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Isolates of Listeria monocytogenes (n = 932) isolated in Sweden during 1958-2010 from human patients with invasive listeriosis were characterized by serotyping and pulsed-field gel electrophoresis (PFGE) (AscI). Of the 932 isolates, 183 different PFGE types were identified, of which 83 were each represented by only one isolate. In all, 483 serovar 1/2a isolates were distributed over 114 PFGE types
BACKGROUND: This clinical study aimed at investigating the impact of postoperative thoracic epidural analgesia on extracellular glycerol concentration and glucose metabolism in subcutaneous adipose tissue, using the microdialysis technique. The sympathetic nervous activity, which can be attenuated by epidural anesthesia, influences lipolysis and the release of glycerol. METHODS: Fourteen patients
Objective: To study whether transient hyperglycemia adversely affects cerebral energy metabolism in patients with severe traumatic brain lesions. Design and setting: Prospective, nonrandomized study in the neurosurgical intensive care unit of a university hospital. Patients: 108 patients treated for severe traumatic brain lesions. Interventions: All patients were treated according to neurosurgical
If exercise is to be recommended during growth, benefits in bone mineral density (BMD) must be maintained in old age and shown to prevent fractures. Our cross-sectional study of soccer players suggests that a high BMD is no longer recorded after retirement and fracture frequency is no less than predicted in old age.
The aim of this study was to follow, during standardized initiation of thiopurine treatment, thiopurine methyltransferase (TPMT) gene expression and enzyme activity and thiopurine metabolite concentrations, and to study the role of TPMT and ITPA 94C > A polymorphisms for the development of adverse drug reactions. Sixty patients with ulcerative colitis or Crohn's disease were included in this open
Hyperhomocysteinemia is a risk factor for atherosclerosis and venous thrombosis, probably exerting its effects through endothelial function. Homocysteine levels are lowered by folate supplementation, and such treatment improves endothelial function. However, whether folate supplementation decreases vascular risk and improves survival is unknown. The aim of this study was to evaluate endothelial fu
This paper summarizes the results of studies of the Late Weichselian periglacial environments carried out in key areas of northern Eurasia by several QUEEN teams (European Science Foundation (ESF) programme: "Quaternary Environment of the Eurasian North"). The palaeoglaciological boundary conditions are defined by geological data on timing and extent of the last glaciation obtained in the course o
Nitric oxide (NO) is an important signalling molecule that has been suggested to be a key molecule for induction and maintenance of migraine attacks based on clinical studies, animal experimental studies and the expression of nitric oxide synthase (NOS) immuno reactivity within the trigeminovascular system. Sensitisation of the trigeminal system including the trigeminal ganglia neurones is believe
Objective: to explore the views and experiences of care of lesbian women during pregnancy and childbirth. Design, setting and participants: a qualitative study of 18 lesbian women in southern Sweden. Findings: valid text units were formed through categorisation into four main categories: recognition of sexual orientation; openness; relationships within the homosexual family; and different encounte
We present a study of the surface stoichiometry and contamination of La0.7Sr0.3MnO3 thin films following exposure to air and subsequent in vacuo preparation. Samples were studied using both soft X-ray synchrotron photoemission (hv = 150 to 350 eV) and traditional Mg-K alpha XPS (hv = 1253.6 eV) whilst annealing incrementally to approximate to 510 degrees C in low pressures of O-2. In all cases, a
Several deep Greenland ice cores have been retrieved, however, capturing the Eemian period has been problematic due to stratigraphic disturbances in the ice. The new Greenland deep ice core from the NEEM site (77.45°N, 51.06°W, 2450 m.a.s.l) recovered a relatively complete Eemian record. Here we discuss the cosmogenic (10)Be isotope record from this core. The results show Eemian average (10)Be con
Competitive breath-hold divers try to achieve maximum times, depths, or distances underwater, thereby risking hypoxic syncope. In the present study, the cardiorespiratory responses to dynamic apnea (simultaneously initiated apneas and dynamic leg exercise) were investigated in 10 breath-hold divers. The divers performed 60 s dynamic apneas with the face in air (A) or face immersed in cold water (A
We tested the hypothesis that controlled hypoxemic resuscitation improves early cerebral metabolic and electrophysiological recovery in hypoxic newborn piglets. Severely hypoxic anesthetized piglets were randomly divided into three resuscitation groups: hypoxemic, 21% O2, and 100% O2 groups (8 in each group). The hypoxemic group was mechanically ventilated with 12-18% O2 adjusted to achieve a cere
Recent large-scale cDNA cloning studies have shown that a significant proportion of the transcripts expressed from vertebrate genomes do not appear to encode protein. Moreover, it was reported in mammals (human and mice) that these non-coding transcripts are expressed and regulated by mechanisms similar to those involved in the control of protein-coding genes. We have produced a collection of cDNA
Two mixed-phase precipitation events were observed on 21 September and 20 October 2010 over the southern part of Finland during the Light Precipitation Validation Experiment (LPVEx). These events have been simulated using the Weather Research and Forecasting Model coupled with spectral bin microphysics (WRF-SBM). The detailed ice-melting scheme with prognosis of the liquid water fraction during me
