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Introduction: This work develops a compartmental model of F-18-choline in order to evaluate its biokinetics and so to describe the temporal variation of the radiopharmaceuticals' uptake in and clearance from organs and tissues. Methods: Ten patients were considered in this study. A commercially available tool for compartmental analysis (SAAM II) was used to model the values of activity concentrati
Accurate and precise chronologies are needed to evaluate the existence and effect of a post-depositional remanent magnetization lock-in process on sedimentary palaeomagnetic records. Here we present lock-in modelling results of two palaeomagnetic records from varved lake sediments (lakes Kalksjon and Gyltigesjon) in Sweden by using model predictions based on archaeomagnetic data. We used the C-14
The nanowire geometry offers significant advantages for exploiting the potential of III-Sb materials. Strain due to lattice mismatch is efficiently accommodated, and carrier confinement effects can be utilized in tunneling and quantum devices for which the III-Sb materials are of particular interest. It has however proven difficult to grow thin (below a few tens of nanometers), epitaxial III-Sb na
Apicidin is a potent histone deacetylase inhibitor (HDACI) that selectively binds to histone deacetylases (HDACs) class I and interferes with the deacetylation process, which results in modification of acetylation level of cellular proteins. The aim of the study was to investigate the potential time and dose dependent cytotoxicity of the test compound, Apicidin, in pancreatic cancer cells Capan-1
Previous research suggests that time-based working memory limits of 2-3 s constrain the integration of verbal information, and that speakers tend to parse sentences into prosodic phrases that do not extend beyond this time window. The present study used Event-Related Potentials (ERPs) to investigate how time-driven implicit prosodic phrasing influences the syntactic processing of embedded clauses.
Congenital muscular dystrophy with laminin α2 chain-deficiency (MDC1A) is one of the most severe forms of muscular disease and is characterized by severe muscle weakness and delayed motor milestones. The genetic basis of MDC1A is well-known, yet the secondary mechanisms ultimately leading to muscle degeneration and subsequent connective tissue infiltration are not fully understood. In order to obt
Epistemic uncertainty has been suggested to be fundamental to human experience. The authors of this paper believe that people need to exercise creativity in their conjectures, drawing upon knowledge and experience, in order to generate solutions to both instrumental and epistemic problems, and encourage higher orders of learning. Innovative methodologies are needed which can provide support for in
This paper is part of an ongoing research on the trajectory of rhetoric of political reforms in Bahrain during the past 10-years of reign by king Hamad bin Isa. Within less than two years of his reign, the king abandoned his wide ranging blueprints for political and institutional reforms designed to end to a decade-long civil unrest. I argue that the king continues to use, albeit more creatively,
Popular Abstract in Swedish Bostadsanpassning är en vanlig åtgärd inom kommunal service och rehabilitering. Avsikten är att ta bort fysiska miljöhinder i bostaden och den nära utemiljön för underlätta vardagliga aktiviteter och möjliggöra ett självständigt liv. Enligt svensk plan- och bygglagstiftning skall alla bostäder som byggs eller genomgår omfattande renoveringar vara tillgängliga och användHousing adaptation is a common intervention, in Sweden granted by municipal authorities, and performed in order to remove environmental barriers and enhance daily activities. In spite of increasing costs, efficient strategies for evaluation of the intervention are lacking. In this thesis, occupational therapy clients living in a south Swedish municipality and receiving housing adaptation grants we
Outcome questionnaires are increasingly being established as a validated mode of acquiring unbiased information on the results after health interventions. Using an assortment of questionnaires, distributed by mail to 27 372 and to a subgroup of 3 600 patients on file in the Swedish Knee Arthroplasty register (SKAR), relevant questionnaires were found to represent a feasable means of acquiring info
Popular Abstract in Swedish Delfiner och andra tandvalar har förmågan att ekolokalisera. Trots att dessa djur länge fascinerat människor genom historien var det först på 1950-talet som man lyckades bevisa att de faktiskt har denna förmåga. Det finns fortfarande många fundamentala frågor angående deras ekolokalisering som ännu inte besvarats, till stor del för att det har krävt alltför avancerad teToothed whales (Odontocetes) use echolocation to navigate and find food in dark or murky waters. A wide range of innovative studies has since the 1960:s been used to characterize their echolocation beam and map out their echolocation skills. In order to render high quality recordings of the sounds emitted by these animals, advanced measurement systems are required. There are still interesting env
The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops varies. Mathematical and computational analyses have suggested that loop complexity affects the overall flexibility of the oscillator, including
We have studied the epitaxial growth of an InP shell on various pure InAs core nanowire crystal structures by metal-organic vapor phase epitaxy. The InP shell is grown on wurtzite (WZ), zinc-blende (ZB), and {111}- and {110}-type faceted ZB twin-plane superlattice (TSL) structures by tuning the InP shell growth parameters and controlling the shell thickness. The growth results, particularly on the
Lignocellulosic biomass can be utilized to produce ethanol, a promising alternative energy source produced through fermentation of sugars. However, in order to achieve high sugar and ethanol yields, the lignocellulosic material must be pretreated before the enzymatic hydrolysis and fermentation. Dilute acid pretreatment, using SO2, is one of the most promising methods of pretreatment for softwood
Muscle atrophy, a significant characteristic of congenital muscular dystrophy with laminin α2 chain deficiency (also known as MDC1A), occurs by a change in the normal balance between protein synthesis and protein degradation. The ubiquitin-proteasome system plays a key role in protein degradation in skeletal muscle cells. In order to identify new targets for drug therapy against MDC1A, we have inv
The rate of constitutive isoprenoid emissions from plants is driven by plant emission capacity under specified environmental conditions (E-S, the emission factor) and by responsiveness of the emissions to instantaneous variations in environment. In models of isoprenoid emission, E-S has been often considered as intrinsic species-specific constant invariable in time and space. Here we analyze the v
Dug trenches in sediment-cored drumlins on the Småland peneplain, southern Sweden, occurring intermixed with rock-cored drumlins, revealed sedimentary successions and facies suggesting that the core sediments were primarily deposited proglacially, both in glaciolacustrine settings as delta-front and more distal deeper-water sediments, and as glaciofluvial braidplain sediments. From the relationshi
Background: The aim of this study was to determine whether relative qualitative and quantitative differences in protein expression could be related to smoke exposure or smoke-induced airway inflammation. We therefore explored and characterized the protein components found in bronchoalveolar lavage (BAL) fluid sampled from either lifelong smokers or never-smokers. Methods: BAL fluid samples obtaine
Aims: The indigenous flora of freshly chilled cold-smoked salmon just after the vacuum packaging, and the spoilage flora after storage, in vacuum package at 7 degrees C for 19 days, were to be investigated with two different sampling strategies. Methods and Results: Identification was performed using 16S rRNA sequencing of both isolated bacteria and bacterial DNA from tissue extract. The indigenou
