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Background: Epidemiological studies on the association between maternal exposure to persistent organic pollutants (POPs) and fetal growth alteration report inconsistent findings which weights in favor of additional studies. Methods: Blood samples were collected from interviewed pregnant women in Greenland (572), Kharkiv (611) and Warsaw (258) and were analyzed for CB-153 and p,p'-DDE by gas chroma

Denna studie behandlar fuktförhållandena i regnexponerade träkonstruktioner, d.v.s. träkonstruktioner som når höga fuktkvoter. Särskilt fokus var på mikroklimatet (klimatet på träets yta) och materialklimatet (träets fuktkvot) i anslutningar. Metoder för att mäta mikroklimatet, d.v.s. våttider på en träyta och varaktighet av vatten i spalter, utvecklades liksom en metod för att mäta fuktkvot nära This thesis concerns the moisture conditions in rain exposed wood structures, i.e. wood exposed to high moisture levels. The focus was on the microclimate (the climate at the wood surface) and the material climate (the wood moisture content) in joints. Methods for determination of microclimate, i.e. the duration of moisture on a wooden surface and the duration of water trapped in gaps between two

It is generally recognised that agricultural intensification has lead to simplification of landscape structure, but it has not been clarified if this is a ubiquitous relationship. That is, it has been an open question whether agricultural intensity and landscape simplicity should be regarded as one single or as two separate dimensions. To evaluate this we analysed landscape data in 136 different 1

BACKGROUND: Associations between cadmium (Cd) and kidney function have been reported even at low levels of exposure in the general population. Recently, the causality of these associations has been questioned. OBJECTIVES: We examined associations between urinary Cd (U-Cd; a biomarker of exposure) and urinary proteins that are used as biomarkers of kidney effects, based on repeated short-term sampl

BACKGROUND: Cadmium (Cd) is a human toxicant and carcinogen. Genetic variation might affect long-term accumulation. Cadmium is absorbed by iron transporters. OBJECTIVES: To evaluate the impact of iron homeostasis genes (divalent metal transporter 1 SLC11A2; transferrin TF; transferrin receptors TFR2 and TFRC; ferroportin SLC40A1) on Cd accumulation. METHODS: Subjects were non-smoking women living

One of the largest sources of uncertainties in modelling of the future global climate is the response of the terrestrial carbon cycle. Studies have shown that it is likely that the extant land sink of carbon will weaken in a warming climate. Should this happen, a larger portion of the annual carbon dioxide emissions will remain in the atmosphere, and further increase global warming, which in turn

Quantitative Magnetic Resonance Imaging (MRI) is a research tool, used more and more in clinical practice, as it provides objective information with respect to the tissues being imaged. Pixel-wise T1 quantification (T1 mapping) of the myocardium is one such application with diagnostic significance. A number of mapping sequences have been developed for myocardial T1 mapping with a wide range in ter

We have studied, by a combined in vitro and in vivo approach, the relation between the inhibitory action of N(G)-nitro-l-arginine methyl ester (L-NAME), a selective inhibitor of nitric oxide synthase (NOS), on the activity of islet constitutive NOS (cNOS) and glucose regulation of islet hormone release in mice. The cNOS activity in islets incubated in vitro at 20 mM glucose was not appreciably aff

Structural and mechanical alterations during hypertrophy of the rat portal vein were investigated. Growth of the vessel was induced by a partial ligature of the vessel causing an increased transmural pressure. Vessel segments from animals kept with ligature for 1, 3, 5 and 7 days, were compared with vessels from sham-operated animals. Maximal active force and vessel cross-sectional area increased

The effects of various glycosaminoglycans (GAGs) on the growth rate of normal fibroblasts and a fibrosarcoma cell line (HT 1080) were examined. Cells were grown in 96-well microplates in the absence or presence of serum mitogens, epidermal (EGF), platelet-derived (PDGF), acidic fibroblast (aFGF), or basic fibroblast growth factor (bFGF). Cell number was measured by using crystal violet to stain ce

