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Solving Exact Cover Instances with Molecular-Motor-Powered Network-Based Biocomputation

Information processing by traditional, serial electronic processors consumes an ever-increasing part of the global electricity supply. An alternative, highly energy efficient, parallel computing paradigm is network-based biocomputation (NBC). In NBC a given combinatorial problem is encoded into a nanofabricated, modular network. Parallel exploration of the network by a very large number of indepen

Hand function 6 weeks following non-surgically treated proximal phalangeal fractures and factors associated to upper extremity disability

Purpose: To describe hand function, and investigate adherence to a rehabilitation protocol and factors associated with upper extremity disability in non-surgically treated proximal phalangeal fractures. Material and methods: In a prospective cohort study, 86 patients (58 women, mean age of 49 years) were assessed at cast removal and 6 weeks follow-up. Adherence was registered in a diary. Factors p

Lack of autoantibodies against collagen and related proteins in collagenous colitis

INTRODUCTION: Collagenous colitis (CC) is a common cause of chronic diarrhea and is characterized by a subepithelial thickened collagen layer in the colonic mucosa. It shares many of the characteristics found in autoimmune diseases, but no autoantibodies have been identified. In CC, an imbalance in collagen turnover is evident. The purpose of the present study was to investigate whether any collag

BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells

The cytokine TGFβ1 induces epidermal Langerhans cell (LC) differentiation from human precursors, an effect mediated through BMPR1a/ALK3 signaling, as revealed from ectopic expression and receptor inhibition studies. Whether TGFβ1‒BMPR1a signaling is required for LC differentiation in vivo remained incompletely understood. We found that TGFβ1-deficient mice show defective perinatal expansion and di

Lung Function and Health Status in Individuals with Severe Alpha-1-Antitrypsin Deficiency at the Age of 42

Background: Severe hereditary alpha-1-antitrypsin deficiency (AATD) is a known risk factor for the early development of pulmonary emphysema and COPD, especially in smo-kers. By the Swedish national screening programme carried out from 1972 to 1974, a cohort of individuals with severe (PiZZ) AATD was identified and has been followed up regularly. The aim of this study was to investigate health stat

Tuberculosis Infection in Women of Reproductive Age : A Cross-sectional Study at Antenatal Care Clinics in an Ethiopian City

Background: Knowledge on tuberculosis (TB) infection epidemiology in women of reproductive age living in TB-endemic areas is limited. We used a composite definition of TB infection in a cohort of pregnant women recruited in an Ethiopian city as a model for TB exposure patterns, and to identify factors associated with TB infection. Methods: Women seeking antenatal care at public health facilities u

Real-Time Emission and Exposure Measurements of Multi-walled Carbon Nanotubes during Production, Power Sawing, and Testing of Epoxy-Based Nanocomposites

The use of manufactured nanomaterials is increasing globally. Although multi-walled carbon nanotubes (CNTs) are used in a wide range of applications, only limited data are available on emissions and exposures during CNT composite production. No exposure data using portable aethalometers in the personal breathing zone (PBZ) to monitor occupational exposure to CNTs have yet been published. The aim o

Virtual clinical trial of simultaneous digital breast tomosynthesis and mechanical imaging: : model calibration and the effect of tumor depth

Simultaneous Digital Breast Tomosynthesis (DBT) and mechanical imaging (MI), called DBTMI, is a novel breast imaging method aimed at improving sensitivity and specificity of breast cancer screening. DBTMI combines improved cancer detection by three-dimensional DBT imaging, with the analysis of local stress over the compressed breast by MI, which can reduce false positive findings. The MI signal is

Regional differences in treatment and outcome for myeloma patients in Sweden : A population based Swedish myeloma register study

Background: We wanted to evaluate if health care for multiple myeloma (MM) patients is equal in different regions of Sweden. Aim: To study differences in survival for MM depending on health care region and early use of modern treatment. Methods and results: Data from the Swedish Myeloma Register from patients diagnosed between 2008 and 2017 was used. Cohorts were defined by the six healthcare regi

Nuclear expression of pSTAT3Tyr705 and pSTAT3Ser727 in the stromal compartment of localized hormone-naïve prostate cancer

Background: The signal transducer and activator of transcription 3 (STAT3) is involved in the progression of different tumors including prostate cancer (PCa). The expression of STAT3 in benign and malignant epithelium has been described previously but it has not been described in the stromal compartment. The aim of the present study was to evaluate the nuclear expression and prognostic value of di

Nämndemannasystemet ur ett rättssäkerhetsperspektiv

The focus of my thesis has been the Swedish lay judges. My purpose has been to examine the Swedish system of lay judges and furthermore study it in relation to legal certainty. My major problem statement has been: In accordance with legal certainty, what advantages and disadvantages can be seen with the system of lay judges? The Swedish lay judges participate primarily in district and appellate c

Immunity of Former High Ranking State Officials for International Crimes before Foreign National Courts

The purpose of the thesis is to examine to what extent former high ranking state officials are immune for international crimes before foreign national courts. Historically national courts have recognized absolute immunity, but this approach has gradually to some extent changed after the establishment of international tribunals and the International Criminal Court in which official capacity is irre

Yes we can - stop keystone pipeline

The aim of this thesis is to gather an understanding of the creation of unlikely alliances within the environmental movement as a social movement. This is done in turn done by looking at the resistance among the environmental movement as well as grassroots organizations that arose around the proposal to build a pipeline called Keystone XL made by the Canadian oil company TransCanada in 2008. The f

Ansvar för att skapa hållbarhet : en begreppsanalys av ansvar i den svenska modeindustrins hållbarhetsredovisningar

My thesis ’’Responsibility to create sustainability – a concept analysis of responsibility in the sustainability reports of the Swedish fashion industry’’, investigates Hennes & Mauritz and Filippa Ks view of the concept responsibility in sustainability reports, be- fore and after the adoption of The Sustainable development goals. The purpose of this study is to uncover if the enterprises view

Spela för att läsa! En studie om GraphoLearns effekter på avkodningsförmåga hos barn i åldrarna 6 till 7 år

Syfte: Huvudsyftet med studien var att undersöka den phonicsbaserade lärappen GraphoLearns effekter på avkodningsförmågan hos svensktalande barn i tidig läsutveckling. Sekundärt var syftet att undersöka huruvida träning med GraphoLearn kan påverka hjärnstruktur. Studien kan betraktas som en pilotstudie för ett större pågående projekt. Metod: Fjorton deltagare i åldrarna 6 till 7 år inkluderades. S

”Hjärtat slår och det känns som dom håller på att dö eller svimma” : en kvalitativ studie av hur lärare kan arbeta med talrädsla vid muntliga framställningar i svenskämnet i gymnasieskolan

I denna uppsats står rädsla för att tala i fokus. Talrädsla belyses med retorikämnet som grund, och studien tar avstamp i den svenska gymnasieskolan. Syftet med studien är att ta fram ett handfast material för hur svensklärare på gymnasieskolan kan arbeta med talrädda elever. För att uppnå syftet genomförs en litteraturstudie, där handböcker som behandlar området talrädsla studeras. I dessa handböIn this study, language anxiety is in focus. Language anxiety is studied with the subject of rhetoric as a basis, and the study is based on the Swedish upper secondary school. The aim of the study is to produce a solid material for how Swedish teachers at upper secondary school can work with students with language anxiety. In order to achieve this purpose, a literature study is carried out, in whi