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Associations between long-term exposure to low-level air pollution and risk of chronic kidney disease—findings from the Malmö Diet and Cancer cohort

Background: Associations between air pollution and chronic kidney disease (CKD) have been reported, but studies at low exposure levels and relevant exposure time windows are still warranted. This study investigated clinical CKD at low air pollution levels in the Swedish Malmö Diet and Cancer Cohort in different exposure time windows. Methods: This study included 30,396 individuals, aged 45–74 at e

Determinants of serum half-lives for linear and branched perfluoroalkyl substances after long-term high exposure-A study in Ronneby, Sweden

BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are persistent substances with surfactant and repellent properties. Municipal drinking water contaminated with PFAS had been distributed for decades to one third of households in Ronneby, Sweden. The source was firefighting foam used in a nearby airfield since the mid-1980s. Clean water was provided from December 16, 2013.AIMS: The purpose was

Breast cancer screening with digital breast tomosynthesis : comparison of different reading strategies implementing artificial intelligence

OBJECTIVES: Digital breast tomosynthesis (DBT) can detect more cancers than the current standard breast screening method, digital mammography (DM); however, it can substantially increase the reading workload and thus hinder implementation in screening. Artificial intelligence (AI) might be a solution. The aim of this study was to retrospectively test different ways of using AI in a screening workf

Observational constraints reduce model spread but not uncertainty in global wetland methane emission estimates

The recent rise in atmospheric methane (CH4) concentrations accelerates climate change and offsets mitigation efforts. Although wetlands are the largest natural CH4 source, estimates of global wetland CH4 emissions vary widely among approaches taken by bottom-up (BU) process-based biogeochemical models and top-down (TD) atmospheric inversion methods. Here, we integrate in situ measurements, multi-

Optically pure lactic acid production from lignocellulosic biomass

Lactic acid is a platform chemical that can be used for many applications. More recently, optically pure lactic acid—L- or D-lactic acid enantiomers—have been used for the polymerisation to poly-lactic acid (PLA). The possibility of tailoring the properties of this bioplastic by adjusting the ratio of each enantiomer might help to accelerate the substitution of petroleum-based plastics with bio-ba

Neuropsychiatric complications 3-4 years after stroke : A population-based study of fatigue, depression and cognition

Objectives To study the prevalence of and interplay between common neuropsychiatric sequelae 3-4 years after onset of first-ever stroke - specifically post-stroke fatigue (PSF), post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI). Design Population-based cohort study. Setting Catchment area of a Swedish University Hospital. Participants We recruited individuals with first-ever

Modelling wildfire and post-fire carbon budgets of a boreal forest under a changing climate

Understanding the dynamics of post-fire carbon recovery is critical for managing boreal forests under climate change. This study evaluates the LPJ-GUESS-BLAZE models’ performance in simulating vegetation structure, fire emissions, and post-fire carbon dynamics at the stand scale in a boreal forest in Sweden. Combining current climate and future scenarios (SSP1–2.6, SSP5–8.5), we investigated the i

Compulsory treatment of alcoholics, psychiatric comorbidity, psychological characteristics, coercive experiences and outcome

This thesis concerns involuntary treatment of alcoholism. Clients committed according to the Swedish Act on Care of Addicts in Certain Cases were treated in the same residential treatment setting as voluntarily admitted clients. After informed consent, 104 clients (73 men and 21 women of whom 56 were compulsorily committed and 47 voluntarily admitted) participated in a test-series, including asses

A stakeholder participated system science based sustainable development indicator framework

The growing interest in sustainable development indicators (SDI) has resulted in the development and application of various SDI frameworks in the past two decades. Identification and selection of “right” indicators with such frameworks are essential, in the sense that, it is the information from these indicators that will help policy and decision makers to better understand the efficiency, effecti

A thermostable alkaline protease from a new alkaliphilic Nesterenkonia sp.

This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. The organism grew at 37°C, pH 10, an

Plasma Membrane Proteomics and Functional Characterization & Expression Profiling of Plant Aquaporins

Popular Abstract in Swedish Många åtminstone i min generation kommer säkert ihåg att de under gymnasiets biologilektioner fick lära sig att vatten diffunderade fritt över cellens membran ? osmos och fri diffusion var ledorden. Jag vet inte hur läroböckerna är utformade idag, men efter att Nobelpriset i kemi år 2003 tilldelades Peter Agre för upptäckten av att aquaporiner fungerar som vattenkanalerIn order to identify integral and peripheral proteins associated with the plasma membrane (PM), highly purified Arabidopsis PMs were analyzed by mass spectrometry. In total, 238 putative PM proteins were identified, of which 114 were predicted to have transmembrane domains or to be PM-anchored. Identified proteins were involved in transport, signal transduction, membrane trafficking and stress res

En fiende till civilisationen : Manlighet, genusrelationer, sexualitet och rasstereotyper i svensk filmkultur under 1920-talet

The setting for this study is Swedish film culture of the 1920s, which has been studied with a focus on representations of masculinity and gender relations according to four themes: 1) children and youth 2) fatherhood and love 3) sexuality and popularity 4) ethnicity and racial stereotyping. The rise of new consumer culture in the first decades of the 20th century created turmoil between traditio

Methane emission bursts from permafrost environments during autumn freeze-in: New insights from ground-penetrating radar

Large amounts of methane (CH4) are known to be emitted from permafrost environments during the autumn freeze-in, but the specific soil conditions leading up to these bursts are unclear. Therefore, we used an ultrawide band ground-penetrating radar in Northeast Greenland in autumn 2009 to estimate the volumetric composition inside the soil through dielectric characterization from 200 to 3200 MHz. O

Diabetes mellitus and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

The current epidemiologic evidence suggests that men with type 2 diabetes mellitus may be at lower risk of developing prostate cancer, but little is known about its association with stage and grade of the disease. The association between self-reported diabetes mellitus at recruitment and risk of prostate cancer was examined in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Background High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are randomly assigned at meiosis, are independent of non-genetic confounding, and are unmodified by disease processes, mendelian randomisation can be used to test the hypothesis that the association of a plasma biomar

Activated protein C resistance in patients with peripheral vascular disease

PURPOSE: The frequency of activated protein C (APC) resistance, caused by factor V R506Q gene mutation and abnormal APC ratio, in patients with peripheral vascular diseases was analyzed. METHODS: All patients electively admitted to the vascular ward unit of our tertiary care academic medical center from January 1995 through October 1996 (n = 679) were prospectively analyzed using an APC-resistance

Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

Subjects with impaired glucose tolerance (IGT) are usually overweight and exhibit insulin resistance with a defective compensation of insulin secretion. In this study, we sought to establish the interrelation between insulin secretion and insulin sensitivity after oral glucose in non-obese subjects with IGT and we also examined this interrelation in relation to the 2 main incretins, glucagon-like

Miljöcertifiering av byggnader med Miljöbyggnad, GreenBuilding, BREEAM och LEED

Dagens miljöproblem måste lösas för att skona framtida generationer och miljön. Miljöcertifiering är en bit på vägen. Syftet med denna rapport är att redogöra för vad det innebär att miljöcertifiera en byggnad. Rapporten behandlar hur olika miljöcertifieringsmetoder fungerar och hur arbetsmetodiken för en certifiering ser ut. Eftersom det finns olika miljöcertifieringsmetoder är syftet också att gTitle: Environmental certification of buildings with Miljöbyggnad, Green Building, BREEAM and LEED - A review of the methods with comprehensive comparison Problem: Today's environmental problems must be solved in order to spare future generations and the environment. Environmental certification is a part of the solution. So what is the point with environmental certification and what reasons a

#MeToo, Men’s Sexual Violence against Women and the Chilling Effect of Defamation Lawsuits: A Feminist Critique of the Swedish Criminal Justice System

#MeToo became in 2017 a strong and successful movement in Sweden where women exercised their freedom of expression to question structural injustice and men’s sexual violence against women. The movement broke the silence and stigma about being victim of men’s sexual violence and helped fight impunity. However, some of the #MeToo women in Sweden who told their stories also pointed out their perpetra

Modelling the impact of climate change on future carbon dynamics of northern peatlands

Northern peatlands, spanning across vast regions of the northern hemisphere, are critical carbon reservoirs essential for global carbon cycling and climate regulation. Their dual role as long-term atmospheric carbon dioxide (CO2) sinks and the largest natural source of methane (CH4) in the northern hemisphere allows them to accumulate more carbon than they emit, helping to mitigate the rise in atm