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Background: Total hip joint replacement (THR) is a high volume, effective intervention for hip osteoarthritis (OA). However, indications and determinants of outcome remain unclear. The 'EUROHIP consortium' has undertaken a cohort study to investigate these questions. This paper describes the variations in disease severity in this cohort and the relationships between clinical and radiographic sever
Radiochromic film, polymer gel and radiochromic plastic are three different kinds of dosimeters developed for radiation therapy and suitable for optical readout. In this study, different optical CT scanners are used to scan the dosimeters to find out if they could be used as multi-purpose scanners, i.e. for readout of the different kinds of dosimeters. Promising results are found but further devel
Although for large area detectors it is crucial to find an alternative to detect thermal neutrons because of the He-3 shortage, this is not the case for small area detectors. Neutron scattering science is still growing its instruments' power and the neutron flux a detector must tolerate is increasing. For small area detectors the main effort is to expand the detectors' performances. At Institut La
Stretch of vascular smooth muscle stimulates growth and proliferation as well as contraction and expression of contractile/cytoskeletal proteins, all of which are also regulated by calcium-dependent signals. We studied the role of the calcium- and integrin-activated proline-rich tyrosine kinase 2 (PYK2) in stretch-induced responses of the rat portal vein loaded by a hanging weight ex vivo. PYK2 ph
This article examines the way in which classification of financial instruments as debt or equity has developed in the Swedish income taxation system over the past 25 years. Although the structure of the tax system is based on the assumption that debt instruments are financial instruments with low risk, legal developments have not shared that assumption, resulting in several types of high-risk deri
I artikeln presenteras ett projekt om forskares behov av stöd, genomfört 2012, inom biblioteksnätverket Lunds universitets bibliotek (LUB). Projektet består av a) en litteraturöversikt med fokus på definitioner av och exempel på forskarstöd samt vilka behov och erfarenheter forskare själva har av forskarstöd, b) en enkätundersökning av befintlig forskarservice från biblioteken inom (LUB), ett deceThis article presents a 2012 project on researchers’ need of support at Lund University Libraries (LUB). The project was three folded with the object to identify areas where the present research support services ought to be developed and strengthened. The project contains a) a literature review focusing on definitions and examples of research support services as well as researchers’ needs and expe
Mapping coastal inlets and their catchment areas is essential for management of the coastal zone. The coastal inlets are important channels of exchange of nutrients, water and sediment between the land and sea. They are also important elements of the coastal hydrological system and play a vital role in controlling the water flow into the sea during floods. Blocking of the coastal inlets is one of
Genome-wide association studies have recently identified at least 15 susceptibility loci for systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from 2,466 regions that showed nominal evidence of association to SLE (P < 0.05) in a genome-wide study and genotyped them in an independent sample of 1,963 cases and 4,329 controls. This replication effort identified fiv
Four systems for household food waste collection are compared in relation the environmental impact categories eutrophication potential, acidification potential, global warming potential as well as energy use. Also, a hotspot analysis is performed in order to suggest improvements in each of the compared collection systems. Separate collection of household food waste in paper bags (with and without
In this study, the production of enantiomerically pure (1R,4S,6S)-6-hydroxy-bicyclo[2.2.2]octane-2-one ((-)-2) through stereoselective bioreduction was used as a model reaction for the comparison of engineered Saccharomyces cerevisiae and engineered Escherichia coli as biocatalysts. For both microorganisms, over-expression of the gene encoding the NADPH-dependent aldo-keto reductase YPR1 resulted
Background: We recently reported (Curr Biol 22:683-688, 2012) that the eyes of giant and colossal squid can grow to three times the diameter of the eyes of any other animal, including large fishes and whales. As an explanation to this extreme absolute eye size, we developed a theory for visual performance in aquatic habitats, leading to the conclusion that the huge eyes of giant and colossal squid
Acute management of traumatic brain injury (TBI), in particular mild TBI, focuses on the detection of the 5-7 % who may be harboring potentially life-threatening intracranial hemorrhage (IH) using CT scanning. Guidelines intending to reduce unnecessary head CT scans using available clinical variables to detect those at high IH risk have shown varying results. Recently, the Scandinavian Neurotrauma
Study objectives: A method for medication reconciliation that reduces medication errors and healthcare contacts when a patient is discharged from hospital, LIMM-DI (Lund integrated medicines management-discharge information) had been previously developed by the authors. LIMM-DI is structured information written for the patient and sent to the next caregiver. In this study, the use (implementation
A series of tests were performed to explore the limits of two capacitive level sensors using the principle of parallel finger layout (sometimes called comb fingers) for sensing. The goal was to present a decision basis for Baxter to use when choosing a sensor to implement in their next generation hemodialysis machine. The devices under tests were 1) sensor type A: developed in-house and 2) sensor
The municipality of Helsingborg, located in Scania implemented the Livskvalitetsprogrammet (The programme of living quality) in 2016. The goal with the programme is to unite sustainable development and quality of life. The work with the programme will continue towards 2024. I was given the assignment to research the knowledge of the programme throughout the organisation. The questionnaire is to be
Mountains provide a variety of ecosystem services, such as drinking water, which sustains not only mountain communities but also people living further downstream. While climate change threatens most ecosystems, its negative impacts are up to three times greater in high altitudes. As well as changing the water cycle this further accelerates climate change. Although they contribute comparably little
This study aims to examine how the sensitivity for macroeconomic announcements surprises changes for the exchange rate in terms of a crisis. Previous research has been biased for U.S announcements and their relation towards emerging market, which has shown that U.S announcements affect more than the domestic. It also suggests that business cycle and uncertainty affect and increase the reaction for
Medborgarnas politiska delaktighet har en central roll i en god demokrati. För att uppnå politiskt deltagande, främst bland de grupper i samhället som sällan deltar, använder många svenska kommuner sig idag av medborgardialog. Medborgardialog innebär att politiker och tjänstemän bjuder in till samtal för att diskutera olika frågor som berör medborgarnas intressen. Denna uppsats är en normativ stud
Statsansvaret för folkmord har en jus cogens status i internationell sedvanerätt och utgår från den generella hänförbarhetsregeln: huruvida de inom staten aktiva personer eller grupper är verksamma, eller åtminstone kan anses vara verksamma å statens vägnar är avgörande för att staten kan hållas ansvarig. För att icke-statliga aktörer kan vara hänförliga till staten måste förhållandet dem emellan State responsibility for commission of genocide has a jus cogens status in customary international law and is based on the general rule of attribution: whether the persons or groups acting within the State are acting, or at least can be treated as acting on behalf of the State is key for State responsibility to arise. For non-state actors to be attributable to the State the relationship between th
Uppsatsens syfte är att undersöka huruvida kulturegendom tillmäts ’tillräckligt skydd’ av internationell rätt i väpnade konflikter, med betoning på den juridiska grunden för att åtala förstörelse av kulturarv som ett krigsbrott under internationell straffrätt. Jag undersöker hur de mest relevanta traktaterna i internationell rätt har uppstått sedan antagandet år 1954 av Haagkonventionen för skyddThe purpose of this thesis is to examine whether cultural property is attributed ‘sufficient protection’ by international law in armed conflicts, with an emphasis on the legal basis for prosecuting its destruction as a war crime under international criminal law. I research how the most relevant treaties in international law have emerged since the adoption of the Convention for the Protection of Cu
