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A holistic approach for planning care of patients with irritable bowel syndrome.

The aims of this study were to determine whether a registered nurse can collect information and plan a holistic and individual strategy for the treatment of patients with irritable bowel syndrome (IBS) and whether this approach can reduce these patients' health aspects. The referrals of 50 Swedish-speaking female patients aged between 18 and 65 years with the preliminary diagnosis of IBS were coll

alpha-Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

HAMLET (human -lactalbumin made lethal to tumor cells) is a complex of human -lactalbumin and oleic acid (C18:1:9 cis) that kills tumor cells by an apoptosis-like mechanism. Previous studies have shown that a conformational change is required to form HAMLET from -lactalbumin, and that a partially unfolded conformation is maintained in the HAMLET complex. This study examined if unfolding of -lactal

Har anmälan hjälpt barnet, eller snarare stjälpt det? En kvalitativ studie om förskollärares, BVC-sjuksköterskors och socialsekreterares syn på anmälningsskyldigheten och samverkan när det gäller barn som misstänks fara illa

The mandatory report legislation under Chapter 14, 1 § Social Services Act, imposes an obligation to report to social services if they suspect child maltreatment. The interest for our thesis topic was brought when we read articles and previous research showing that preschool teachers and well baby nurses do not always notify when they suspect child maltreatment. The aim of this study was to examin

Jämförelse av olika prognosticeringsmetoder - en fallstudie av Yaskawa Nordic AB

Companies always strives to acheive as eective inventory control as possible. At the same time, a suciently high delivery accuracy to satisfy the customer is pursued. One prerequisite for successfully accomplishing this is to anticipate customer demand in advance. An approximation of the demand in advance is called forecasting. Forecasting implies that dierent techniques are used to predict future

Har lagstiftaren mist koll på EU:s dataskyddskrav? - En analys av artikel 85 GDPR och dess konsekvenser i förhållande till den svenska regleringen av digitala söktjänster med utgivningsbevis

I Sverige finns ett antal företag som med stöd av offentlighetsprincipen samlar in personuppgifter ur allmänna handlingar och publicerar dessa i söktjänster på internet. Genom användning av söktjänsterna går det att skapa sig en utförlig bild av en viss individ. Söktjänsterna har i regel beviljats utgivningsbevis och omfattas därför av grundlagsskyddet i YGL. I Sverige har en vedertagen uppfattnin

Detection of insurance fraud using NLP and ML

Försäkringsbolag behöver identifiera och hantera en stor mängd potentiellt bedrägliga försäkringsanspråk från deras kunder. Därför har försäkringsbolag en rad system för att försöka identifiera vilka anspråk som är bedrägliga och vilka som inte är det. Med den senaste utvecklingen inom maskininlärning och särskilt inom området för språkbehandling (NLP) kan dessa tekniker eventuellt användas för atMachine-Learning can sometimes see things we as humans can not. In this thesis we evaluated three different Natural Language Procces-techniques: BERT, word2vec and linguistic analysis (UDPipe), on their performance in detecting insurance fraud based on transcribed audio from phone calls (referred to as audio data) and written text (referred to as text-form data), related to insurance claims. We al

Är det möjligt att utvärdera Kriminalvården? - En kritisk granskning ur ett nationalekonomiskt perspektiv

Syftet med denna uppsats var att undersöka huruvida ett nationalekonomiskt perspektiv, genom kostnads-intäktsanalys, kan bidra till att bredda diskussionen om Kriminalvården och dess effektiviseringsarbete. De mått som idag används för att beskriva fångvårdens effektivitet utgörs av bl.a. återfallsbrottslighet, påbörjade samt avslutade behandlingsprogram och antalet rymningar från anstalt. Ingen e

Free Foetal Haemoglobin in Severe Early-Onset Foetal Growth Restriction : A Prospective Multi-Centre Study

Objective: To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early-onset foetal growth restriction (FGR). Design, Setting and Population: A prospective study severe early-onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) < 3rd centile and <

