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Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, inflammation, and infection. A majority of the identified proteinases converted IgG to F(ab')(2), and a consistent feature of their action was a transient

The insecurity of trafficking in international law

The present chapter inquires into to the definition of trafficking in the 2000 Trafficking Protocol. The concept of trafficking seems to offer a self-evident point of departure to broach inequality and migration in the international domain. It emphasises the inequality between trafficker and the trafficked person, and States task themselves to side with the latter - and weaker - party in that rela

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Je m'appelle Laruda, j'ai quinze ans et ma marraine m'emmène passer des vacances en Italie. Mais mes parents s'inquiétent peut-être donc je vais leurs téléphoner. - Allo, papa, c'est Laruda, ca va? - Oui et toi? - Oui très bien c'est super! - Racconte moi un peu ce que tu fais. - Voilà, lorsque tu m'as laissé chez tata, elle m'a préparé un chocolat chaud que l'on a bu en regardant la carte qui nou

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/controle/Edna.txt - 2026-05-14

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This paper presents the cultural and archaeological context of the human fossil bones from Muierii Cave, dated by us to the age of 30 150 ± 800 14C years BP (Before Present) or 34 810 ± 927 cal years BP (calibrated years Before Present), and from Cioclovina Cave, dated to the age of 29 000 ± 700 14C years BP or 33 540 ± 832 cal years BP, in the Southern Carpathians. These are among the most ancien