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Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
Central to the field of agrarian political economy, is rural development and capitalism’s advancement in the countryside and its consequences for the peasantry, ‘the agrarian question’. With the present case study, I examine the interplay between social relations of production and agrarian change in eastern Bolivia. Using the case study of Ramada, a small indigenous community, this dissertation in
Lagen om hemlig dataavläsning trädde i kraft den 1 april 2020. Lagen innebär att brottsbekämpande myndigheter, utöver säkerhetspolisen, kan få tillgång till innehållet i den enskildes mobiltelefon och dator. Särskilt vid tvångsmedelslagstiftning är det viktigt att lagstiftaren förhåller sig till de rättsliga principer och begrepp som gäller på ett korrekt vis. Denna uppsats ämnar att kritiskt graThe Secret data interception law was implemented on 1 of April, 2020. The law allows law enforcement authorities, not just the security police, to gain access to information from an individuals' mobile phone and computer. In the case of coercive measures legislation, it is important that the legislator relates to the corresponding legal principles and concepts in a correct way. This essay in
Informal green spaces are “small green areas” which are some square meter plots along streets or in junctions, in front of public or private buildings. Informal urban green space become or remain in neglected condition due to the lack of capacity of the municipality to maintain them. Further, there is a lack of responsibility, competency and motivation of the residents to voluntarily take care of
Opening up your home to unaccompanied young refugees : A study about voluntary foster parents, their motives and commitment Migration politics in Sweden has shifted to a more restrictive stance in the past few years. Unaccompanied asylum-seeking minors are an especially vulnerable group that has been affected by this. Many of them find themselves in a difficult position when they turn 18, when th
This study aims to examine how local governments originated from the global South, through Urban Food System Strategies (UFSS), are realizing global sustainability priorities as outlined by the Sustainable Development Goals (SDGs). This study is based on the policy analysis of three Latin American UFSS, with the aim to detect synergies and connections between the UFSS and the SDGs. The primary c
The aim of this doctoral thesis is to contribute to the debate on the importance of diet and disease in explaining the mortality decline and the general literature of the long-term effects of early life conditions. Using individual-level data from Southern Sweden for 1813 to 1968, this work measures the impacts of grain prices during the foetal stage and infant mortality rates during the year of b
Background: With an increased life expectancy for the general population as well as for those ageing with chronic diseases, there are major challenges to the affected individuals and their families, but also to health care and societal planning. Most important, an increasing proportion of older people remain living in their ordinary homes despite health decline and disability. However, little is k
The results of a round robin test on isothermal (heat conduction) calorimetry are presented. A total of 18 participants using three types of instruments conducted 3-day measurements of the hydration of one rapidly hardening Portland cement and one slag-containing cement. The results confirm that isothermal calorimetry is a suitable method for the determination of heat of hydration. As a part of th
By employing metal salts in dilute-acid pretreatment the severity can be reduced due to reduced activation energy. This study reports on a dilute-acid steam pretreatment of spruce chips by addition of a small amount of ferrous sulfate to the acid catalyst, i.e., either SO(2), H(2)SO(3) or H(2)SO(4). The utilization of ferrous sulfate resulted in a slightly increased overall glucose yield (from 74%
Background: Voltage-dependent K+ channels (Kv) mediate repolarisation of beta-cell action potentials, and thereby abrogate insulin secretion. The role of the Kv1.1 K+ channel in this process is however unclear. We tested for presence of Kv1.1 in different species and tested for a functional role of Kv1.1 by assessing pancreatic islet function in BALB/cByJ (wild-type) and megencephaly (mceph/mceph)
This paper should be read as addendum to Dieckmann et al. (J Theor Biol 241:370-389, 2006) and Parvinen et al. (J Math Biol 67: 509-533, 2013). Our goal is, using little more than high-school calculus, to (1) exhibit the form of the canonical equation of adaptive dynamics for classical life history problems, where the examples in Dieckmann et al. (J Theor Biol 241:370-389, 2006) and Parvinen et al
Background: Use of three-dimensional (3D) color volume-rendered (VR) images has been reported to be more time-efficient compared to that of cross-sectional computed tomography (CT) images for the diagnosis of peroneal tendon dislocation. However, the diagnostic performance of this technique has not been studied. Purpose: To test diagnostic accuracy of 3D color VR CT images of ankle for peroneal te
Objective To develop a disease activity index for patients with primary Sjogren's syndrome (SS): the European League Against Rheumatism (EULAR) Sjogren's syndrome disease activity index (ESSDAI). Methods Thirty-nine SS experts participated in an international collaboration, promoted by EULAR, to develop the ESSDAI. Experts identified 12 organ-specific 'domains' contributing to disease activity. Fo
Introduction. The aim of this model study was to estimate and compare the risk of radiation-induced adverse late effects in pediatric patients with medulloblastoma (MB) treated with either three-dimensional conformal radiotherapy (3D CRT), inversely-optimized arc therapy (RapidArc ® (RA)) or spot-scanned intensity-modulated proton therapy (IMPT). The aim was also to find dose-volume toxicity param
