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Background: There is little agreement on clinically useful criteria for identifying real-world responders to biologic treatments for asthma. Objective: To investigate the impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in adults with severe asthma. Methods: This was a longitudinal, cohort study across 22 countries participating in the International Sever
Popular Abstract in English Every level of human existence is affected by forced migration. It affects the central aspects of our outer and inner life. However, scientific research focused on the inner life of forced migrants, in particular the one regarding the impacts of forced migration on the most significant values that we hold in life, is often marginalized in forced migration studies. In anUntil recently studies regarding the pathological aspects of refugee experiences have led the psychology field of forced migration, giving little space to positive factors like the resilience and well-being of individuals faced with these adversities. This doctoral thesis emphasizes good health rather than disease and aims at deepening the understanding of resilience and health as opposed to the d
Lubyanka- IIIrd Floor. Memoirs of the KGB-chairman Vladimir Semichastny This book (published in Czech language in 1998) gives the reader a chance to follow the development of those times as seen by one of the most powerful men of his days - the highest predecessor of the Commitee for State Security at the Council of Ministers of the USSR (better known under the abbreviation KGB). Considering his
Inflammatory responses play a vital role at different stages of colorectal carcinogenesis. C-type lectins mediate inflammatory/immune responses and participate in immune escape of pathogens and tumors. Our study aimed to evaluate the correlation between polymorphisms in three C-type lectin genes, CD209, MBL2 and REG4, and colorectal cancer (CRC) risk and clinical outcome. We genotyped 15 potential
The study aims to establish the effectiveness of the Danish destination certification scheme – Destination 21. In order to accomplish this, an analytical framework, based upon current tourism and development theory, was constructed against which the scheme was tested. The analytical framework consists from three analyses examining the schemes framework, substance and applicability. It was found th
The increased number of companies supplying knowledge intensive business services (KIBS) has caused a highly competitive market during the recent decade, where actors on the market struggle to gain competitive advantage and especially vulnerable are companies that offer engineering services. Underlying factors for the difficulties to provide competitive services on the market for engineering servi
Abstract: Employer branding process that creates the best match possible between the employer and the employee, leads to a business satisfaction and a person-organization fit. Not surprisingly, an efficient employer branding strategy also decreases the labour turnover rate within the company and helps to retain the talent. Naturally, the specified situation is desired by the employer and by the po
I believe that vision, image and identity, brand and positioning are all parts of repositioning process. When repositioning, company has to decide if it is going to compete with same attributes as before or if company is entering totally new competitive domain with new dimensions. Fleur de Santé has changed its identity and chose which parts of it to point out; history, brand and natural ingredien
The first three US Presidents of the century have, to say the least, had differing views concerning the nature of climate change and how this issue is addressed most appropriately – as noted by the fact that the issue has gone back and forth between being a security issue and basically disappearing from the security agenda altogether. In order to shine a light on how this has happened, this study
The number of supply chain disruptions has increased over the last couple of years. The Covid-19 Pandemic, blockage of the Suez Canal and Russian invasion of Ukraine are some well-known examples of disruptions. Academia seems to have noticed the increasing disruptions and has explored proactive Supply Chain Risk Management (SCRM) as an approach to address this. Consulting firms also suggest compan
Titel: Musikens Budskap - Mytologi och folktro som tema i instrumental konstmusik Författare: Erik Valdemar Sköld Handledare: Francisca Skoogh I denna skriftliga uppsats redogör jag för bakgrunden och arbetsprocessen till tre av mina egna kompositioner vars inspirationskälla och tema är kopplat till naturen och nordisk mytologi. Frågeställningen lyder följande: vilka tillvägagångssätt inom programIn this essay, I describe the background to and work process behind three of my own compositions which are inspired by nature and Nordic mythology. I asked myself: which approaches, from programmatic music throughout history, can I use in my own work as a composer? I go through some historical examples that use references to nature, and summarise literature about program music and affects, in orde
Ersättningen till ledande befattningshavare identifierades i slutet av förra millenniet som en bidragande faktor till det låga förtroendet för näringslivet i USA och i Sverige. Lagstiftarna har sedan dess försökt komma till rätta med problemen både genom lagreglering samt via bolagskoder och listningsregler på börser. Det jag fokuserat på är vem som har makten i beslutsfattandet och hur intressen Executive officers and director remuneration was identified as a contributory factor for the low confidence-ratings in trade and industry in the beginning of this millennia. The legislator in both Sweden and in the US has since dealt with the problems by enacting laws as well as regulating through corporate governance codes and stock listing manuals. I have focused on locus of power over executive
Rationale: Adults may exhibit characteristics of both asthma and chronic obstructive pulmonary disease (COPD), a situation recently described as asthma-COPD overlap (ACO). There is a paucity of information about ACO in primary care. Objectives: To estimate the prevalence and describe characteristics of individuals withACOin primary care practices among patients currently diagnosed with asthma, COP
BACKGROUND: Gout is the most common inflammatory arthritis with a rising prevalence around the globe. While educational inequalities in incidence and prevalence of gout have been reported, no previous study investigated educational inequality in mortality among people with gout. The aim of this study was to assess absolute and relative educational inequalities in all-cause and cause-specific morta
Aims. We study the origin of tail-like structures recently detected around the disk of SU Aurigae and several FU Orionis-type stars. Methods. Dynamic protostellar disks featuring ejections of gaseous clumps and quiescent protoplanetary disks experiencing a close encounter with an intruder star were modeled using the numerical hydrodynamics code FEOSAD. Both the gas and dust dynamics were taken int
The pulp and paper industry is one of the most important industrial sectors worldwide. The focus of current pulp mills is on the production of cellulose pulp fibres and electricity. By converting traditional pulp mills into lignocellulosic biorefineries they can become a keystone in a future bioeconomy. In order to achieve this, pulp mills have to close their loops and focus on the optimal utilisa
Air pollution is one of the major environmental problems in the industrial and populated cities. Predictive mapping of urban air pollution and sharing the generated maps with the public and city officials have positive impacts on society and environment. This article presents a solution based on distributed processing concepts to generate predictive map of air pollution for the next 24 hours. Apac
The combustion engine, a well-known source of aerosols, has seen remarkable improvements regarding efficiency and emissions. A drawback of the conventional compression ignition (CI) engine is its requirement for a high cetane number fuel, i.e. diesel which contains long carbon chains forming particulate matter (PM) when combusted in the conventional diesel combustion (CDC) process. A previous stud
