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Background/Aims: Survival for patients on renal replacement therapy (RRT) has been shown to correlate to the level of physical activity and exercise capacity. We examined whether composite measures of functional status at the start of RRT predict survival. Methods: In this retrospective study, the same physiotherapist, using a standardized battery of tests for functional status, tested 134 patient
As genetic factors can hardly explain the changes taking place during short time spans, environmental and lifestyle-related factors have been suggested as the causes of time-related deterioration of male reproductive function. However, considering the strong heterogeneity of male fecundity between and within populations, genetic variants might be important determinants of the individual susceptibi
Minor Field Studies (MFS) is a grant programme funded by Sida, offering students the opportunity to conduct field studies in countries where Sweden has active strategies for development cooperation. Shortcuts to page content:About the grantHow to applyAfter you have sent in your applicationIf you are awarded a grant Applications are open 5–25 April Contact information Maria NilssonDivision of Glob
Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). Knowledge of the incidence, risk factors, and the underlying mechanisms of AB induced by AEDs may help to facilitate management and reduce the risk of such side effects. The exact incidence of AB as an adverse e
Cyanobacteria in fresh water can cause serious threats to drinking water supplies. Managing cyanobacterial blooms particularly at small drinking water treatment plants is challenging. Because large amount of cyanobacteria may cause clogging in the treatment process and various cyanotoxins are hard to remove, while they may cause severe health problems. There is lack of instructions of what cyanoba
The porous aquifers in the area called Challapampa are the most important groundwater reservoirs that supply drinking water to Oruro city in the highlands of Bolivia. They consist of unconsolidated fluvial–lacustrine deposits, resting on a complex sedimentary bedrock and covered by a thin surficial clay layer. The settings of these geological units and the structures governing the flow patterns ha
In the β-d-galactopyranoside-binding protein galectin-3, synthetic inhibitors substituted at the 3-position of a thiodigalactoside core cause the formation of an aglycone binding pocket through the displacement of an arginine residue (Arg144) from its position in the apoprotein. To examine in detail the role of different molecular interactions in this pocket, we have synthesized a series of nine 3
Purpose: The purpose of the study, upon which this paper is based, was to contribute an improved understanding of the vertical extension of buildings, by presenting a development process for its implementation in which the key aspects to consider when planning such extensions are highlighted. Design/methodology/approach: The approach is based on linking the diffusion of innovation together with ca
Exposure of cells to adverse environmental conditions invokes a genetically programmed series of events resulting in the induction of specific genes. The fluoroquinolone antibiotic ciprofloxacin has recently been reported to upregulate interleukin-2 (IL-2) gene induction. In the present investigation, the effect of ciprofloxacin at supratherapeutic concentrations on immediate-early (<2 h) gene exp
The current climate change is calling for a drastic reduction of energy demand as well as of greenhouse gases. Besides this, cities also need to adapt to face the challenges related to climate change. Cities, with their complex urban texture and fabric, can be represented as a diverse ecosystem that does not have a clear and defined boundary. Multiple software tools that have been developed, in re
ABSTRACT: The microbiological composition of tobacco products was studied using culture and chemical analysis (of tobacco leaves) or chemical analysis only (tobacco and tobacco smoke). The chemical analyses utilized gas chromatography-tandem mass spectrometry for determining 3-hydroxy fatty acids, muramic acid, and ergosterol as markers of respectively lipopolysaccharide (LPS), peptidoglycan, and
Malignant melanoma is one of the most aggressive skin cancers with high potential of visceral dissemination. Since the information about melanoma genomics is mainly based on primary tumors and lymphatic or skin metastases, an autopsy-based visceral metastasis biobank was established. We used copy number variation arrays (N = 38 samples) to reveal organ specific alterations. Results were partly com
Bone is a composite material where tubular osteon structures surrounded by thin interfaces reinforce the tissue at the microscale. These interfaces provide alternative weak paths for crack growth and give rise to potent extrinsic toughening mechanisms. Numerical models can help to gain a deeper understanding of fracture resistance in bone, however, capturing the interface mechanics is key. For thi
Immanuel Kant wrote that the Conflict of the Faculties is a constant struggle for primacy that causes strife and ultimately undermines scholarly solidarity. His argument is a complex one, as it relates to the very ability of how to judge proper authority, what constitutes scientific truth, and how to create respect amongst a community of people representing divergent opinions. Whilst such consider
Increasing land use pressure is a primary force for degradation of agricultural areas. The drivers for these pressures are initiated by a series of interconnected processes. This study presents a novel methodology to analyze drivers of changing land use pressure and the effects on society and landscape. The focus was on characterizing these drivers and relate them to land use statistics obtained f
Prior literature in the field of corporate social responsibility (CSR) has largely focused on investigating its relationship with organizational-related outcomes, whereas the impact of CSR on consumer behavior is largely ignored in the recent literature. Further, most of the prior studies have investigated CSR with a philanthropic viewpoint, but its importance in achieving marketing-related outcom
Flooding is a natural but unavoidable disaster that occurs over time. Flooding threatens human life, property, and resources and affects regional and national economies. Through frequency ratio and MaxEnt modeling, flood sensitivity was determined in the Amu Darya River Basin in Badakhshan Province, Afghanistan. Slope, plan curvature, distance to river, rainfall, aspect, land use, elevation, Norma
The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred Knudson proposed the ‘two-hit’ model of tumour development. Since then, the efforts of researchers worldwide have substantially expanded our knowledge of Wilms tumour biology, including major advances in genetics — from cloning the first Wilms tumour gene to high-throughput studies that have revealed the genetic landsca
The objective of this work was to produce a gluten-containing food matrix (pasta) rich in dietary fiber (DF), polyphenols, and antioxidant activity, through partial substitution with a dry flour from decocted Hibiscus sabdariffa L. calyces. The food matrix was made by mixing semolina (75%) and decocted calyces flour (25%) (S75–HF25), and its proximate composition, polyphenols content, antioxidant
Pandemics such as Covid-19 have posed a set of questions concerning safe space usage given the risk of virus transmission in confined and open spaces. In this context, this report presents a risk analysis methodology for the use of crowd modelling tools as an aid to assess safety in confined and open spaces. Crowd models can be used to investigate people movement in the built environment, thus the
