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Public collaborations and wicked issues - A study of collaboration structures in dealing with violence in close relationships

To address wicked issues, public authorities depend on each other. Yet an ongoing trend within contemporary public administration has been to streamline and decentralize welfare service. Consequently, the need for public agencies to work through inter-organisational collaborations has increased. Substantial knowledge of how this works in practice is however lacking. The aim of this thesis is to u

Multinodal High Throughput Acoustic Trapping

En ny akustisk infångningsenhet med kraftigt ökad kapacitet kan anrika nanopartiklar från kroppsvätskor. Det finns otroligt mycket information att utvinna ur biologiska vätskor som blod och urin. Biomolekyler som proteiner, blodkroppar och RNA kan säga väldigt mycket om en patients hälsa. Denna information är därför väldigt användbar för läkare när de ska sätta diagnoser, men för att få ut någonThis thesis outlines the design and construction of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. In acoustic trapping, a strong, localised acoustic field is generated inside a channel. This field can capture and retain particles against a flow, allowing for nanoparticle purification and enrichment without the need for ul

Ventilation strategies for road tunnels in different countries and consequences using Fixed Fire Fighting System (FFFS)

A study is carried out on the ventilation strategies for road tunnels in different countries and consequences using fixed fire fighting systems (FFFS). The type of ventilation strategy for road tunnels can ensure the safety of people during the evacuation stages and protection of the rescue services during their intervention of the fire. Ventilation strategies vary from country to country and ther

The modeling of drug-induced changes in ion channel kinetics and firing properties in fast-spiking interneurons: a computational study

Interneurons have been found to be important for normal cognitive function. Impairments to their growth or signaling have been indicated to be involved in the development of schizophrenia, autism and epilepsy. Defective functioning in GABA:ergic interneurons has been linked to undesired desynchronous firing in neural signals as a consequence of these interneurons firing too infrequently or not at

Development of characterization methods for lignocellulosic biogas substrates

Populärvetenskaplig sammanfattning av examensarbetet Utveckling av karaktäriserings-metoder för lignocellulosarika biogassubstrat. Smältande isar, extrema naturkatastrofer och rekordhöga temperaturer; det rapporteras daglig-en om nya händelser som påstås ha orsakats av den globala uppvärmningen. De flesta svenskar är numer familjära med uttrycket och miljömedvetenhet är något som blir mer och mer As the need of environmentally friendly alternatives to fossil fuels is growing bigger, so is the need for knowledge and research around possible new raw materials that could serve that pur-pose. One discussed product is biogas. Since biogas can be produced from not only food waste and wastewater residue, but from any substrate that contains fats, proteins and/or car-bohydrates, with the help of d

Återbruk av byggprodukter i nybyggnation av bostäder - en studie av klimatpåverkan, kostnad och genomförbarhet

År 2045 har Sverige som mål att ha netto-noll utsläpp av växthusgaser. Från och med år 2019 betyder det att utsläppen måste minska med 6–10 % per år. År 2018 stod bygg- och fastighetssektorn i Sverige för 21 % av landets utsläpp av växthusgaser, vilket motsvarade 11,8 miljoner ton koldioxidekvivalenter. Om de utsläpp på 5,8 miljoner ton koldioxidekvivalenter som genererades på grund av import av sIn 2018 the Swedish construction and real estate industry accounted for 21 % of the country’s greenhouse gas emissions. In 2045, Sweden aims to reach net zero emissions of greenhouse gases. This study aimed to analyse the possibilities and the potential of reuse of construction products in new residences based on the aspects climate, cost and feasibility. Two products were selected, one due to bei

Defining the Voice of Montreal: Exploring Possibilities for Human-Machine Companionship

This thesis explores the possibility for (re)defining the relationship between humans and robots with conversational interfaces. It does so by looking at the creation process of a voice and text-based virtual assistant for tourists from the perspective of critical posthumanism and posthuman performativity. In a reflexive fashion, I analyze my involvement in a tech start-up, in order to argue that,

Small Scale Monoclonal Antibody Purification Platform

Småskalig plattform för upprening av monoklonala antikroppar Utvecklingen av en uppreningsplatform för antikroppar visar en 30% ökning i produk-tivitet med hjälp av parallella flödesbanor. Det är nu också möjligt att upprena ännu fler prov per körning än tidigare. Utvecklingen av nya antikroppar blir allt mer viktigare i dagens samhälle för att kunna förbättra vår analytiska och diagnostiska föThe aim of this project is to transfer and implement a monoclonal antibody purification process that is traditionally done on an ÄKTAxpress to another machine called the ÄKTA pure. This is due to the fact that the ÄKTAxpress is being discontinued by the manufacturer and a replace-ment machine is needed for the time being. The project will include developing some new meth-ods that might also highli

Expression of connexin 43 gap junctions and hemichannels following cerebral ischemia in near-term fetal sheep

Connexins are proteins that make up the gap junctions that directly link the intracellular spaces of neighboring cells. Each gap junction is formed by the joining up or docking of two hemichannels in the cell membranes. It has been proposed that the gap junctions themselves or opening of hemichannels to the extracellular space may allow the spread of cytotoxic signals after injury, leading to prog

How does modern media impact decision-making in high-risk organizations?

