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Brain-derived neurotrophic factor (BDNF) and other neurotrophins are believed to play an important role in affective disorders. In this study we investigated plasma-BDNF response during an incremental exercise test in 18 patients suffering from moderate major depressive disorder (MDD) and 18 controls. The patients were not treated with antidepressants or neuroleptics. Possible associations between
Importance: This follow-up study of extremely preterm (EPT) children (<27 weeks' gestational age [GA] at birth) revealed major eye and visual problems in 37.9% (147 of 388) of all EPT infants and in 55.4% (67 of 121) of the most immature subgroups at 6.5 years of age. These major eye and visual problems were strongly associated with treatment-requiring retinopathy of prematurity (ROP).Objectives:
In order to reduce the vibration transmission in multi-storey wood buildings, it is common to insert viscoelastic elastomer materials between parts of the buildings. The studies presented here investigate to which extent different design choices for the elastomer layers affect the isolation of low-frequency vibrations (0-100 Hz). A finite element model of two storeys of a multi-storey wood buildin
The purpose of this book chapter is to investigate to what extent technical function can be protected under European Union (EU) copyright law. Technical function has been explicitly excluded under other regimes of protection in the Union, for example, trademark and design protection law, to avoid overlap (also known as cumulation) between these regimes and patent law. No such statutory provisions
Electrical brain activity and eye movements were recorded in 10 intact and 6 unilaterally labyrinthectomized rabbits, each with implanted electrodes. The frequency of optokinetic nystagmus (OKN) and a 10-second aggregate of theta waves in the dorsal hippocampus were determined after exposure of the animals to sound, vibration and optokinetic stimulation. Each stimulus used caused significant incre
Background: The prognosis of Alzheimer’s disease (AD) might be influenced by many sociodemographic and clinical factors. Previous studies have investigated the main effects of critical predictors but few have analyzed potential interactions. We have studied the long-term cognitive outcome, nursing home placement (NHP) and mortality by interactions between factors in cholinesterase inhibitor (ChEI)
PURPOSE: The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. METHODS: In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief a
Elevated plasma cytokines is a common finding in Major Depressive Disorder (MDD), although not consistent. It is currently not known whether the inflammatory changes are confined to any specific subgroup of depressive patients. We here analyzed three inflammatory markers in suicidal and non-suicidal depressive patients, as well as healthy controls. Plasma interleukin (IL)-2, IL-6 and tumor necrosi
International oil prices have been fluctuating a lot since decades. Since oil is an important component influencing global indicators, it is also important to evaluate to what extent consumer spending is affected in the aftermath of oil price shocks. Thus the paper addresses whether international oil price change has any impact on consumer spending in the long and short run. To conduct this study,
I denna uppsats undersöker jag Scanlons värdeteori, med fokus på hans syn på intrinsikalt värde, och då framför allt frågan huruvida människolivet kan sägas ha intrinsikalt värde. Genom att först grundligt presentera Scanlons värdeteori – hans hänskjutande redogörelse för värde (eng. Buck-Passing) - och sedan släppa fram kritiska röster, resonerar jag mig fram till en grund att stå på i denna värd
Purpose The purpose of this thesis is to study if and how institutional investors have any impact on shareholder value and operating performance on the Swedish market. The tested explanatory variables are institutional investors grouped in different ways depending on their attributes, firm size, board size and board structure, leverage, firm size, share turnover and stock volatility. Theoretical
Förevarande uppsats undersöker EU-domstolens praxis avseende värdeöverföringar mellan originaltillverkare av läkemedel och generikaföretag i samband med patentförlikningar (så kallade ‘RPPSs’) för att urskilja under vilka förutsättningar ett sådant förfarande utgör en syftesöverträdelse. Analysen visar att EU-domstolens avgöranden Generics och Lundbeck förtydligar bedömningen av mer okompliceradeThis thesis examines the CJEU’s case law on value transfers between originator and generic undertakings, in the context of patent settlements, to ascertain the criteria for determining when such a practice amounts to a restriction of competition by object. The thesis finds that the CJ’s rulings in Generics and Lundbeck clarifies the treatment of more straightforward RPPSs and follows established
Det råder en global kontinuerlig teknikutveckling som präglar internet med nya innovationer. Många onlinetjänster på internet bedriver sina verksamheter med hjälp av datainsamling av de digitala konsumenterna. Teknikutveckling kräver en insats från både onlinetjänster som behöver vara fortsatt anpassningsbara och digitala konsumenter som behöver begripa vilka konsekvenser utveckling har. Datainsam
Income Tax-deduction for commuting expenses has been criticised and discussed for a long time without having reached any conclusions or reformations. Critical opinions in the debate are that a reformation would disfavour taxpayers living in the countryside with no options except car commuting and decreasing size of labour market regions. At the same time tax evasion is a huge problem because taxpa
Obesity levels in developing countries are increasing at an alarming rate, while “old” problems such as hunger and undernutrition still persist, creating a paradoxical situation of a double burden of malnutrition. Intertwined with new sustainability challenges such as climate change and land degradation, food, health and sustainability are interconnected in a complex web of relationships, spanning
