research Group

Background: In Sweden, cobalt chloride 0.5% has been included in the baseline series since the mid-1980s. A recent study from Stockholm showed that cobalt chloride 1% petrolatum (pet.) was more suitable than 0.5%. Cobalt chloride at 1.0% has been patch tested for decades in many European countries and around the world. Objectives: To study the suitability of patch testing to cobalt 1.0% vs 0.5% an

Impact of LULCC on the emission of BVOCs during the 21st century

Land-use and land-cover change (LULCC) is one of the key drivers of anthropogenic climate change. In addition to greenhouse gases such as CO2 or CH4, LULCC affects also the emission of other carbon trace gases such as biogenic volatile organic compounds (BVOCs). We investigate the impact of changing LULCC on the emission of isoprene and monoterpenes during the 21st century using seven different la

Constraining the magnitude of the Chiral Magnetic Effect with Event Shape Engineering in Pb–Pb collisions at sNN=2.76 TeV

In ultrarelativistic heavy-ion collisions, the event-by-event variation of the elliptic flow v2 reflects fluctuations in the shape of the initial state of the system. This allows to select events with the same centrality but different initial geometry. This selection technique, Event Shape Engineering, has been used in the analysis of charge-dependent two- and three-particle correlations in Pb–Pb

Global RNA expression and DNA methylation patterns in primary anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC) is one of the most malignant tumors, with a median survival of only a few months. The tumorigenic processes of this disease have not yet been completely unraveled. Here, we report an mRNA expression and DNA methylation analysis of fourteen primary ATCs. ATCs clustered separately from normal thyroid tissue in unsupervised analyses, both by RNA expression and by DNA m

Sexual orientation, suicide ideation and suicide attempt : A population-based study

The aim is to investigate associations between sexual orientation and experience of suicide thoughts and suicide attempts. The 2012 public health survey in Scania, southern Sweden, is a cross-sectional population-based study including 28,029 participants aged 18–80 with 51.7% participation. The associations between sexual orientation and experience of suicide thoughts and attempts were investigate

Twenty-eight-day follow-up of patch test reactions to p-phenylenediamine and p-phenylenediamine dihydrochloride : A multicentre study on behalf of the European Environmental and Contact Dermatitis Research Group

Background: There is an ongoing discussion on whether routinely patch testing with p-phenylenediamine (PPD) 1.0% pet. is safe, owing to the risk of patch test sensitization. Late-appearing patch test reactions may reflect patch test sensitization, but may also be attributable to a low degree of pre-existing sensitization. Objectives: To follow the positive patch test reactions to PPD and its salt

SELF-PERCEIVED VOCAL HEALTH AND SOCIAL PARTICIPATION AMONG OLDER ADULTS

The aim of this study is to investigate the association between self-perceived voice problems and social participation among older adults (65-80 years). A complementary aim was to investigate the association between self-perceived voice problems and physical activity. Method Participants were recruited through social media and asked to complete an online questionnaire. In total, 152 individuals we

Non-volatile conductive gels made from deep eutectic solvents and oxidised cellulose nanofibrils

Ionogels offer huge potential for a number of applications including wearable electronics and soft sensors. However, their synthesis has been limited and often relies on non-renewable or non-biocompatible components. Here we present a novel two-component ionogel made using just deep eutectic solvents (DESs) and cellulose. DESs offer a non-volatile alternative to hydrogels with highly tuneable prop

Enhancement of phase change materials by nanoparticles to improve battery thermal management for autonomous underwater vehicles

Battery thermal management (BTM) plays a significant role in the safety and reliability of autonomous underwater vehicles (AUV) at higher speeds. In this study, a nanoparticle/phase change material (nano-PCM) composite is proposed for the BTM of an AUV. The effects of nanoparticle loading percentage (φ = 5, 10, and 15%) and nanoparticle filling range (α = 30, 60, 90, and 120°) on the battery tempe

Population-scale analysis of common and rare genetic variation associated with hearing loss in adults

To better understand the genetics of hearing loss, we performed a genome-wide association meta-analysis with 125,749 cases and 469,497 controls across five cohorts. We identified 53/c loci affecting hearing loss risk, including common coding variants in COL9A3 and TMPRSS3. Through exome sequencing of 108,415 cases and 329,581 controls, we observed rare coding associations with 11 Mendelian hearing

A novel membraneless β-glucan/O2 enzymatic fuel cell based on β-glucosidase (RmBgl3B)/pyranose dehydrogenase (AmPDH) co-immobilized onto buckypaper electrode

A novel membraneless β-glucan/O2 enzymatic fuel cell was developed by combining a bioanode based on buckypaper modified with co-immobilized Agaricus meleagris pyranose dehydrogenase (AmPDH) and Rhodothermus marinus β-glucosidase (RmBgl3B) (RmBgl3B-AmPDH/buckypaper) with a biocathode based on solid graphite modified with Myrothecium verrucaria bilirubin oxidase (MvBOx/graphite). AmPDH was connected

Similar hospital morbidity with the use of one or two internal thoracic arteries

The hospital morbidity and mortality of 100 patients operated with two internal thoracic arteries with or without additional vein grafts (BITA group) were compared with a matched group of 100 patients operated with one left internal thoracic artery (ITA) on the anterior descending artery with additional vein grafts (LITA control group). In each study group, 3% of the patients had diabetes mellitus

Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk

Clonal hematopoiesis of indeterminate potential (CHIP) is associated with an increased risk of cardiovascular diseases (CVDs), putatively via inflammasome activation. We pursued an inflammatory gene modifier scan for CHIP-associated CVD risk among 424,651 UK Biobank participants. We identified CHIP using whole-exome sequencing data of blood DNA and modeled as a composite, considering all driver ge

Role of Ligand-Driven Conformational Changes in Enzyme Catalysis : Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase

We have previously performed empirical valence bond calculations of the kinetic activation barriers, Δ G‡calc, for the deprotonation of complexes between TIM and the whole substrate glyceraldehyde-3-phosphate (GAP, Kulkarni et al. J. Am. Chem. Soc. 2017 , 139 , 10514 - 10525 ). We now extend this work to also study the deprotonation of the substrate pieces glycolaldehyde (GA) and GA·HPi [HPi = pho

Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan

We report the first large-scale retrospective cohort study on adolescent and young adult (AYA) polycythemia vera (PV) and essential thrombocythemia (ET) in Japan, a subgroup analysis using Japanese multicenter registry data (JSH-MPN-R18). This study included patients with PV (n = 31) or ET (n = 141) aged 20 to 39 years at the initial visit. Hemorrhage-free survival (HFS) was better in AYA ET than