Accidents always get a lot of public attention. Journalists appear at the site of an accident, taking pictures and making interviews with professionals and eyewitnesses. With the emergence of smartphones, online-media, and social media platforms such as Twitter, Facebook, Instagram, etc. everyone became a journalist. It is no longer only accidents catching public attention but also near misses, sm

In-vivo study on the stability of the use of gas absorption spectroscopy as a technology for assessing sinus cavity size and oxygen gas concentration

Stabilitetsmätningar på bihålans storlek och O2-koncentration med hjälp av gasabsorptionsspektroskopi. Mätningar på bihålor med gasabsorptionsspektroskopi är stabila i tiden. Skillnader mellan den högra och vänstra sidan samt skillnader mellan individer har noterats. Bihåleinflammation är en vanlig sjukdom som i 85% av fallen orsakas av virus och i resterande fall av bakterier. Trots detta, försSinusitis is a common disease caused by a virus or bacteria, with 84% to 91% of cases caused by a viral pathogen. However, physicians prescribe antibiotics for this disease in 85% of all cases. GPX Medical is a company working on the development of a medical device which, by means of absorption spectroscopy, can determine whether the disease is caused by virus or bacteria supporting, thus, the doc

Byggavfall från nybyggnation av flerbostadshus

I Sverige gav byggbranschen under 2020 upphov till drygt 14 miljoner ton avfall, vilket medför en betydande klimatpåverkan. För att bland annat öka mängden avfall som går till materialåtervinning och minska det som går till energiåtervinning och deponi har EU infört den så kallade EU-taxonomin, vilken syftar till att klassificera ekonomiska aktiviteter efter hur miljömässigt hållbara dessa är. SThe purpose of this master’s thesis was to study construction waste produced during construction of new apartment buildings in projects where Skanska Sverige AB has been the construction contractor. The distribution of different waste fractions and its treatment methods were studied for 15 projects, from the given data. This has been compared to the criteria given in the EU taxonomy concerning con

An Investigation of Methods for Flow Measurements in a Gasketed Plate Heat Exchanger for Predictive Maintenance

For a company to stay relevant in the long term, it is essential to keep up with the latest technology and continuously consider new innovative solutions for improving products and services. The gasketed plate heat exchanger (GPHE) is a mechanical device, and this work attempts to investigate different possibilities for incorporating sensor devices and predictive maintenance systems to improve the

Energy in the Transportation System - A comparison of charging infrastructure scenarios

A functioning charging infrastructure is crucial for achieving full-scale national electrification within the transport sector. The system is likely to consist of different charging technologies, all with the main objective of providing efficient energy replenishment services. Careful planning for the deployment of this infrastructure is of high importance. The consumer segments are diverse, each

Energianalys av en äldre industribyggnad

Den globala uppvärmningen förändrar jordens klimat i snabb takt, det är främst utsläpp av växthusgaser som exempelvis koldioxid från förbränning av fossila bränslen som är orsaken. Sverige har tagit flera steg mot en hållbar energiproduktion där 65 % av elen är förnybar, men samtidigt är fossila bränslen en betydande del. Av Sveriges totala energianvändning går 25 % till att värma upp det befintliGlobal warming is changing the Earth's climate and is mainly caused by greenhouse gas emissions from, for example, fossil fuels. Sweden's energy production consists of 65 % renewable energy, but the remaining amount comes from fossil fuels. Of Sweden's total energy production, a quarter goes to heating existing buildings. Upcoming EU directives set higher requirements for energy effici

Serum phthalate levels and time to pregnancy in couples from greenland, poland and ukraine.

Phthalates are ubiquitous industrial chemicals that have been associated with altered reproductive function in rodents. Several human studies have reported an inverse association between male testosterone and phthalate levels. Our aim was to investigate time to pregnancy (TTP) according to serum levels of diethylhexyl phthalate (DEHP) and diisononyl phthalate (DiNP) metabolites in both partners. I

En studie av vindsbränder utifrån statistik och brandutredningar

This report provides a detailed study of attic fires that have occurred in Swedish apartment buildings in order to determine if there are specific technical or organizational factors that influence them. The study has been carried out by a combined analysis of rescue service statistics with case studies based on detailed fire investigations. In the case study a total of 27 fire investigations w

Neuroinflammation in Huntington’s disease - effects of fractalkine on microglia in a mouse model R6/2 of Huntington’s disease

Popular science summary: Huntington’s disease (HD) is a rare disease but more commonly found in ethnic populations belonging to Europe and North America than in those of Asian or African ancestry. This disease causes loss of neurons in different areas of the brain, that gives rise to different behavioural changes and psychological disturbances including involuntary movements and depression. The

"Tack för visat intresse. Tjänsten har nu tillsatts av annan sökande" - Vilka erfarenheter och egenskaper efterfrågas vid rekrytering av kultursekreterare, idrottslärare och receptarier?

In this paper I have investigated what factors that may affect the recruitment, such as whether the applicant is a recent graduate, parent of young children, have been trained abroad or approaching retirement. I also want to investigate how the choice of candidates is affected if there is surplus, balance or a shortage of labor as it is for cultural secretaries, for the physical education teachers

E-books and public libraries - About management of e-books at three Swedish public libraries

The subject of this Master’s thesis is the management of electronic books at three Swedish public libraries. Current statistics about lending e-books have been gathered and supplemented by interviews with librarians and head librarians from the libraries in the study. Statistics and interviews are then analysed together with the library’s policy documents by using an institutional theory. The thes