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Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

A comparison between mechanical properties of self-compacting concrete and the corresponding properties of normal concrete

An experimental and numerical study on mechanical properties, such as strength, elastic modulus, creep and shrinkage, of Self-Compacting Concrete, SCC, and the corresponding properties of Normal Compacting concrete, NC, is outlined in this article. The study included eight mix proportions of sealed or air-cured specimens with water-binder ratio, w/b, varying between 0.24 and 0.80. Half of the mixe

Development of a core capability framework for qualified health professionals to optimise care for people with osteoarthritis : an OARSI initiative

Objective: Develop a generic trans-disciplinary, skills-based capability framework for health professionals providing care for people with OA. Design: e-Delphi survey. An international inter-professional Delphi Panel (researchers; clinicians; consumer representatives) considered a draft framework (adapted from elsewhere) of 131 specific capabilities mapped to 14 broader capability areas across fou

No title

Course evaluation Course: Probability theory MASC01 Evaluated on LTH: Yes Lecturer: Tatyana Turova Number of students: 39 Response frequency: 13% Grades 14 VG, 13 G, 12 U Summary: Students who answered were overall satisfied. There was a very low response frequency so the reults are uncertain. Comments: The course will essentially be held in the same way next time. 1 Report Course Evaluation, FMSF

https://www.maths.lu.se/fileadmin/maths/utbildning_education/KU_Probability_theoryMASC01.pdf - 2025-11-03

Engineering of pyranose 2-oxidase: Improvement for biofuel cell and food applications through semi-rational protein design

Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac

Field2

How do we describe a location on earth? How do we describe a location on Earth? Geodetic reference system http://www.google.co.uk/imgres?imgurl=http://4.bp.blogspot.com/-v2sej--Hf9Y/TbGzN0FeN7I/AAAAAAAAAQ0/dXTA6XAP7Nk/s1600/earth-3d.gif&imgrefurl=http://ods-destruction-carbon-credits.blogspot.com/2011/04/happy-earth-day-from-remtec.html&usg=__1-2G0CU8X0-43x3j7NY4oN1vYS8=&h=1024&w=1024&sz=266&hl=en

https://www.nateko.lu.se/sites/nateko.lu.se/files/field2.pdf - 2025-11-06

Studies on Neuropsychiatric Manifestations and Genetic Factors in Systemic Lupus Erythematosus

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou

Impact of future climate scenarios on peatland and constructed wetland water quality : A mesocosm experiment within climate chambers

Water purification is one of the most essential services provided by wetlands. A lot of concerns regarding wetlands subjected to climate change relate to their susceptibility to hydrological change and the increase in temperature as a result of global warming. A warmer condition may accelerate the rate of decomposition and release of nutrients, which can be exported downstream and cause serious ec

Mapping the biotic degradation hazard of wood in Europe - Biophysical background, engineering applications, and climate change-induced prospects

Construction using timber has seen a resurgence in light of global climate mitigation policies. Wood is a renewable resource, and engineered wood products are proving to be competitive against concrete and steel while having several advantages. However, while the renewable nature of wood in construction is a beneficial property for climate mitigation policies, the process of biodegradation introdu

När den artificiella intelligensen tar över - Särskilt om ansvar vid en due diligence

Idag befinner vi oss i den så kallade fjärde industriella revolutionen, ett begrepp myntat av Klaus Schwab som är grundare och styrelseordförande av World Economic Forum. Uppgifter och funktioner som tidigare förlitat sig på den mänskliga arbetskraften kan idag automatiseras och förenklas med hjälp av artificiell intelligens. Inom advokatverksamheten har artificiell intelligens använts som komplem

Clinical studies of extended-half-life recombinant FVIII products for prophylaxis in adults and children : A critical review from the physician's perspective

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

The Triangle of Mistrust: A Utility's Struggle to Engage Effectively in the Informal Settlements of Nairobi

“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san

Serum proteome profiles in patients treated with targeted temperature management after out-of-hospital cardiac arrest

BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p

Protein Engineering Allows for Mild Affinity-based Elution of Therapeutic Antibodies

Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl

Amnetva 170107

Microsoft Word - Amnetva 170107.docx Ämne 2 musik, Estetiska fördjupningskurser Innehåll Totalt omfattar de estetiska fördjupningskurserna 90hp och läses vid Musikhögskolan i Malmö. Varje kurs omfattar 30 eller 60hp. Sammanlagt kan tre kurser väljas, alternativt två om en av kurserna är Musikproduktion 60hp, Arrangering/ komposition 60hp, Körledning/ kördirigering 60hp eller Rytmik 60hp. Om man ön

https://www.mhm.lu.se/sites/mhm.lu.se/files/amnetva_170107.pdf - 2025-11-06