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Selective immunoglobulin A deficiency is the most common primary immunodeficiency disorder that is strongly overrepresented among patients with celiac disease (CD). IgG antibodies against tissue transglutaminase (tTG) and deamidated gliadin peptides (DGP) serve as serological markers for CD in IgA deficient individuals, although the diagnostic value remains uncertain. The aim of this study was to

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Popular Abstract in Swedish Spionen var under kalla kriget en gäckande gestalt som i egenskap av sin synliga osynlighet blev en orienteringspunkt för vardagliga fantasier. Han – för denna det kalla krigets emblematiska figur var oftast en han – blev i flera avseenden just en samtidens mittpunkt i vilken en tudelad världsbild synliggjordes. Mannen i mitten handlar om Spionen i svensk kallakrigskultThe aim of this thesis is to contribute to a broadening of perspectives on Cold War Sweden. It is a study not primarily of the explicit political events or debates, but of the everyday cultural narratives of the era. During the long 1950s, Swedish Cold War imagination was largely characterised by a determination to maintain total security in the response to the threats that loomed on all sides, an

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This paper presents a model for corporate social responsibility (CSR) created to integrate human rights issues in sustainable tourism, through public-private partnerships between the industry, non-governmental organisations (NGOs)and international governmental organisations (IGOs). The experience with the model in practice is described in a case study presenting a voluntary code of conduct adopted

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HAMLET (human alpha-lactalbumin made lethal to tumor cells) is a tumoricidal complex consisting of partially unfolded protein and fatty acid, and was first identified in casein fractions of human breast milk. The complex can be produced from its pure components through a modified chromatographic procedure where pre-applied oleic acid binds with partially-unfolded alpha-lactalbumin on the stationar

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The attitude of teachers towards students can vary substantially in relation to different factors, such as educational background, pedagogical training, teaching methods, etc. In this paper, we explore the impact of negative role-models on future teaching. In particular, past experiences of teachers as students as well as the contextual influence of other teachers on their future teaching has been

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I denna artikel analyseras muntligt gestaltade erfarenheter hos 27 överlevande efter kriget i nordvästra Bosnien under 1990-talet. Syftet är att dels beskriva hur de intervjuade framställer det sociala fenomenet «offerskap», dels analysera diskursiva mönster som medverkar i konstruktionen av kategorin «offer». Aktörernas anspråk på statusen «offer» skapar en konkurrens om offerrollen efter kriget.The aim of this article is to analyse verbally portrayed experiences of 27 survivors of the 1990’s war in northwestern Bosnia. My focus is on describing how the interviewees portray the social phenomenon of «victimhood» and on analysing the discursive patterns that contribute to construction of the category «victim». When, after the war, different actors claim this «victim» status, it sparks a com

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This paper provides a systematic review of scholarly literature concerning the enforcement of children’s rights in the classroom context and school management. The literature review is based on a systematic review methodology the authors developed drawing on the methods and guidelines used in the medical sciences over the last 15 years. Forty-two articles published between 1990 and 2014 were selec

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Popular Abstract in Swedish Ett bröstmjölksprotein som dödar tumörceller Denna avhandling beskriver den tumörcell- och bakteriedödande effekten av ett proteinkomplex från bröstmjölk. Proteinkomplexet, en veckningsvariant av humant alfa-laktalbumin, inducerar apoptos (programmerad celldöd) i tumörceller och visar sig ha liknande effekter även mot bakterier. Amning förser inte bara barnet med optiHuman milk contains a vast array of bioactive molecules, with nutritional and protective functions. This thesis describes the effects of a human milk protein complex, MAL, on tumour cells and bacteria. During our studies on the anti-adhesive properties of human milk we observed that a milk fraction killed tumour cells. The morphology of the cells indicated apoptotic cell death and this was verifie

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Popular Abstract in Swedish Streptococcus pyogenes (GAS) är en viktig sjukdomsframkallande bakterie som orsakar alltifrån lindriga infektioner som halsfluss (tonsillit) och svinkoppar (impetigo) till livshotande djupa infektioner som nekrotiserande fasceit eller ”Toxic shock syndrom”. På grund av det snabba sjukdomsförloppet i de livshotande infektionerna har streptokockerna fått beteckningen ”mörA distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and

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Solvents are commonly used in pharmaceutical and cosmetic formulations and sanitary products and cleansers. The uptake of solvent into the skin may change the molecular organization of skin lipids and proteins, which may in turn alter the protective skin barrier function. We herein examine the molecular effects of 10 different solvents on the outermost layer of skin, the stratum corneum (SC), usin

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Popular Abstract in Swedish En välfungerande andning med utbyte av syrgas och koldioxid mellan kroppen och omgivningen är en förutsättning för liv. För att detta gasutbyte ska fungera krävs bl. a. att ventilationen, dvs. in- och utflödet av luft i lungorna, står i balans med blodflödet genom lungorna. I lungorna tar blodet emot syrgas som behövs för att cellerna i kroppen ska fungera och samtidigtRespiration relies, among other things, on the balance between regional ventilation and perfusion in the lungs. There are many cardiopulmonary diseases, such as pulmonary embolism (PE), chronic obstructive pulmonary disease (COPD) and left heart failure (LHF), which can affect respiration negatively. The diagnosis of PE, COPD and LHF follows separate diagnostic pathways. However, the symptoms that

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Uppsatsens syfte har varit att kritiskt granska den svenska debatten kring DNA-analys för asylsökande barns rätt till familjeåterförening i Sverige och därmed se ifall principen om barnets bästa, definierat i svenska rättsakter, efterföljs. Genom den vägledande domen från Migrationsöverdomstolen den 18 januari 2012 fastslogs att DNA-analys kan användas för att styrka biologiskt släktskap med förälThe aim of this thesis has been to do a critical review on the Swedish debate concerning the use of DNA-tests to secure the rights of asylum-seeking children to be reunited with their families and if the principle of the best interests of the child is followed. The 18th of January 2012, in a precedent ruling, the Swedish Migration Court of Appeal concluded that DNA-test could be used to prove biol

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The aim of the thesis is to explore the relevance and the values related to physical books for students in the library room. The thesis addresses questions of how students use the physical books in the library room and if the physical books are perceived by the students as a source of formal and informal learning and serendipity. It will also try to find out what impact physical books have on stud

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Recent studies have identified a number of transcriptional regulators, including E2A, early B-cell factor 1 (EBF1), FOXO1, and paired box gene 5 (PAX5), that promote early B-cell development. However, how this ensemble of regulators mechanistically promotes B-cell fate remains poorly understood. Here we demonstrate that B-cell development in FOXO1-deficient mice is arrested in the common lymphoid

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The aim of this study was to examine support given to adult female victims of human trafficking for sexual purposes, by interviewing Swedish professionals within the organisation field. The focus was on how the support given in Sweden is adjusted to meet the women’s needs according to the professionals. We also examined the follow-up within other countries and their collaboration with Swedish orga

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Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri