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Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis

High-content real-time imaging of hormone secretion in tissues or cell populations is a challenging task, which is unlikely to be resolved directly, despite immense translational value. We approach this problem indirectly, using compensatory endocytosis, a process that closely follows exocytosis in the cell, as a surrogate read-out for secretion. The tissue is immobilized in an open-air perifusion

Label-free quantitative proteomics of the MCF-7 cellular response to a ferritin-metallodrug complex

Auoxo3 is a gold(iii) compound endowed with cytotoxic activity towards a variety of malignant cells. Encapsulation of Auoxo3 within horse spleen ferritin (Ft) improves the selectivity of the gold compound towards cancer cells over normal cells. In the current work, the changes in protein expression are presented in response to MCF-7 stimulation with Auoxo3-encapsulated Ft versus the free Au(iii) c

First-time mothers' satisfaction with their birth experience : a cross-sectional study

Objective: To explore first-time mothers´satisfaction with their birth experience using Visual Analog Scale and to identify possible risk factors for a negative birth experience.Design: A cross-sectional design using retrospective data collection from electronic medical files.Setting: A birthing center in southern Sweden, which has approximately 1400 births annually.Participants: Primiparous women

HoloScale: horizontal and vertical scaling of cloud resources

Elastic and scalable compute resources are a fundamental part of cloud computing. Efficient management of cloud resources is crucial in order to provide high quality services and applications. In this work we present a novel method for scaling cloud resources and provide stability guarantees. We do this by leveraging ideas and concepts from classic control theory, namely mid-range control and combElastic and scalable compute resources are a fundamental part of cloud computing. Efficient management of cloud resources is crucial in order to provide high quality services and applications. In this work we present a novel method for scaling cloud resources and provide stability guarantees. We do this by leveraging ideas and concepts from classic control theory, namely mid-range control and comb

Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

Oxidative DNA damage is recognized by 8-oxoguanine (8-oxoG) DNA glycosylase 1 (OGG1), which excises 8-oxoG, leaving a substrate for apurinic endonuclease 1 (APE1) and initiating repair. Here, we describe a small molecule (TH10785) that interacts with the phenylalanine-319 and glycine-42 amino acids of OGG1, increases the enzyme activity 10-fold, and generates a previously undescribed b,d-lyase enz

From Colonial Loot to Cultural Restitution: An Analysis of UNESCO Conventions and France’s SHURCWA Guidelines

This thesis investigates the restitution of cultural artefacts looted during the colonial-era, through the comparison between two United Nations Educational, Scientific and Cultural Organization (UNESCO) Conventions and the newly proposed French guideline, Shared Heritage: Universality, Restitution and Circulation of Works of Art (SHURCWA). Through a qualitative case study employing Carol Bacchi’s

Echoes of the Other: Deconstructing Julius Caesar’s and George W. Bush’s enemy portrayals of ´Barbarians’ and ‘Islamic terrorists’.

This thesis investigates how prominent political leaders construct perceptions of enemies during conflict. Using Schmitt’s Concept of the Political as a starting point, the study explores Julius Caesar’s and George W. Bush’s enemy portrayal of ‘Barbarians’ and ‘Islamic terrorists’. Utilizing a Thematic Analysis, the thesis has explored and compared the narratives of the two leaders during conflict

Developing a cosmetic cover for transtibial amputees

For someone who has undergone an amputation, it is important to be able to decide what the prosthesis should look like. Since many people today choose to have some sort of cover on their prosthesis, either to fill the void or to regain the feeling of a leg, it is very important that it is something that the user feels comfortable with. To go through an amputation is often a very shocking event

Rapport vecka32 coss

Rapport vecka 32 (publicerad 2020-08-12) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 2 Aktuell status 2 10 postnummerområden med högst uppskattad förekomst den 10 augusti . . . . . . . . . . . . . . 4 10 postnummerområden med lägst uppskattad förekomst den 10 augusti . . . . . . . . . . . . . . . 6 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka32_coss.pdf - 2026-06-13

Surface Reconstruction using Multipath Propagation in Indoor MIMO Radar

Using active radar for localization in indoor environments is challenging. By signal reflection off walls and other static objects, false targets occur, referred to as multipath "ghosts". These are a significant hinder in interpreting the data. For this reason mapping out problematic surfaces that produce reflections is an important task, preferably without prior knowledge of the room ge

Simulations of the Tenuous Upper Atmospheres of Exoplanets

Over the last decade, the interest in research on extraterrestrial planets has expanded dramatically. With the number of confirmed exoplanets having increased tenfold over the last ten years, we now know that many different types of exoplanets exist. Modern telescopes, both ground- and space-based, like the Very Large Telescope (VLT) or the James Webb Space Telescope (JWST) will drive forward the

Design of a Pole Climbing Unit

Temporary surveillance with an easily deployable surveillance unit can give a tactical advantage for police in situations when big crowds suddenly gather. It can also be used by fire department during fires or in the private security sector on construction sites and other such temporary areas requiring surveillance. This report describes the process of developing the climbing system for such a sur

Credit Ratings Influence on Payment Method - A study on European mergers and acquisitions

The aim of this study is to investigate whether the choice of payment method in mergers and acquisitions is determined by the credit rating existence of the bidder and if the credit rating level has an impact of the financing source. The methods used are Probit and GLM logit regressions. The dependent variables are payment method and fraction of cash with credit rating and credit rating level as t

MIGRATING TOWARDS A BETTER FUTURE A QUALITATIVE STUDY ON MIGRATION CHOICES AND OUTCOMES IN CAMBODIA

By answering the questions (1) What are the underlying reasons for choosing to migrate irregularly rather than regularly, and what are the implications of this choice? and (2) How and under what structural conditions are Cambodian migrants and their households using remittances? this study seeks to understand labour migration and development interactions in Cambodia, by examining why migration and

The Determinants of Capital Structure -- A Comparison of Listed Large Capitalization Non-Financial Companies in the U.S.A. and Sweden

The aim of this study is to examine the determinants of capital structure via a cross-country comparison between the U.S.A. and Sweden. With the consideration of firm specific factors, the main focus is on researching country effect and macroeconomic impacts on firms’ financing policy. Including both country and macroeconomic factors in the research allows for having a new approach on the topic. T

Rättssystemets blind spot: en kvalitativ studie om föreställningar om manlighet i kriminella gäng

This study investigates ideas about masculinity in criminal gangs, and how these ideas affect disengagement from gangs. A major problem with criminal gangs is that since they are outside society’s laws and norms, it is difficult for the judiciary to counter them with law enforcement. It is not possible to change gang member’s behaviors solely with laws, which leaves the legal system with a blind s

Lobbyism som demokratiskt problem - en studie över riksdagsledamöters syn på reglering av lobbyism

The aim of this study is to examine and gain a further understanding of the Swedish parliament’s approach to lobbying. Furthermore, to shed light on the democratic problems and values that underpin whether politicians in the parliament believe that regulations regarding lobbying should be introduced or not. The method that has been used is textual analysis. An analytical tool has been developed ba

Brandteknisk riskvärdering av Lunds domkyrka

Denna rapport är en utvärdering av brandskyddet med avseende på personsäkerheten i Lunds domkyrka. Lunds domkyrka uppfördes på 1100-talet och ligger i centrala Lund. I kyrkan hålls en mängd olika evenemang, vid stora evenemangen kan uppemot 950 personer vistas i kyrkan. Ett virtuellt platsbesök hölls med domkyrkokamrerare Mats Persson och Elisabet Nord som är ansvarig för vaktmästeriet den 25 marThe following report is an evaluation of human safety in Lund Cathedral with regards to a potential fire and evacuation. With the help of a virtual visit to the cathedral, pictures and statistics from The Swedish Civil Contingencies Agency (MSB), a general risk assessment was conducted in which possible fire- and evacuation scenarios were identified. A qualitative assessment of the probability and