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Protonation of Homocitrate and the E1 State of Fe-Nitrogenase Studied by QM/MM Calculations

Nitrogenase is the only enzyme that can cleave the strong triple bond in N2, making nitrogen available for biological life. There are three isozymes of nitrogenase, differing in the composition of the active site, viz., Mo, V, and Fe-nitrogenase. Recently, the first crystal structure of Fe-nitrogenase was presented. We have performed the first combined quantum mechanical and molecular mechanical (

SARs for the antiparasitic plant metabolite pulchrol. : 3. Combinations of new substituents in A/B-rings and A/C-rings

The natural products pulchrol and pulchral, isolated from the roots of the Mexican plant Bourreria pulchra, have previously been shown to possess an antiparasitic activity toward Trypanosoma cruzi, Leishmania braziliensis and L. amazonensis, protozoa responsible for the Chagas disease and leishmaniasis. These infections have been classified as neglected diseases, and still require the development

C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend.

C4b-binding protein (C4BP) is best known as a potent soluble inhibitor of the classical and lectin pathways of the complement system. This large 500kDa multimeric plasma glycoprotein is expressed mainly in the liver but also in lung and pancreas. It consists of several identical 75kDa α-chains and often also one 40kDa β-chain, both of which are mainly composed of complement control protein (CCP) d

Accumulation of Intraneuronal beta-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

Pathologic aggregation of beta-amyloid (A beta) peptide and the axonal microtubule-associated protein tau protein are hallmarks of Alzheimer's disease (AD). Evidence supports that A beta peptide accumulation precedes microtubule-related pathology, although the link between A beta and tau remains unclear. We previously provided evidence for early co-localization of A beta 42 peptides and hyperphosp

Comprehensive bioinformatic analysis of the specificity of human immunodeficiency virus type 1 protease

Rapidly developing viral resistance to licensed human immunodeficiency virus type 1 (HIV-1) protease inhibitors is an increasing problem in the treatment of HIV-infected individuals and AIDS patients. A rational design of more effective protease inhibitors and discovery of potential biological substrates for the HIV-1 protease require accurate models for protease cleavage specificity. In this stud

Att sparera gående och cyklister

Pedestrians and cyclists are so-called unprotected road users which are sensitive in the context of road safety. When it comes to road safety focus are often placed on pedestrians-cars and cyclist-cars, in this report focus are placed on the road safety between pedestrians and cyclists. Pedestrians and cyclists are often referred to a combined space, with or without a separation. The purpose of th

Plan- och volymteknikproducerade bostadshus i trä: Jämförelse av stomstabilisering för två och fyra våningar

Traditionellt produceras trähus högst i två våningar p.g.a. historiskt svårkontrollerade brän-der. Idag är byggtekniken utvecklad och det är tillåtet att bygga trähus i flera våningar. Andel trähus som byggs med prefabricerade delar ökar idag i Sverige. Genom att producera montagefärdiga element i varierande storlek förflyttas husproduktionen från byggarbetsplats till fabrik. Syftet med studien äTraditionally, wooden houses are produced with a maximum of two floors, due to historical difficulties to control fires. Today, construction technology is developed so far that it is con-sidered safe to build wooden houses with additional floors. The percentage of wooden houses built with prefabricated parts is increasing in Sweden today. By producing module elements in various sizes, house produc

Waste management in Sweden – Case study at the IKEA warehouses in Älmhult

Caroline Eliasson Avfall – en av framtidens viktigaste resurser Avfallshanteringen har i både Sverige och EU genomgått stora förändringar de senaste åren. Ny lagstiftning och nya styrmedel har implementerats och gett gott resultat genom att minska mängden avfall som deponeras. Nästa utmaning är att kunna utnyttja materialet i avfallet mer än en gång. För det krävs nya strategier. AvfallshanterThe thesis consists of a description of the waste management in Sweden today, related to a case study at IKEA’s warehouses in Älmhult. Waste is globally one of the most important environmental challenges. Waste management in Sweden has developed a lot during the past years and is now standing in front of the next big challenge: to reach higher up in the waste hierarchy. By studying the academic li

Aktuelltom vetenskap och halsa november 2008

Hjärnan i tanke & rörelse November 2008 Denna tidskrift ges ut av Medicinska fakulteten vid Lunds universitet och Universitetssjukhuset i Lund & Universitetssjukhuset MAS vid Region Skåne Aktuellt om Vetenskap & hälsa 2 a k t u el lt o m v e t ensk a p o ch hä l sa • n ov 20 0 8 Frontallobsdemens är en grupp sjukdomar som upp- täcktes i Lund på 1980-talet och som orsakas av sjukliga förändringar i

https://www.huntington-research.lu.se/sites/huntington-research.lu.se/files/aktuelltom_vetenskap_och_halsa_november_2008.pdf - 2026-05-30

Övertagande av bostad - Särskilt om huvudsaklighetskravet

I detta arbete har jag valt att göra en utredning av huvudsaklighetskravet i Äktenskapsbalk (1987:230) 7 kap. 4 §. Huvudsaklighetskravet är ett begrepp som tillämpas då makarnas egendom vid en skilsmässa skall fördelas på lotter. Detta begrepp omfattar såväl den gemensamma bostaden som bohaget, men i detta arbete tar jag bara upp vad som gäller den gemensamma bostaden. Under efterkrigstiden var de

