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We have evaluated the efficiency of two popular end-point methods to calculate ligand-binding free energies, LIE (linear interaction energy) and MM/GBSA (molecular mechanics with generalized Born surface-area solvation), i.e. the computational effort needed to obtain estimates of a similar precision. As a test case, we use the binding of seven biotin analogues to avidin. The energy terms used by M
untitled Copyright 2013 American Medical Association. All rights reserved. Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease Two Case Reports Zinovia Kefalopoulou, MD, PhD; Marios Politis, MD, PhD; Paola Piccini, MD, PhD, FRCP; Niccolo Mencacci, MD; Kailash Bhatia, MD, PhD; Marjan Jahanshahi, PhD; Håkan Widner, MD, PhD; Stig Rehncrona, MD, PhD; Patrik Brundin, MD, PhD;
https://www.wnc.lu.se/sites/wnc.lu.se/files/kefalopoulou_jama_neurol.pdf - 2026-05-28
Background: Despite optimal dopaminergic treatment most patients in moderate to advanced stages of Parkinson's disease (PD) experience progressively increasing disabilities, necessitating a shift from oral medication to device-aided therapies, including deep brain stimulation (DBS), intrajejunal levodopa-carbidopa infusion (IJLI), and continuous subcutaneous apomorphine infusion (CSAI). However, t
Objective: To describe the short- and long-term outcomes of infants with early-onset fetal growth restriction (FGR) and umbilical artery absent or reversed end-diastolic flow (AREDF), delivered before 30 weeks' gestation and managed proactively. Methods: This was a retrospective cohort study of fetuses delivered for fetal indication before 30 completed weeks' gestation that had early-onset FGR (de
V 1,28 Casa di Tofelanus Valens 1 The Swedish Pompeii Project, pompejiprojektet.se V 1,28 Casa di Tofelanus Valens Room b X 866 V 1,28 b, north wall V 1,28 Casa di Tofelanus Valens 2 The Swedish Pompeii Project, pompejiprojektet.se A marble tablet. It was found in Pompeii in a house on the west side of reg. V ins. 1 below the left wall of the atrium of the house whose door is the fifth from south,
https://www.pompejiprojektet.se/fileadmin/user_upload/pompejiprojektet/inscriptions/Casa_di_Tofelanus_Valens.pdf - 2026-05-04
https://www.lundobservatory.lu.se/Events - 2026-05-27
This article examines how intensive care staff navigated the emotional and temporal complexities of the COVID-19 pandemic, drawing on qualitative data from two Swedish ICUs. Rather than treating emotional responses as secondary reactions to crisis, the analysis shows that emotions were deeply embedded in professional feeling rules, organizational hierarchies, and the poly-temporal unfolding of the
Prefekten informerar • Nyheter på medarbetarfronten. Ann Kellner är sedan 1/4 anställd som vikarierande utbildningsadministratör. I dagarna an- ställdes Joakim Grina som affärsutvecklare kopplad till SoPact. Ann lånar inledningsvis Susanna Johansson rum på Bredgatan 13, vån. 3 medan Joakim har sin arbetsplats på Campus Helsingborg. Ni är båda mycket välkomna till Socialhögskolan! • Utlysning av vi
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/soch-infoblad-2018-04-13.pdf - 2026-05-28
AI@LU 2025 huvudrapport 17 November, 2025 AI@LU Mapping AI Education at Lund University (2025) Darcy Thompson (principal author) Mikael Sundström COMMISSIONED BY AILUND What’s the point of EduLab reports? EduLab reports are our way to keep track of core aspects of what we are working on. ese reports are intended to be short, snappy and to the point. Ideally, the briefing reports will provide some
Popular Abstract in English In an organism the DNA contains the entire biological information that is needed to be able to exist and function. Those segments, also known as DNA sequences are a genetic code, which is further packaged into units called genes. The entity of all genes is called genome. Today we know, that only a small proportion of genes encode for proteins, which are responsible for More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio
Boken Att dikta för livet, döden och evigheten har fokus på perioden 1500 till 1800 och på svensk tillfällesdiktning insatt i sitt nordeuropeiska sammanhang. Fältet är representativt och omfattande. Vi har lyckats intressera forskare inte bara från Sverige utan även från Danmark, Island, Finland, Estland, Ryssland och Tyskland att medverka med artiklar, vilket varit av avgörande vikt med tanke på
BackgroundThe Scandinavian Neurotrauma Committee (SNC) has recommended the use of serum S100B as a biomarker for mild low-risk Traumatic brain injuries (TBI). This study aimed to assess the adherence to the SNC guidelines in clinical practice and the diagnostic performance of S100B in patients with TBI. The aims of this study were to examine adherence to the SNC guideline and the diagnostic accura
https://www.wcmm.lu.se/whats/wcmm-friday-club - 2026-05-27
Background: AZD0837 is an investigational oral anticoagulant that is bio-converted to its active form, AR-H067637, a selective direct thrombin inhibitor. Objectives: The objectives of the present study were to investigate if there are any clinically relevant adverse effects of intravenous AZD0837 on cardiac conduction, refractoriness and repolarization, and to study its safety and tolerability. Me
