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OBJECTIVE: To determine the efficacy and safety of low carbohydrate diets (LCDs) and very low carbohydrate diets (VLCDs) for people with type 2 diabetes. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Searches of CENTRAL, Medline, Embase, CINAHL, CAB, and grey literature sources from inception to 25 August 2020. STUDY SELECTION: Randomized clinical trials evaluating LCDs (<130 g/day or

Background: The risk of sustaining a contra-lateral anterior cruciate ligament (C-ACL) injury after primary unilateral ACL injury is high. C-ACL injury often contributes to a further decline in function and quality of life, including failure to return to sport. There is, however, very limited knowledge about which risk factors that contribute to C-ACL injury. Objective: To systematically review in

We explore peoples' dispositions and practices with regard to social–ecological transformations based on a sustainable welfare policy strategy in Sweden. We draw on Bourdieu's concept of habitus to highlight the relations between social positions, dispositions, and position-takings. Using data from an own survey, we identify habitus types and place these in the space of social positions. We apply

It is widely known that the apolipoprotein E (APOE) ϵ4 allele imposes a higher risk for Alzheimer's disease (AD). Recent evidence suggests that exposure to air pollution is also a risk factor for AD, and results from a few studies indicate that the effect of air pollution on cognitive function and dementia is stronger in APOE ϵ4 carriers than in non-carriers. Air pollution and interaction with APO

Co-optimization of urban morphology and distributed energy systems is key to curb energy consumption and optimally exploit renewable energy in cities. Currently available optimization techniques focus on either buildings or energy systems, mostly neglecting the impact of their interactions, which limits the renewable energy integration and robustness of the energy infrastructure; particularly in e

Background: Several aggregate data meta-analyses have provided estimates of the effectiveness of influenza vaccination in community-dwelling elderly people. However, these studies ignored the effects of patient-level confounders such as sex, age, and chronic diseases that could bias effectiveness estimates. We aimed to assess the confounder-adjusted effectiveness of influenza vaccines on laborator

In 2013, the drinking water for one-third of the households in Ronneby, Sweden, was found to be contaminated by perfluorinated alkyl substances (PFAS, >10,000 ng/L) from Aqueous Film Forming Foam (AFFF). In utero PFAS exposure can influence birth weight, but little is known about the effects at very high levels. This study aimed to examine the association between in utero PFAS exposure and birth w

Within the humanitarian arena and since the introduction of the humanitarian reform process in 2005, the cluster approach was introduced to strengthen the cooperation and accountability between agencies working in the same field. Such an integrated approach is particularly needed and relevant in emergencies like cholera, especially in countries undergoing internal conflicts like Yemen. Several are

As 5G is entering maturity, the research interest has shifted towards 6G, and specially the new use cases that the future telecommunication infrastructure needs to support. These new use cases encompass much higher requirements, specifically: higher communication data-rates, larger number of users, higher accuracy in localization, possibility to wirelessly charge devices, among others.The radio ac

Urban flood damage leads to major costs for private house owners, insurance companies, and water and wastewater utilities. Analysis of flood damage claims can be used to improve the understanding of the details of flood damage characteristics and reasons for drainage system failures. However, few studies have used data of this kind to investigate urban flood characteristics. We examined 3113 damag

BACKGROUND: Alzheimer's disease is characterized by an abnormal increase of phosphorylated tau (pTau) species in the CSF. It has been suggested that emergence of different pTau forms may parallel disease progression. Therefore, targeting multiple specific pTau forms may allow for a deeper understanding of disease evolution and underlying pathophysiology. Current immunoassays measure pTau epitopes

Objective: Non-sustained supraventricular tachycardia (nsSVT) is associated with a higher risk of developing atrial fibrillation (AF), and, therefore, detection of nsSVT can improve AF screening efficiency. However, the detection is challenged by the lower signal quality of ECGs recorded using handheld devices and the presence of ectopic beats which may mimic the rhythm characteristics of nsSVT. M

Preventing and mitigating damage to the surroundings arising from process safety incidents is an important aspect of process safety. Risk-informed or risk-based decision-making are cornerstones in most countries’ regulatory regimes for land-use planning. However, the design and implementation of the regulations vary significantly - from countries that have chosen a highly standardized set of rules

This study investigated the variability of antioxidant compounds and capacity of four wild edible fruits from Mozambique: Adansonia digitata (AD), Dialium schlechteri (DS), Garcinia livingstonei (GL), and Syzygium cordatum (SC), collected over three consecutive years from seven locations. Antioxidant compounds including total polyphenol content (TPC), total flavonoid content (TFC), and vitamin C

Background: Depression and anxiety often reduce people’s ability to cope with everyday occupations. There is a lack of knowledge about such problems in people of working age with depression and anxiety. Aim: To describe which problems people with depression or anxiety disorders experience when performing everyday occupations and which occupations are affected. Materials and methods: Data based on

While organizations providing critical services to society must have the ability to anticipate and prepare for foreseeable threats, they also need to develop a capacity to adapt in the face of unforeseen challenges and crises. While adaptive capacity becomes manifested in a specific situation through the concrete adaptations carried out by an organization, the preconditions to adapt exist already

This study analyzes the thermal performance of an indirect-type solar dryer incorporated with a heat exchanger to recover heat from the exhaust. Data were recorded for 8 h from 9:00 to 17:00 from November to January to determine the drying rate for varying airflows from 2 l/s to 12 l/s under the weather conditions of Nepal and Bhutan. The air temperatures in multiple locations in the dryer were re

In celiac disease, intestinal transglutaminase (TG2) produces immunogenic peptides by deamidation of gluten proteins. These products drive the celiac immune response. We have previously identified an interaction between gliadin and a food additive, E304i, which prevents gliadin processing (both deamidation and transamidation) by TG2, in vitro. In this study, we investigated if E304i could prevent

Introduction: Ensuring access to clean and safe drinking water is crucial, especially in flood-prone regions where the water quality in dug wells can deteriorate due to various physicochemical factors. This research was aimed to measure the effectiveness of natural materials in improving water quality based on physicochemical parameters and to compare water quality before and after treatment in As

Non-traditional stable isotope systems are increasingly used to study micronutrient cycling and acquisition in terrestrial ecosystems. We previously proposed for zinc (Zn) a conceptual model linking observed isotope signatures and fractionations to biogeochemical processes occurring in the rice soil environment and we suggested that 2’deoxymugineic acid (DMA) could play an important role for rice