The ‘BOADICEA’ Web Application (BWA) used to assess breast cancer risk, is currently being further developed, to integrate additional genetic and non-genetic factors. We surveyed clinicians’ perceived acceptability of the existing BWA v3. An online survey was conducted through the BOADICEA website, and the British, Dutch, French and Swedish genetics societies. Cross-sectional data from 443 partici

Background Results on the association between prenatal exposure to methylmercury (MeHg) and child neuropsychological development are heterogeneous. Underlying genetic differences across study populations could contribute to this varied response to MeHg. Studies in Drosophila have identified the cytochrome p450 3A (CYP3A) family as candidate MeHg susceptibility genes. Objectives We evaluated whethe

BACKGROUND: Cancer occurrence among older people with intellectual disability (ID) is poorly documented, so we investigated the frequency and distribution of cancer in older people with ID compared with the general population.METHOD: People with ID who were ≥55years old and alive at the end of 2012 (n = 7936; ID cohort) were identified through a national register of people with ID who received soc

This study deals with the desalination plant at the Eastern Mediterranean University (Cyprus) and its environmental impact. The reverse osmosis plant produces normally 42m3/hr potable water from 120m3/hr feed. The feed concentration reaches up to 36,000ppm TDS, while an approximate amount of 73.8m3/hr is led out from a pipe of 10inches diameter with a concentration of about 56,000ppm and the perme

Den termiska klimatupplevelsen påverkas mest av lufttemperaturen som är enkel att mäta med en vanlig termometer, men för att ta reda på hur temperaturen i ett rum upplevs räcker det inte med att enbart undersöka lufttemperaturen. Även om lufttemperaturen ligger på en komfortabel nivå så kan en kall yta i närheten få personen att känna att det är kyligt i rummet och på motsvarande sätt kan varma ytThe thermal climate experience is most affected by air temperature that is easy to measure with a standard thermometer, but to find out how the temperature in a room is felt it is not enough to merely examine the air temperature. Even if the air temperature is at a comforta-ble level, then a cold surface near get the person to feel that it is chilly in the room and cor-respondingly the hot surface

Människor spenderar mycket tid inomhus, närmre 90 % av sin livstid. För att erhålla ett bra inneklimat med god luftkvalité krävs att byggnader ventileras. Därför utrustas de ofta med mekaniska ventilationssystem. Trots detta är SBS (Sick Building Syndrome) ett allvarligt problem. Orsaken till att vissa byggnader blir ”sjuka” tros bero på bland annat dålig ventilation. För att avgöra om ett ventilaPeople spend a lot of time indoors, closer to 90% of their lifetime. To obtain a good indoor climate with good air quality buildings need to be ventilated. Therefore, they are often equipped with mechanical ventilation systems. Nevertheless, SBS (Sick Building Syndrome) is a serious problem. The reason that some buildings become "sick" is believed to be due to, among other things, poor v

When the public library in Malmö presented the forthcoming implementation of IMMS (Intelligent Material Management System) a debate followed in which both pros and cons were put forth. IMMS, a developed stock management system, introduces new ways for libraries to handle their physical collections. With a joint floating collection, the system introduces an algorithm, batch management and chaotic s

Background: Access to safe and reliable water and sanitation remains a critical public health and development challenge, with rural and low-income communities being disproportionately affected by inadequate services and heightened exposure to waterborne diseases. Despite global efforts and infrastructure-based progress indicators, significant disparities persist, and these often overlook users’ pe

The myth of the user - a study of the user discourse and its visionaries This study is a discourse analysis of the visions that implicitly are expressed in different texts about user-centered library theory. Several other studies have analyzed the discourse and conceptualization of how the user is expressed in the library debate. Therefore we have chosen to analyze the visions that are expressed

The purpose of this study is to focus on library service for children in a hospital, which in turn is seen in relation to a traditional children s library. Four aspects of library work were investigated. These aspects were working methods, partners of co-operation for the libraries, media policy (acquisition, use of the collection and circulation procedures), as well as programme activities for ch