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Objective: Drug eluting stents (DES) might improve the results of stenting in the femoropopliteal (FP) segment, but randomized data between DES and BMS in the treatment of patients with chronic limb threatening ischemia (CLTI) is lacking. The aim of this study was to perform a randomized comparison, between DES and bare metal stent (BMS) implantation in a subgroup of CLTI patients with lesions in
This paper explores whether Ethiopia's rapid economic growth is transformative enough for the country to eventually catch up with high-income countries. It does so by exploring the change and continuity of four elements of social capability from 1950 to 2020: structural transformation, economic inclusion and the state's autonomy and accountability. It finds that Ethiopia's social capability modest
Background: A substantial proportion of women with breast cancer (BC) experience a wide range of long-term persistent and troublesome side effects related to the disease and its treatment. The ReScreen randomized controlled trial is conducted aiming to evaluate the effect of early screening of distress followed by individualized rehabilitation after primary BC treatment.Purpose: To examine recruit
PURPOSE: Intrauterine undernutrition is associated with increased risk of type 2 diabetes. Children born premature or small for gestational age were reported to have abnormal retinal vascularization. However, whether intrauterine famine act as a trigger for diabetes complications, including retinopathy, is unknown. The aim of the current study was to evaluate long-term effects of perinatal famine
Background and aims: After aortic coarctation (CoA) repair, patients still suffer from cardiovascular complications. The aim of this study was to measure cardiovascular markers, intima-media thickness (IMT) and plaques in controls and patients with CoA. Methods: Sixty-four patients with CoA (66% male, mean age 48 ± 15 years) and controls (54% men, mean age 47 ± 16 years) underwent ultrasound of th
Transient global ischaemia induces the expression of immediate early genes. Using in situ hybridization, the expression of c‐fos, fosB, fra‐1, fra‐2, c‐jun and junB was studied after 15 min of normothermic and hypothermia (33°C) transient forebrain ischaemia in the rat, induced by common carotid occlusion combined with systemic hypotension. Two phases of induction of the immediate early genes were
Disruption of intracellular calcium homeostasis is thought to play a role in neurodegenerative disorders such as Huntington's disease (HD). To study different aspects of putative pathogenic mechanisms in HD, we aimed to establish an in vitro model of calcium-induced toxicity in striatal neurons. The calcium ionophore A23187 induced a concentration- and time-dependent cell death in cultures of embr
Mitochondria from different regions of the brain were prepared, and the activation of the mitochondrial permeability transition (MPT) by calcium was investigated by monitoring the associated mitochondrial swelling. In general, the properties of the MPT in brain mitochondria were found to be qualitatively similar to those observed in liver and heart mitochondria. Thus, swelling was inhibited by ade
The purpose of the present study was to examine the effect of blockade of N-methyl-D-aspartate (NMDA) receptors on the depolarization associated with severe hypoglycemia, which is commonly preceded by one or a few transient depolarizations reminiscent of cortical spreading depression (CSD). In the cerebral cortices of rats [K+](e) and [Ca2+](e) were measured with ion-selective microelectrodes. NMD
The subcellular distribution of PKC(α) and PKC(γ) was studied in homogenates of cerebral cortex from rats subjected to 10 and 15 min of ischemia and 15 min of ischemia followed by 1 h, 6 h, 24 h, 48 h, and 7 days of reperfusion. During ischemia no significant changes in the levels of PKC (α) were seen. During the first hour of reperfusion, a transient 2.5-fold (P < 0.05) increase in PKC(α) levels
Förbudet mot köp av sexuella tjänster har varit i kraft i 16 år. Den debatt som åtföljt lagstiftningsarbetet kan dock sägas ha pågått under närmare 40 år. Det är en debatt med starka ideologiska förtecken och det är tydligt att prostitution är en fråga som inte lämnar någon oberörd. Uppsatsens syfte är utreda vilka ideologiska värderingar och skyddsintressen som återfinns i lagstiftarens syn på p
Omfattande behandlingsforskning har visat att mindfulnessbaserade interventioner är effektiva för att minska lidande hos smärtpatienter. Hur detta kan förklaras är dock ännu inte klarlagt. I den här kvasiexperimentella studien ville vi undersöka sambandet mellan mindfulnessförmåga, experentiellt undvikande och smärtupplevelse. Mer specifikt ville vi ta reda på om experentiellt undvikande kunde förExtensive research has shown that mindfulness-based interventions are effective when it comes to reducing experiences of pain in patients with chronic pain. However, the mechanisms behind the effect have not yet been fully clarified. The aim of this quasi-experimental study was to examine the correlation between mindfulness skills, experiential avoidance and the experience of pain. More specifical
In this work, surface enhanced Raman spectroscopy (SERS) was combined with dielectrophoresis (DEP) to realize a controllable in situ detection method of enhanced Raman signals from molecules in suspension environment. Polymer beads coated with gold nanoparticles were prepared as SERS ‘hot spot’ substrates. Several DEP electrode designs were evaluated and the stripe electrode succeeded in manipulat
B-uppsatsen, Det vita snuset, wellness och femininiteter - En semiotisk bildanalys av hur wellness och femininiteter framställs och konstrueras för att marknadsföra vitt snus på Velo, ZYN och Loops Instagram-konton, är skriven av Hanna Thomasson Dykert och Tilde Strömberg Rye i ämnet Medie- och Kommunikationsvetenskap, vid institutionen för kommunikation och medier, Lunds universitet. Uppsatsens h
Det finns olika teorier kring vem som bevisbördan ska falla på inom tvistemål när det råder oenighet kring huruvida ett visst rättsfaktum ligger för handen. Bevissäkringsteorin är en av dessa. Bevissäkringsteorin innebär att bevisbördan läggs på den som har haft det lättast för att säkra bevisning. Mot bevissäkringsteorin konkurrerar de materiella bevisteorierna. Dessa teorier förespråkar att beviThere are different theories regarding who should carry the burden of proof within civil cases when there is controversy regarding whether or not a certain fact is at hand. The theory of securing evidence is one of these. The theory of securing evidence states that the burden of proof should be placed on whomever has an easier time of securing evidence. The material theories of evidence compete wi
Purpose of the Review: Recent insights into extracellular vesicles (EVs) derived from platelet (PC) and red blood cell concentrates (RBC), which form during blood product processing and storage. Recent Findings: EVs impact transfusion outcomes by modulating immune and inflammatory responses. Acting as lipid mediators and expressing adhesion molecules, EVs contribute to immune signaling via cytokin
HfO2, one of the most common materials in resistive switching devices, can stabilize in a ferroelectric orthorhombic phase, enabling two nonvolatile polarization states via oxygen displacement in the unit cell. Under certain conditions, ferroelectric and resistive switching can coexist, independently addressable, within one device. This study employs operando spectroscopic analysis to elucidate th
