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1 ORPHEUS Labelling procedure Evaluators’ report of the PhD program at the Faculty of Medicine Lund University, Sweden ORPHEUS visiting committee : Prof. Andre NIEOULLON, Emeritus Professor , Aix-Marseille University, France, Chair of the committee Prof. John CREEMERS, KU Leuven, member of ORPHEUS Executive Committee, Belgium Prof. Nebojsa LALIC, Dean of the Faculty of Medicine, University of Belg
REGULATORY DOCUMENT COVER PAGE Guidelines on third-cycle education at the Faculty of Social Sciences Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in the area covered by the guidelines. A “must” rule is to be complied with, whereas the nature of a “should” rule is more of a strong recommendation, which mea
This master thesis work concerns the effect of high-alumina additives on the selfdesication of concrete. The purpose of the work was to examine the possibilities to optimize the binder-content of concrete with regards to self-desiccation. Two highalumina additives have been examined. In the experiments 10% of the binder mass has been replaced with one of these additives. Commercially available ceme
Ever-increasing global water shortages necessitate more advanced and cost-effective water purification methods. Herein, a novel slow filtration system using natural raw zeolite is proposed as an alternative to traditional quartz sand as a filter medium. The system demonstrates excellent performance in reducing turbidity and removing methylene blue (MB). The natural zeolite-based filtration system
The power systems of drilling rigs have changed considerably since the early days of steam driven machinery. This paper reviews that progression, from mechanical and diesel electric configurations through to modern hybrid and renewable integrated systems, with a focus on the power conversion technologies that enable each stage. Coverage includes the electrical architecture of drilling rig power sy
Moisture plays a critical role in several degradation mechanisms affecting the structural components of nuclear power plants. It also significantly influences the long-term structural behaviour of reactor containments. This study presents a novel hygrothermal model that uses the relative humidity as the transport potential and accounts for the presence of a thermal gradient across the containment Moisture plays a critical role in several degradation mechanisms affecting the structural components of nuclear power plants. It also significantly influences the long-term structural behaviour of reactor containments. This study presents a novel hygrothermal model that uses the relative humidity as the transport potential and accounts for the presence of a thermal gradient across the containment
Effective control over the alignment of 2D nanomaterials in solution is critical for optimizing their macroscopic properties. However, the fundamental factors governing this alignment remain poorly understood. This study addresses this gap by investigating the disorder-to-order transition states of Ti3C2Tx MXene sheets. We specifically examine the interplay among sheet sizes, concentrations, and s
Objective. We recently showed that plasma concentration of N-terminal atrial natriuretic peptide (Nt-proANP) is strongly directly related to salt sensitivity. The aims of the present study were to test (i) whether plasma concentration of N-terminal brain natriuretic peptide (Nt-proBNP) is related to salt sensitivity and (ii) whether Nt-proANP, as a marker of salt sensitivity, differs between type
Cell surface proteins of the human gastric pathogen Helicobacter pylori, reference strain CCUG 17874, were extracted with acid glycine and fractionated by heparin affinity chromatography. The extracts were subsequently analysed using high-resolution two-dimensional gel electrophoresis (2-DE) and immunoblotting. Four proteins of low molecular masses (25-30 kDa) stained by Coomassie R-350, were iden
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction column and then elution by ethyl
Objective: The aim of the present study was to investigate the perceived anxiety, depression, sleeping habits, and participation in social activities in relation to psychotropic drug use among elderly in assisted-living facilities and to identify factors of importance for the use of these drugs. Method: The study had a cross-sectional design and included 93 residents living in old-age homes or in
In this document, a large number of mathematical models describing various physical, biological and chemical processes in a wastewater treatment plant are presented. In most cases, the models are fairly simple as they are inteded for steady-state simulations based on yearly averages of the influent wastewater charteristics. The combination of models forms a software tool namned URWARE (URban WAter
