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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

https://www.commons-center.lu.se/previous-conferences-and-workshops - 2026-05-05

Spring Semester 2020 Semester 2 SMMV21 Methods in Social Sciences (15 credits) Syllabus Reading list For specialisation Culture and Creativity Management SMMV22 Service Development and Entrepreneurship (15 credits) Syllabus Reading list For specialisation Retail SMMV23 Service Logistics (7.5 credits) Syllabus Reading list SMMV24 Retail Marketing: Theoretical Perspectives and Concepts (7.5 credits)

https://www.ses.lu.se/en/education/study-information/syllabi-and-reading-lists/syllabi-and-reading-lists-13 - 2026-05-05

Spring 2026 Semester 2SMMY21 Methods in Social Sciences (15 credits)SyllabusReading listExaminerFor specialisation Culture and Creativity ManagementSMMX22 Service Development and Entrepreneurship (15 credits)SyllabusReading listExaminerFor specialisation Retailing and ConsumptionSMMM23 Digitalizing Stores (7.5 credits)SyllabusReading listExaminerSMMM24 Retail Development and Places (7.5 credits)Sy

https://www.ses.lu.se/en/education/study-information/syllabi-and-reading-lists/syllabi-and-reading-lists-24 - 2026-05-05

https://www.khm.lu.se/sites/khm.lu.se/files/2023-06/Exhibitions%20HT%202023-%20VT%202024.pdf - 2026-05-07

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

Bestämmelsen om tjänstefel återfinns i 20 kap. 1 § Brottsbalken vilket innebär att den som vid myndighetsutövning, uppsåtligen eller av oaktsamhet, åsidosätter vad som gäller för uppgiften genom handling eller underlåtenhet kan ställas till svars. Idag omfattas inte de kommunalt förtroendevalda i den högre beslutande förvaltningen av detta ansvar då de besitter ett partiellt ämbetsansvar. Detta pa

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

Object Shift and Event-Related Brain Potentials Mikael Rolla, Merle Hornea, Magnus Lindgrenb Department of Linguistics and Phoneticsa, Department of Psychologyb, Lund University mikael.roll@ling.lu.se 1. Introduction SWEDISH pronominal objects can either precede or follow a sentence adverb, as shown in example (1). In (1a), the pronominal object den ’it’ precedes the sentence adverb inte ’not’, wh

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_gpdb/Roll_Horne_Lindgren_CNS2007.pdf - 2026-05-04

Radio frequency identification (RFID) is a compelling technology for Internet of Things (IoT). Ultra-wideband (UWB) technology is one promising wireless technique for future RFID, especially for high-throughput sensing applications. On-off keying UWB RFID system provides high pulse rate but suffers severe collisions that limit the system throughput. This paper proposes to utilize low pulse rate co

A key task in the ESMERALDA project dealt with identifying appropriate case studies to test the ‘flexible methodology’ in its different stages of development. Case studies consist of working examples in which mapping and assessment of ecosystem services were applied to address specific decision-making problems. Testing is understood as an iterative process of co-learning that involves project part

https://www.science-library.lu.se/calendar/thesis-writing-qa-6 - 2026-05-05

https://www.science-library.lu.se/calendar/thesis-writing-qa-7 - 2026-05-05