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BACKGROUND/AIM: High morbidity and mortality rates, chronic course of disease and numerous clinical complications, make diabetes mellitus (DM) type 2 bear significant financial burden for healthcare system of Serbia. The aim of this study was to compare true disease-related expenses measured in the random sample of patients originating from the Central Serbia in 2007 and national estimate of total

Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings : A Systematic Review and Meta-Analysis

Objective: The aim of this systematic review and meta-analysis (SR-MA) was to identify signaling molecule profiles and blood-derived biomarkers in migraine and cluster headache (CH) patients. Background: Currently no migraine and CH valid biomarkers are available. Blood tests based on biomarker profiles have been used to gather information about the nervous system. Such tests have not yet been est

Costs of diabetes complications : hospital-based care and absence from work for 392,200 people with type 2 diabetes and matched control participants in Sweden

Aims/hypothesis: The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital

Getting the picture of home lighting: Adding participant photography to the interview

This paper draws attention to the potential benefits of using photographs in combination with interviews, that is to say photo elicitation. As defined by Harper (2002), photo elicitation is “based on the simple idea of inserting a photograph into a research interview” (p. 13). The photographs can be taken by the researcher or the participant to evoke comments. If participants are asked to produce

There is a need for new systemic sclerosis subset criteria. A content analytic approach

Objectives. Systemic sclerosis (SSc) is heterogenous. The objectives of this study were to evaluate the purpose, strengths and limitations of existing SSc subset criteria, and identify ideas among experts about subsets. Methods. We conducted semi-structured interviews with randomly sampled international SSc experts. The interview transcripts underwent an iterative process with text deconstructed t

Characterization of male breast cancer : Results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program

Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-year period. Methods: Patients with follow-up and tumor samples, treated between 1990 and 2010, in 93 centers/9 countries. Samples w

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes : A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol

Cross-species analysis of genic GC3 content and DNA methylation patterns

The GC content in the third codon position (GC(3)) exhibits a unimodal distribution in many plant and animal genomes. Interestingly, grasses and homeotherm vertebrates exhibit a unique bimodal distribution. High GC(3) was previously found to be associated with variable expression, higher frequency of upstream TATA boxes, and an increase of GC(3) from 5' to 3'. Moreover, GC(3)-rich genes are predom

New developments in madgraph/madevent

We here present some recent developments of MadGraph/MadEvent since the latest published version, 4.0. These developments include: Jet matching with Pythia parton showers for both Standard Model and Beyond the Standard Model processes, decay chain functionality, decay width calculation and decay simulation, process generation for the Grid, a package for calculation of quarkonium amplitudes, calcul

Interval and Consecutive Round Breast Cancer after Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Standard 2D Digital Mammography in BreastScreen Norway

Background: Screening that includes digital breast tomosynthesis (DBT) with two-dimensional (2D) synthetic mammography (SM) or standard 2D digital mammography (DM) results in detection of more breast cancers than does screening with DM alone. A decrease in interval breast cancer rates is anticipated but is not reported. Purpose: To compare rates and characteristics of (a) interval breast cancer in

On norovirus outbreaks and transmission in hospitals

Abstract Noroviruses are now the leading cause of gastroenteritis worldwide. Noroviruses are effectively transmitted due to a low infectious dose, viral shedding in high concentrations, environmental stability, and they induce only a limited immunity after infection. Especially, the norovirus variants of genotype II.4 (GII.4) have seemed greatly adapted for pandemic spread. The high infectivity of

Field Measurements for Verification of the Impact of Renovation and Maintenance Measures on Buildings : - regarding Energy Efficiency, Indoor Environment and Moisture Safety

Renovating the European building stock has for almost two decades been a matter of importance to the European Union. Reduction of energy use for existing buildings can be achieved through applying energy efficiency renovation measures. Besides this, there is quite a large renovation need in Sweden due to building materials and services reaching (or having passed) the end of their service life.IncoRenovating the European building stock has for almost two decades been a matter of importance to the European Union. Reduction of energy use for existing buildings can be achieved through applying energy efficiency renovation measures. Besides this, there is quite a large renovation need in Sweden due to building materials and services reaching (or having passed) the end of their service life.Inco

Towards classification criteria for early-stage knee osteoarthritis : A population-based study to enrich for progressors

Objective: To facilitate a greater likelihood of favorable response to new disease-modifying therapies, recruitment of patients at an earlier stage of their disease into clinical trials may be an attractive strategy. Hence, there is a need to develop widely accepted classification criteria for early-stage knee osteoarthritis (OA). We have proposed a set of classification criteria for early-stage k

Co-create Social Innovation - A mapping of Co-creation methods for Social Innovation

Background and issue of study: The global financial crisis, climate change, demographic changes, and rising inequality are some of the global trends that put pressure on public leaders and organizations, civil society organizations and corporations to shift to a social and environmental sustainable development. Social innovations are demanded to be both drivers of positive societal change and forc

FEM Modelling of Piled Raft Foundations in Two and Three Dimensions

In conventional design of pile foundations, all loads are taken by the piles, i.e. the contact pressure between the raft and the soil is neglected. In the last decades geotechnical engineers have started to take this pressure into account in design of pile foundation. Such a foundation, where the raft and the piles interact to transfer the loads to the ground, is in this dissertation called piled

Kulturen som får företagen att släppa kontrollen

Examensarbetets titel: Kulturen som får företagen att släppa kontrollen - En studie i syfte att utforska sambandet mellan företagskultur och kontrollkostnader. Seminariedatum: 2018-01-11 Ämne/kurs: FEKH19 Examensuppsats Kandidatnivå, Företagsekonomi, 15 hp Författare: Nathalie Krumm, Elin Söderbergh, Sara Thulesius & Emma Åkesson Handledare: Merle Jacob Nyckelord: Företagskultur, värderingar, Title: The culture that make companies loosen their control - A study conducted to explore the possible relationship between corporate culture and control costs. Seminar date: 2018-01-11 Course: FEKH19, Bachelor Thesis, Business Administration, 15 University Credit Points (ECTS) Authors: Nathalie Krumm, Elin Söderbergh, Sara Thulesius & Emma Åkesson Advisor: Merle Jacob Keywords: corporate cul

Low friction sliding door seal

This is a project in product development made for ASSA ABLOY Entrance Systems which is a manufacturer of sliding doors among other products. The objective of this project is to come up with a solution which offers an improved air sealing capability for a set of sliding doors all while the friction remains either the same or lower compared to before. The development process began with collecting in

Organizational Politicking: An Empirical Study on its Application to Communication Practitioners

Organizational politicking (OP), otherwise known as workplace politics has for many decades been a deeply subverted topic in the management literature due to its widely negative credo. This study aims to investigate OP and its uncharted utilization within the communication profession drawing upon the empirical foundation of 15 qualitative in-depth interviews with communication practitioners in var

Mellanchefen – skavsårsplåster på förändringsrundan

Denna fallstudie syftar till att utvinna fördjupad kunskap om mellanchefens komplexa och mångtydiga roll som meningsskapare och meningsgivare under en digitaliseringsförändring. Tidigare forskning har nämligen betonat mellanchefens roll som avgörande under en förändringsprocess. Detta eftersom mellancheferna innehar en roll som meningsskapare när de omvandlar övergripande organisationsinformation The purpose of this case study is to gain a deepened knowledge about the middle manager's complex and ambiguous role as sensemakers and sensegivers during a digital change. Former research has emphasized the middle manager’s role as crucial during a process of change. This because the middle managers hold a role as sensemakers when they convert the organizational information to their own units