The ability to identify methicillin-resistant staphylococci by the disc diffusion method was evaluated using discs containing oxacillin (1, 5 and 10 micrograms), methicillin (10 micrograms) and cephalexin (30 micrograms). Strains of Staphylococcus aureus (67 strains) and coagulase-negative staphylococci (72 novobiocin-sensitive and 27 novobiocin-resistant strains) were studied using two inoculum d
Popular Abstract in Swedish Denna avhandling består av en tillämpad och en teoretisk del. I den tillämpade delen studeras tänkbara riskfaktorer för blodsjukdomarna myeloisk leukemi (ML) och myelodysplastiska syndrom (MDS). Den teoretiska delen tar upp några metodproblem som kan uppstå i epidemiologiska undersökningar som utnyttjar databaser innehållande uppgifter om andelen personer i olika yrkesgCase-control studies comprising telephone interviews for 333 cases of acute myeloid leukemia (AML), 226 cases of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), 330 cases of myelodysplastic syndromes (MDS), and matched controls were conducted. Information had to be obtained from next-of-kin much more often for cases (85%) than for controls (18%). Tobacco smoking was associated
Popular Abstract in English European dry extensive grasslands are biodiversity hotspots which are severely threatened by land use intensification and abandonment. In order to plan efficient conservation actions it is necessary to collect information on the current status of grasslands, their species diversity and prevailing environmental conditions. Remote sensing technology in combination with grAs a consequence of agricultural intensification, large areas of species-rich grasslands have been lost and farmland biodiversity has declined. Previous studies have shown that the continuity of grazing management can have a significant influence on the environmental conditions and the levels of plant species diversity in grassland habitats. The preservation of species-rich grasslands has become a
Popular Abstract in Swedish När man hör ordet ”klimatförändringar” tänker många direkt på en förhöjd temperatur – så kallad global uppvärmning. Även om en förhöjd temperatur är en viktig del av framtida klimatförändringar så är det inte den enda förändringen vi kan förvänta oss. Sjöar på norra halvklotet och således även i Sverige har under de senaste årtiondena fått en ökad vattenfärg. Orsaken baThe effects of increasing temperatures, in light of climate change, have been a well-studied topic during the past decades. However, aquatic ecosystems are also faced with additional challenges such as increasing water colour, known as “brownification”. Although we know that temperature and water colour will increase simultaneously this has been given little attention in ecological research. In th
The production cost of cellulolytic enzymes is a major contributor to the high cost of ethanol production from lignocellulosics using enzymatic hydrolysis. The aim of the present study was to investigate the cellulolytic enzyme production of Trichoderma reesei Rut C 30, which is known as a good cellulase secreting micro-organism, using willow as the carbon source. The willow, which is a fast-growi
PURPOSE: Previous reports have demonstrated the inhibitory effect of exogenous gamma-aminobutyric acid (GABA) on micturition. In the current study we tested whether tiagabine (Sanofi Synthelab., Newcastle-upon Tyne, United Kingdom), a GABA re-uptake inhibitor increasing endogenous GABA concentrations, would affect micturition in awake rats or influence rat detrusor contraction in vitro. MATERIALS
Popular Abstract in Swedish En mängd epidemiologiska studier har visat att fuktskador i bostaden eller på arbetsplatsen ökar risken för olika typer av hälsobesvär, t.ex. astmatiska och allergiska besvär. Exakt vad som emitteras och orsakar dessa symptom i fuktskadade byggnader är inte känt, men både kemiska och mikrobiologiska agens är misstänkta. Vidare finns behov av bättre metoder för att identIt has been shown in a large number of scientific studies that living or working in a building with mould and moisture damage increases the risk for asthmatic and allergic symptoms. However, there is a need to establish more valid methods to obtain a more nuanced picture of the wide range of different types of moisture related problems. Furthermore, the causal relationships and the biological mech
OBJECTIVE: To investigate whether a history of recurrent urinary tract infection (UTI) and/or the presence of day-wetting/urge symptoms might influence the contractile responses to the cholinergic agonist carbachol or to the sensory neuropeptide neurokinin A (NKA) in the urinary bladder in children. PATIENTS AND METHODS: Small detrusor strips were taken from the margin of the cystotomy incision of
