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Objective To characterize the redistribution patterns of zinc and calcium ions during human sperm capacitation and to investigate their roles in sperm maturation and fertilization. Design In vitro experimental study using synchrotron-based x-ray fluorescence microscopy and complementary immunohistochemistry to assess elemental changes during different capacitation stages at nanometric spatial reso
The cell cycle is a key regulator of endothelial cell specification into tip and stalk cell phenotypes, which are essential for angiogenesis in both normal development and pathological conditions. While the tumor suppressor p53 is known to regulate the cell cycle and influence cell fate, its role in modulating the cell fate of these phenotypes remains unclear. Using non-genotoxic small molecule an
Moult, the regular replacement of feathers, is a resource-intense avian annual-cycle stage. Resource allocation to support feather regrowth may require downregulation of other physiological processes, such as immune function, which is critical for preventing disease-related mortality. At the same time, the emergence of new feathers may increase the risk of skin injury and infection, potentially re
This study examines teachers’ use of evidence-based language learning techniques in the classroom and possible impact on student engagement. Video recordings of nine primary school teachers conducting interactive book reading with their students were analyzed both according to the Communication Supporting Classroom Observation Tool-Language Learning Interactions (CSCOT-LLI) and descriptively. QThis study examines teachers’ use of evidence-based language learning techniques in the classroom and possible impact on student engagement. Video recordings of nine primary school teachers conducting interactive book reading with their students were analyzed both according to the Communication Supporting Classroom Observation Tool-Language Learning Interactions (CSCOT-LLI) and descriptively. Q
To further clarify the mechanisms maintaining chronic atrial fibrillation (CAF), a method identifying preferable activation patterns of the atria during fibrillation, by time averaging of multiple discrete excitation vectors, was developed. Repeated recordings, each of 56 atrial bipolar electrograms simultaneously acquired during 8 s, were made at multiple sites in the right atrial free wall and t
Objectives: To analyse and present the outcome of longitudinal change and possible subgroups with respect to Activities of daily living (ADL) function measured by different scales (PSMS, FAST and IADL) in patients treated with donepezil for three years (n=435). Methods: The Swedish Alzheimer Treatment Study (SATS) is an open, 3-year, multicentre study in a routine clinical setting. The patients we
Bringing together studies from across the Nordic region, this book examines the challenges brought by the COVID-19 pandemic, with a particular focus on vaccine hesitancy. Shedding light on the political tensions that emerged as a result of the pandemic and the debates that ensued both within and between the Nordic nations, it investigates the vociferous discussions surrounding the COVID-19 vaccine
We evaluated biotic and abiotic predictors of rest-phase hypothermia in wintering blue tits (Cyanistes caeruleus) and also assessed how food availability influences nightly thermoregulation. On any given night, captive blue tits (with unrestricted access to food) remained largely homeothermic, whereas free-ranging birds decreased their body temperature (T (b)) by about 5 degrees C. This was not an
This study examines associations between prenatal exposure to tobacco smoking and adverse behaviour in the offspring.
In our previous papers polyethylene degradation during extrusion coating has been studied and the type of degradation products that are formed and from which step they originate have been discussed. A trained sensory panel has rated the off-flavor intensities in water samples that have been in contact with various extruded films. Encouraged by the results from these investigations and the document
Nitrous oxide and isoflurane have different effects on absolute cerebral blood flow (CBF) and regional distribution of CBF in humans. In this study we examined the effects of isoflurane in combination with nitrous oxide on CBF. We studied 10 patients (two groups of five patients, ASA I) anaesthetized with 50% nitrous oxide and either 0.5 or 1.0 MAC of isoflurane during normocapnia (PaCO2 5.7 kPa)
Abstract SETTING: Sweden under transition from high to low tuberculosis (TB) incidence from 1920 to 2009. OBJECTIVE: To correlate estimates of TB infection in birth cohorts with the longitudinal incidence of active TB to assess the long-term risk and time pattern of reactivated TB. DESIGN: Time trend analysis on TB incidence using age-cohort modelling. RESULTS: The overall TB incidence decrease
