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Background: The natriuretic peptides play an important role in salt homeostasis and blood pressure regulation. It has been suggested that obesity promotes a relative natriuretic peptide deficiency, but this has been a variable finding in prior studies and the cause is unknown. Aim: The aim of this study was to examine the association between obesity and natriuretic peptide levels and evaluate the
Background: The prevalence of blindness and visual impairment from glaucoma is influenced by the criteria used to define these entities, which differ between countries and regions, as well as among published reports. The objective of the present study was to ascertain the extent to which different criteria of blindness and visual impairment influence estimates of the number of patients classified
Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1
PURPOSE. To estimate the rate of visual field progression in open-angle glaucoma (OAG) subjects, by using data from population-based cross-sectional studies. METHODS. Subjects with OAG were identified in nine surveys of randomly sampled populations using standard criteria for glaucomatous optic neuropathy. Subjects were of European, African, Chinese, and Hispanic ethnicity. The measure of OAG dama
Background. Although muscle wasting may lead to decreased ammonia detoxification in cirrhosis, the potential role of lean mass depletion in hepatic encephalopathy (HE) has not been explored. Anemia, hormonal abnormalities, and psychological distress may contribute to cognitive dysfunction, but data on their potential relation to HE are limited. Methods. Data on 108 cirrhotic liver transplant candi
Background Primary Sjogren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variation
Popular Abstract in Swedish Svenska knäplastikregistret och knäledsoperation med enkammarprotes av Stefan Lewold Ledsjukdom, oftast artros, är den vanligaste kroniska åkomman hos äldre. Dess orsak är oftast inte känd och någon förebyggande behandling finns inte. Icke operativ behandling kan i tidiga stadier dämpa symptomen men då sjukdomen fortskrider får patienten allt svårare att klara sig. GenThe Swedish Knee Arthroplasty study has prospectively registered and followed knee arthroplasties done in Sweden since 1976. Demography, epidemiology and general knee prosthetic biofunction is given for 30,003 primary knee arthro-plasties and their revisions through 1992. The annual number of knee arthroplasties increased fourth fold while the relative use of Unicompartmental knee arthroplasty (UK
Popular Abstract in Swedish Avhandlingen berör aktivering av koldioxid genom inskjutningsreaktioner i palladium-kol bindningar. Detta har gjorts med komplexen (PCP)PdMe och (PCP)PdCH2CHCH2. Dessa komplex har också använts i katalytisk karboxylering of ZnMe2och tributylallyltenn. Pga. transeffekten är bindningen mellan palladium och metylgruppen kraftigt försvagad vilket visar sig i det långa bindn
Introduction Chronic rejection (CHR) of organ allografts, one of the most significant problems in modern transplantation, is not fully understood. This study sought to evaluate the influence of selected parameters on late kidney transplant function. Patients and Method The studied group consisted of eighty-six patients who received allogeneic transplants between 1988 and 1999 for leukocyte Chlam
BACKGROUND: Histamine is thought to play a central role in the regulation of gastric acid secretion. In the rat oxyntic mucosa most of the histamine is synthesized and stored in enterochromaffin-like (ECL) cells, and the rest resides in mast cells. The present study examines the role of ECL-cell histamine in the control of acid secretion in the intact, conscious rat. METHODS: Rats were treated wit
Popular Abstract in Swedish En av de viktigaste frågeställningarna inom molekylär genetik är hur uttrycket av människans ca 30-40 000 gener regleras i tid och rum. En typ av reglering som är väldigt viktig är transkriptionell reglering och denna utövas av proteiner som kallas transkriptionsfaktorer. Dessa binder till specifika områden i DNA strängarna i närheten av genkodande regioner och kan däriNeuroblastoma is a childhood tumor derived from primordial neural crest cells. The tumor cells exhibit a phenotype similar to that of developing neuroblasts, which indicates that the tumor arises due to perturbed differentiation of the sympathetic nervous system. It is well established that transcription factors control the steps leading to neuronal differentiation, and a number of basic helix-loo
BACKGROUND: The aim of this study was to evaluate the feasibility and efficacy of a modified delivery system of the distal bifurcated FEVAR component where the dilator tip was shortened to prevent damage to the renovisceral bridging stents.METHODS: All consecutive patients from a tertiary referral center that underwent a FEVAR with a custom delivery system of the distal bifurcated endograft with a
OBJECTIVE: To investigate the relation between biomarkers of inflammation and subsequent development of giant cell arteritis (GCA).METHOD: Participants in the population-based Malmö Diet Cancer Study (MDCS; N = 30447), established 1991-1996, who were subsequently diagnosed with GCA, were identified in a structured process. GCA-free controls, matched for sex, year of birth, and year of screening we
OBJECTIVES: To investigate differences in antibiotic prescription for patients with hard-to-heal ulcers assessed using a digital decision support system (DDSS) compared with those assessed without using a DDSS. A further aim was to examine predictors for antibiotic prescription.DESIGN: Register-based study.SETTING: In 2018-2019, healthcare staff in primary, community and specialist care in Sweden
Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat
BACKGROUND: Emergency computed tomography angiography (CTA) is the most important imaging modality to visualize arterial occlusions in patients with acute lower limb ischaemia (ALI). Extravascular incidental findings (EVIFs) have received less attention.PURPOSE: The aims of this study were to evaluate the incidence of EVIFs of immediate clinical relevance in patients with ALI undergoing CTA and ev
Background: Active travel has a potential to increase children ' s physical activity (PA). Pedometers offer a valid option to measure PA, but do not capture cycling activity. Children ' s self-reported cycling distances can be analyzed by the Geografic Information System (GIS). Aim: To combine pedometry and GIS mapping to identify the relative amount of cycling in children ' s PA. Study group: Of