Collaboration - Partnership

LBIC maintains extensive collaborations at regional, national and international levels, which are essential for strengthening research infrastructure, advancing technological capabilities and maximizing scientific impact. These partnerships enable knowledge exchange, shared resources and coordinated development of advanced imaging methods across disciplines.Regional PartnershipsRegion SkåneAt the

https://www.lbic.lu.se/collaboration-partnership - 2026-05-29

Your year at the Pufendorf IAS

- when does what happen? The purpose of your time here at the Pufendorf IAS is to give you the space to explore the research problems which you described in your Theme or ASG application. As you know, we don’t expect deliverables, specific research output, but we do ask that you keep certain things in mind at specific times during your Pufendorf-year. AugustTheme: What day of the week would suit y

https://www.pi.lu.se/en/whats-going-pufendorf-ias/practical-information-themes-and-asgs/your-year-pufendorf-ias - 2026-05-29

Quality assurance processes in third cycle (doctoral level) education

On this page you can read about the Faculty’s quality assurance work and about European, national and internal regulations, policies and recommendations that regulate higher education institutions and that are the starting point for the Faculty’s quality assurance processes in third cycle (doctoral level) education.The Faculty of Medicine is working systematically to maintain and develop quality i

https://www.intramed.lu.se/en/organisation-and-governance/quality-assurance/quality-assurance-processes-third-cycle-doctoral-level-education - 2026-05-29

Corvellec nsr 31 maj 2013

Handledningsaritmetik Olika marknader Olika slags värde Hervé Corvellec Institution för Service Management Campus Helsingborg Lunds Universitet NSR, 31 maj 2013 En specifik affärsmodell Public Service activities Marketing activities Waste management fees Processing activities Waste Products and recycled materials Waste management Income Incomes from sales Organization’s boundaries Landfill Olika m

https://www.ses.lu.se/sites/ses.lu.se/files/corvellec_nsr_31_maj_2013.ppt - 2026-05-30

Oettle ruth

Microsoft Word - Thesis of Ruth Oettle The Environment for sale? The examination of the critical features of a third‐party in facilitating a transaction in the market for environmental offsets. Ruth Oettle ruth.oettle@gmail.com 25 May 2008 Submitted in partial fulfilment of the requirements for the International Master’s Programme in Environmental Studies and Sustainability Science (LUMES), Lund U

https://www.lumes.lu.se/sites/lumes.lu.se/files/oettle_ruth.pdf - 2026-05-30

Seminar: Shaping Shared Spaces – Public Art Between Idea, Site, and Practice at Kv.Paradis, Lund University Campus

28 maj 2026 17:00 till 19:00 | Seminarium Welcome to an evening seminar on art in campus environments 17:00 Opening Annie Lindberg, Director of Skissernas Museum, welcomes guests.Introduction Marcus Rancken, Strategic Property Developer and Head of Art, and Lotta Mossum, Head of the Art Unit, introduce the collaboration between the Public Art Agency Sweden and Akademiska Hus.Background Moderators

https://www.medarbetarwebben.lu.se/evenemang/seminar-shaping-shared-spaces-public-art-between-idea-site-and-practice-kvparadis-lund-university - 2026-05-30

Musik och Ljudlandskap

Hur musik och musikskapare påverkats av ljudmiljöer 2016-05-27 genomförde Ljudmiljöcentrum det tvärvetenskapliga symposiet "Musik och Ljudlandskap - hur musik och musikskapare påverkats av ljudmiljöer" Musik & ljudlandskap - ett tvärvetenskapligt symposium om hur musik och musikskapare påverkats av ljudmiljöer MEDVERKANDE:Gunnar Jinmei Linder - doktor i japanologi och mästarexamen som Shakuhachi-s

https://www.lmc.lu.se/aktiviteter/aktiviteter-2016/musik-och-ljudlandskap - 2026-05-29

Cancer

På 1950-talet var en cancerdiagnos nästan en dödsdom – inte ens var tredje person som insjuknade överlevde sin sjukdom. Sedan dess har mycket hänt och prognosen för många cancerdiagnoser har förbättrats avsevärt. Men fortfarande återstår utmaningar att lösa för både de drabbade och deras närstående. Cancer uppstår när normala celler i vävnader av olika anledningar förändras och börjar dela sig oko

https://www.medicin.lu.se/bidratillforskning/angelagen-forskning-att-stodja/cancer - 2026-05-30

Microsoft Word - TeriSchamp-Bjerede-WorkExperienceDocumentation.doc

Microsoft Word - TeriSchamp-Bjerede-WorkExperienceDocumentation.doc Teri Schamp-Bjerede 2013-09-01 1 / 11 Documentation: Work Experience and Merits Teri Schamp-Bjerede (2013-01) Teri Schamp-Bjerede Hinsegatan 4 37433 Karlshamn Sweden Teri-LSB Rectangle Teri-LSB Rectangle Teri-LSB Rectangle Teri-LSB Rectangle Teri-LSB Rectangle Teri-LSB Rectangle Teri Schamp-Bjerede 2013-09-01 2 / 11 Table of Conte

https://www.sol.lu.se/media/documents/persons/TeriSchampBjerede/TeriSchamp_Bjerede_WorkDocumentation.pdf - 2026-05-28

Recommendations-Ai-eng-correct-logo

Namnlös Visiting address Tycho Brahes väg 1, Lund SWEDEN Website www.lusem.lu.se LUSEM AI Commit tee Recommendations for mandatory information on Canvas course pages regarding student use of generative artificial intelligence The purpose of these recommendations is to assist department leadership groups at Lund University School of Economics and Management (LUSEM) in determining the mandatory info

https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2024-09/recommendations-Ai-eng-correct-logo.pdf - 2026-05-30