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Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population, predominantly women(1-4). A number of susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes and mutations is yet to be identified(5-9). We previously reported a susceptibility locus (SLEB2) for Nordic multi-case

Flight is an expensive form of locomotion, but also offers the ability to travel great distances at relatively low cost. Birds have developed various adaptations for optimizing flight performance. The main aim of this thesis is to identify how morphological variables in birds affect aerodynamic drag and flight performance. To this end I studied the aerodynamic performance of a jackdaw (Corvus mone

Background Oxidative stress is implicated in both depression and anxiety, but it is currently unclear whether this relates to syndromal diagnoses or trans-diagnostic dimensional symptoms. We examined the relationship between oxidative stress and severity of depression and anxiety symptoms in individuals with Major Depressive Disorder (MDD). Methods Plasma oxidative stress markers F2-isoprostanes a

This study explores the control degree in success criteria operationalization. A literature review reveals that control degree relates to two patterns operationalizing success criteria: one directed to measurement and measure selection; the other directed to operationalization through the conceptualization of a relationship between a specific factor and project success. While in both patterns tigh

Ischemic stroke causes transient increase of neural stem and progenitor cell (NSPC) proliferation in the subventricular zone (SVZ), and migration of newly formed neuroblasts toward the damaged area where they mature to striatal neurons. The molecular mechanisms regulating this plastic response, probably involved in structural reorganization and functional recovery, are poorly understood. The adapt

This paper studies the nexus between income and wealth inequality, and the ecological footprint in the United States and France from 1962 to 2021. Based on theoretical considerations, we allow the relationship to vary over time. We find some support for income inequality affecting the ecological footprint in the United States and that the relationship has changed over time. We find no such result

Grocery retail is going through a rapid shift. Consumers now expect to be able to shop online or in stores, get orders delivered when and where they want, and preferably as quickly as possible. This development is called omnichannel and means grocery retailers must transform their logistics networks to meet consumers’ evolving expectations and demands. The omnichannel transformation includes, for