Assimilating multi-site eddy-covariance data to calibrate the wetland CH4 emission module in a terrestrial ecosystem model

In this study, we use a data assimilation framework based on the adaptive Markov chain Monte Carlo (MCMC) algorithm to constrain process parameters in LPJ-GUESS model using CH4 eddy-covariance flux observations from 14 different natural boreal, temperate, and arctic wetlands. The objective is to derive a single set of calibrated parameter values. The calibrated parameter values are then used in th

Psychoeducation against depression, anxiety, alexithymia and fibromyalgia : a pilot study in primary care for patients on sick leave

Objectives: Feasibility testing of a psychoeducational method -The Affect School and Script Analyses (ASSA)–in a Swedish primary care setting. Exploring associations between psychological, and medically unexplained physical symptoms (MUPS). Design: Pilot study. Setting: Three Swedish primary care centers serving 20,000 people. Intervention: 8 weekly 2-hour sessions with a 5–7 participant group led

Clinical predictors of long-term survival in newly diagnosed transplant eligible multiple myeloma - an IMWG Research Project

PURPOSE: multiple myeloma is considered an incurable hematologic cancer but a subset of patients can achieve long-term remissions and survival. The present study examines the clinical features of long-term survival as it correlates to depth of disease response. PATIENTS & METHODS: this was a multi-institutional, international, retrospective analysis of high-dose melphalan-autologous stem cell

Capitation-Based Financing Hampers the Provision of Preventive Services in Primary Health Care

Mortality caused by non-communicable diseases has been extremely high in Hungary, which can largely be attributed to not performed preventive examinations (PEs) at the level of primary health care (PHC). Both structures and financial incentives are lacking, which could support the provision of legally defined PEs. A Model Programme was launched in Hungary in 2012 to adapt the recommendations for P

Analgesic antipyretic use among young children in the TEDDY study : No association with islet autoimmunity

Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o

The formation and design of the TRIAGE study-baseline data on 6005 consecutive patients admitted to hospital from the emergency department

Background Patient crowding in emergency departments (ED) is a common challenge and associated with worsened outcome for the patients. Previous studies on biomarkers in the ED setting has focused on identification of high risk patients, and and the ability to use biomarkers to identify low-risk patients has only been sparsely examined. The broader aims of the TRIAGE study are to develop methods t

Predictors of drug survival : A cohort study comparing anti-tumour necrosis factor agents using the Swedish inflammatory bowel disease quality register

Background: Whether long-term effectiveness differs between anti-tumour necrosis factor (anti-TNF) agents is unknown. Aims: To examine drug survival of first-line anti-TNF agents and identify predictors of discontinuation. To reduce channelling bias, we also compared drug survival of the second anti-TNF. Methods: Biologic-naïve patients (N = 955) recorded in the Swedish IBD Quality Register (SWIBR

Assessing the accuracy of [18F]PSMA-1007 PET/CT for primary staging of lymph node metastases in intermediate- and high-risk prostate cancer patients

Background: [18F]PSMA-1007 is a promising tracer for integrated positron emission tomography and computed tomography (PET/CT). Objective: Our aim was to assess the diagnostic accuracy of [18F]PSMA-1007 PET/CT for primary staging of lymph node metastasis before robotic-assisted laparoscopy (RALP) with extended lymph node dissection (ePLND). Design, Setting and Participants: The study was a retrospe

Pretreatment With P2Y12 Inhibitors in Patients With Chronic Coronary Syndrome Undergoing Percutaneous Coronary Intervention : A Report From the Swedish Coronary Angiography and Angioplasty Registry

BACKGROUND: In patients with chronic coronary syndrome undergoing percutaneous coronary intervention, the optimal timing of P2Y12 inhibitors' administration is uncertain. We compared pretreatment versus treatment in the catheterization laboratory (In-Cathlab) in a real-world population. METHODS: In Swedish Coronary Angiography and Angioplasty Registry, all patients with chronic coronary syndrome u