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Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei
The Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
To investigate a possible time trend in serum concentrations of persistent organochlorine pollutants (POPs), representative samples of the young (median age 18 years) Swedish male population were investigated in the years 2000 and 2004. Due to their low age, these men were assumed not to have reached steady state of body burdens of POPs, why their serum concentrations were considered to represent
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We
Kursguide - Course Syllabus • • • • • Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 2019-03-20 to be valid from 2019-08-01, spring semester 2020. General Information The course is included in the second semester of the Master of Science (120 credits) programme in Service Management and is the second course specific to the
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/kp_smmv26_eng_190320_vt20.pdf - 2026-07-16
Eutrofiering det oönskade fenomenet av hög näringstillförsel i ett akvatiskt system, är för det mesta ett resultat av mänsklig påverkan: industriellt och urbant avloppsvatten, avrinning av gödningsmedel från odlad mark, och förbränning av fossila bränslen. Studien av de främsta faktorerna som bidrar till eutrofiering (t. ex. variationer i kvävets kretslopp), är viktigt för förståelsen av dess negaEutrophication, the undesired phenomenon of high nutrient loads in an aquatic system, is mostly caused by human impact: industrial and urban waste water discharge, run-off of fertilizers from agricultural use, and combustion of fuels. The study of eutrophications' main participants such as the nitrogen cycle, are necessary to prevent it. Environmental parameters have an impact onto the effecti
Nedan finner du kontaktuppgifter för fakultets- och institutionskanslierna under semesterperioden. Använd länken som finns sist under varje avsnitt för att hitta telefon och e-post, om det inte finns angivet direkt.Vi på fakultets- och institutionskanslierna önskar dig en trevlig sommar!Fakultetskansliet (Kansli M) Kanslichef och registrator Kanslichef25 juni -12 juli: Emma Idman, stf kanslichef 1
https://www.intramed.lu.se/peoplelist/kontakt-under-sommaren - 2026-07-15
Workstream I Harmonization of methods and tools Sustainable Development Goal 2: What is Africa doing about it? Presented during the 2016 Development Research Day at Lund University, Sweden, November 10, 2016 Joseph Karugia Coordinator, ReSAKSS-ECA SDG 2 and Targets Key African Union Frameworks Status of Indicators Relevant for SDG 2 in Africa Concluding Remarks Outline Key Reference: 2015 Annual T
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/joseph_karugia_africa_and_sdg_2.pptx - 2026-07-16
Vecka Schema MVEC14 Miljövetenskap; reviderat 11 dec 2017 Industriell miljöekonomi för miljövetare VT 18 Fetstil markerar obligatoriska moment som måste genomföras för att få ut kursbetyget. Det mesta av undervisningen sker i Internationella miljöinstitutets lokaler på Tegnérsplatsen. Notera: Enskilda moment kan komma att behöva justeras tidsmässigt! Vecka Mån Tis Ons Tors Fre 3 15-19/1 13.15-16.3
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec14_schema_vt18_iiiee.pdf - 2026-07-16
Background: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) helpBackground: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) help
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively
Battery cell assembly and testing in conventional battery research is acknowledged to be heavily time-consuming and often suffers from large cell-to-cell variations. Manual battery cell assembly and electrolyte formulations are prone to introducing errors which confound optimization strategies and upscaling. Herein we present ODACell, an automated electrolyte formulation and battery assembly setup
Vecka Schema MVEC14 Miljövetenskap; reviderat 20 dec 2017 Industriell miljöekonomi för miljövetare VT 18 Fetstil markerar obligatoriska moment som måste genomföras för att få ut kursbetyget. Det mesta av undervisningen sker i Internationella miljöinstitutets lokaler på Tegnérsplatsen. Notera: Enskilda moment kan komma att behöva justeras tidsmässigt! Vecka Mån Tis Ons Tors Fre 3 15-19/1 13.15-16.3
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec14_schema_vt18_iiiee_version_2.pdf - 2026-07-16
