Sökresultat

Bakgrund: Till följd av att den globala konkurrensen tilltar, ökar komplexiteten, flexibiliteten och produktvariationen inom produktion. Detta leder till att förbättringsprojekt blir allt svårare att genomföra. Händelsestyrd simulering har i litteraturen blivit identifierat som ett verktyg med förmågan att lösa dessa utmaningar, men till följd av att komplexiteten i en produktion ökar, växer ocksåBackground: Following a growing global competition, complexity, flexibility and product variability of manufacturing systems are increasing. This has led to improvement projects becoming more difficult to carry out. Discrete event simulation (DES) has in literature been identified as having the capability to solve these challenges, but as complexity of a manufacturing system increases so does also

The PEGylation process is a covalent attachment between a protein (the pharmaceutical) and poly ethylene glycol (PEG) and since the beginning in 1977 PEGylation processes have been used to improve pharmaceuticals. PEGylation of a pharmaceutical achieves improved properties like greater solubility in water, longer residence time in vivo and extended shelf life. The PEGylation process is in general

Den klimatpåverkan, resursförbrukning och avfallsgenerering som byggbranschen står för idag är omfattande, till exempel står sektorn för 25–35 % av Europas avfall. Det råder en situation där resurseffektiviteten är låg och värdet av de råvaror som används inte tillvaratas. Förbrukningen av naturresurser är stor och möjligheterna att begränsa detta genom återbruk, där både resurser och inbyggd enerThe building industry is responsible for a substantial climate impact, resource consumption and waste generation. As an example, the sector produces 25-35 % of all the waste in Europe. Currently, the resource value is not captured as the resource efficiency is low. The consumption of natural resources is extensive and the opportunity to limit this through reuse, where both resources and the embodi

Denna uppsats har sin utgångspunkt i sakförsäkringar tecknade av konsumenter, det vill säga försäkringar som syftar till att i händelse av sakskada utge en ekonomisk kompensation som försäkringsersättning. Försäkringsersättningen ska motsvara den ekonomiska förlust som drabbat konsumenten till följd av sakskadan och på så sätt försätta konsumenten i samma ekonomiska tillstånd som vid tidpunkten fThis thesis looks into property insurances signed by consumers, i.e., insurances aimed at providing financial compensation in the event of damage on personal property. The compensation shall correspond to the financial loss suffered by the consumer as a result of the damage and thus put the consumer in the same financial condition as before the damage occurred. To calculate the financial loss, th

Produktionen av kemikalier på Perstorp AB genererar kontaminerat avloppsvatten som renas i industriparkens egna avloppsreningsverk innan de kan återanvändas till processen igen. Industriparken i Perstorp har villkor från avloppsreningsverket på hur mycket vatten som fabrikerna får släppa ut till avloppsreningsverket. Det finns fortfarande kapacitet kvar innan villkoret uppnås, men marginalerna serThe production of chemicals at Perstorp AB generates contaminated wastewater that is treated in the industrial park’s own sewage treatment plant before it can be reused in the process again. The industrial park has conditions from the sewage treatment plant on how much water the factories may discharge. There is capacity left before the condition is reached, but the margins look to decrease in the

Tillverkning av batterier är en mycket komplex process och det är en process som Saft AB är väl förtrogen med. För att kunna producera det antal batterier Saft AB gör måste de se till att alla led i produktionen håller en viss standard. Detta projekt hade i mål att utveckla ett användarcentrerat, interaktivt verktyg för Saft AB med förmågan att övervaka och analysera data som samlas in av sensorer

Den statliga lönegarantin är en skyddslagstiftning som ger arbetstagare rätt till ersättning om arbetsgivaren går i konkurs. I en granskande rapport från Riksrevisionen framkommer det att 6–9 % av utbetalt garantibelopp utgörs av misstänkt missbruk av lönegarantin. Uppsatsens syfte är att undersöka om de föreslagna åtgärderna i Riksrevisionens granskning kan förväntas minska missbruk av lönegarantThe earnings guarantee is a legislation designated to compensate employees for loss of salary if the employer is declared bankrupt. In an audit by the Swedish National Audit Organization (the Swedish NAO), it is estimated that 6–9 % of all earnings guarantee payments consist of misusage. The purpose of this article is to examine if the measures suggested by the Swedish NAO can be considered adequa

Aim: We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD-alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and evaluate preservation of beta cell function. Material and Methods: Etanercept Diamyd Combination Regimen is an open-labelled multi-centre study pilot trial whi

AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according

BACKGROUND The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of

Various Helicobacter species have been isolated from the stomach, intestinal tract and liver of a variety of mammalian and some avian species, and Helicobacter DNA has been detected in human bile and liver samples. An immunoblot assay was established to analyse serum antibody responses to non-gastric Helicobacter species in patients with autoimmune liver diseases, in comparison with healthy indivi

Widespread presence of toxic and persistent pollutants in the environment, even at low concentrations, causes risks of adverse effects to human health and the ecosystem. Biological methods for treatment of water streams and removal of persistent pollutants are of great interest due to their simplicity, low cost, and mild operational conditions without harmful by-products. The purpose of this resea

A new approach in isothermal heat conduction microcalorimetric studies of chemical and biological processes is explored. The general (non-specific) method of calorimetry is combined with more specific analytical methods of analysis to "multi-functional microcalorimetric process monitors". A microcalorimeter with specific analytical sensors placed in the reaction vessel for studies of processes in

Fouling is one the most important challenges to apply membrane technology on industrial scale in the food industry. Despite significant progress in understanding and preventing fouling and in developing appropriate membrane cleaning protocols, both fouling and cleaning remain key challenges in membrane plant operation in the food industry with a significant impact on membrane plants capital (CAPEX

Land ecosystems contribute to climate change mitigation by taking up approximately 30% of anthropogenically emitted carbon. However, estimates of the amount and distribution of carbon uptake across the world's ecosystems or biomes display great uncertainty. The latter hinders a full understanding of the mechanisms and drivers of land carbon uptake, and predictions of the future fate of the land ca

Den boreala regionen innehåller 40% av jordens kol (C) som lagras i vegetation och mark med sina skogar som står för nästan 30% av den terrestra C sänkan. Boreala skogar upplever några av de snabbaste hastigheterna för klimatuppvärmning och ökningar i brandaktivitet, vilket hotar att släppa ut stora mängder av deras C reserver till atmosfären. Även om klimat och skogsbränder har stark kontroll öveThe boreal region contains 40% of the earth’s carbon (C) that is stored in vegetation and soils with its forests accounting for almost 30% of the terrestrial C sink. Boreal forests are experiencing some of the most rapid rates of climatic warming and increases in fire activity, threatening to release large amounts of their dense C reserves to the atmosphere. While climate and wildfire place strong