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OBJECTIVE: Children who undergo surgery for complex congenital cardiac disease are reported to be at increased thrombotic risk. Our aim was to evaluate long-term changes in the haemostatic system after surgery, to compare markers of activated coagulation in children having surgery with those in a healthy control population, and to relate them to adverse clinical outcome.Patients and methodsWe stud
BACKGROUND: Shortening of the atrial refractory period is the key feature of atrial electrical remodeling during atrial fibrillation (AF). During sinus rhythm (SR), assessment of the atrial refractoriness is hampered by the fact that the atrial repolarization wave (Ta wave) is largely obscured by the following QRST complex. The purpose of this study was to study the Ta wave in subjects with paroxy
In Nazi Germany 1933-1945 the medical profession played an important role, not only within the health sector but also for ideological purposes. Some physicians committed criminal acts during the war, for example in concentration camps, and where later put on trial at the Nuremberg Trials in 1946-1947, some of them also sentenced to death. What is little known outside Germany is the existence of a
Exacerbation of ST elevation associated with reperfusion has been reported in patients with myocardial infarction. However, the cause of the "reperfusion peak" and relation of its magnitude to the size of myocardial damage has not been explored. The aim of our study was to assess the correlation between the ST-dynamics during reperfusion, the myocardium at risk (MaR), and the infarct size (IS).
AimClimate change is currently altering the geographical distribution of species, but how this process contributes to biogeographical variation in ecological traits is unknown. Range-shifting species are predicted to encounter and respond to new selective regimes during their expansion phase, but also carry historical adaptations to their ancestral range. We sought to identify how historical and n
Food wastage during distribution, retail sale, and consumption is a concern of great worry. It not only affects the economics of businesses but also puts natural resources under severe stress. For example, in the UK some 800,000 tons of bakery products are purchased each year and never eaten, mainly due to short life span of the product. Earlier investigations at Lantmännen Unibake, UK have identi
Populärvetenskaplig sammanfattning Geografiska Informationssystem (GIS) är ett system för att hantera geografisk data som jämfört med traditionella forskningsmetoder gör det lättare att sammanställa och analysera dessa data. GIS började utvecklas i Nordamerika på 1960-talet och har under de senaste två decennierna haft stor påverkan på hur hanteringen av rumslig data går till. Användningsområdena Geographical Information System (GIS) is a technique that has revolutionized the way we process spatial data. The possibilities for GIS are endless and it is today used in a wide range of subject areas such as social planning, environmental monitoring and marketing. However, the process of implementing GIS is a long and usually runs in to a lot of problems. The aim of this study is to compare and
Listening to employees in a crisis is simultaneously more difficult and more important. This presents a problematic and vicious cycle for organizations. Although employees play a central role during a crisis, only a limited amount of research has been done to learn more about their perspective in the field of crisis communication research. Therefore, this study aimed to better understand the role
Gestures are used in a pragmatic way in interactive contexts such as conversation. Agreement between interlocutors is an ordinary aspect of talk-in-interaction, which is expressed through various types of utterances and gestures. The interlocutors’ status, such as gender and familiarity, may affect both their verbal and non-verbal behavior as previous research has shown. This study investigates th
In the Mekong region, sustainable water resource management is a significant challenge for all countries involved. In Cambodia, where rice production is crucial for household food security and export, groundwater is increasingly used for irrigation during the dry season, leading to higher rice yields. However, this unplanned and unregulated use of groundwater is causing depleting groundwater level
The dynamics of China’s complex policy process, shaped by the decentralization reforms of the 1980s, remain the subject of much discussion. As China spent three years adhering to its eradication strategy in response to the COVID-19 pandemic, it seems that the relevant theories from the past need to be updated. The purpose of this study was to understand how irrational decisions were made and why u
Enterprise resource planning (ERP) systems are far reaching within organisations, making ERP implementations highly susceptible to failure. This thesis investigates how change professionals of a large international organisation perceive the role of gamification and artificial intelligence (AI) during ERP implementation and how it can be used to enhance training. While training is widely acknowledg
In 2016, after decades of armed conflict, the Colombian government signed a peace agreement with the Revolutionary Armed Forces of Colombia – People's Army (FARC - EP). Nevertheless, the hopes for peace have not been realised, since violence, assassinations of social leaders, displacement of local communities and environmental degradation still occur. New groups are taking over the areas forme
The work environment and especially the psychosocial work environment influence the mental and physical well-being of employees. The aim of this study was to identify and analyse the state of knowledge regarding nurses’ work situation, health, and person-centred work during the COVID-19 pandemic through a systematic review. Methods: Systematic Review, nine included articles. The theoretical swAge
Introduction Systemic inflammation is postulated to mediate heat stroke and heat-related organ injury, yet acute inflammatory responses among heat-stressed workers remains poorly understood. We aimed to describe neutrophil mobilisation and potential release of DNA during heat stress in multiple hot occupational settings and a controlled experimental setting. Methods Neutrophil:lymphocyte ratio (NL
Fibroblasts are dynamic structural cells that direct both beneficial tissue repair and pathological organ fibrosis through interactions with tissue-resident type 2 lymphocytes (T2Ls) and type 3/17 lymphocytes (T3Ls). The cytokines interleukin-13 (IL-13) and IL-17A, produced by T2Ls and T3Ls, respectively, are linked to both tissue inflammation and fibrosis, but how their spatial positioning influe
We investigated dynamic changes in nicotinamide adenine dinucleotide (NAD+) metabolism in the human occipital lobe using ultra-high field 31P functional magnetic resonance spectroscopy (fMRS) at 7 T. Twenty-five healthy volunteers (mean age 24 ± 4 years, 10 females) performed a visual task alternating between fixation and flashing checkerboard stimuli. 31P MRS spectra were acquired from a visual c
Major depressive disorder (MDD) has been linked to altered brain networks and might be relieved by music therapy. Yet, the neurophysiological basis, especially the functional network mechanism, of music therapy on depression remains poorly understood. Here, we apply a novel dynamic module detection method based on block term decomposition (BTD) to examine the reorganization of time-varying topolog
