Filtyp
By combining ultrashort laser pulses with PEEM, time-resolved photoemission electron microscopy (TRPEEM) provides a powerful approach for investigating ultrafast charge carrier dynamics with simultaneous femtosecond temporal resolution and nanometer spatial precision. It has evolved into a versatile methodto study a wide range of phenomena, including charge carrier dynamics, surface plasmons, scat
Two-level systems (TLSs) are the basic units of quantum computers but face a trade-off between operation speed and coherence due to shared coupling paths. Here, we investigate a TLS given by a singlet-triplet (ST+) transition. We identify a magnetic-field configuration that maximizes dipole coupling while minimizing total dephasing, forming a compromise-free sweet spot that mitigates this fundamen
BackgroundAntibiotics are handled in large amounts at hospitals at many different wards due to the wide range of bacterial infections that are treated. Unnecessary use and occupational exposure to antibiotics should be avoided due to the risk of bacterial resistance development and adverse health effects including skin and respiratory hypersensitivity reactions in persons handling these drugs.Obje
Developing novel organic photovoltaic materials for organic solar cells (OSCs) requires precise characterization of their charge transfer states to optimize the photoinduced charge transfer mechanisms within the photoactive layer. The microscopic photoelectric properties of the S-shaped (DYA-I-S) and O-shaped (DYA-I-O) conformations of dimeric small molecule acceptors (DSMAs) are analyzed through
Magic Angle Spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is limited in spectral resolution by the spinning frequency of rotors that hold the analyte. Traditional yttria-stabilized zirconia (YSZ) rotors have mechanical constraints that typically limit spinning frequencies of 0.7 mm rotors to ωr/2π ∼ 110 kHz. These frequencies are not sufficient to achieve resolution comparable to th
With the development of ultrafast laser technology, time-resolved spectroscopy has become an essential tool to study the microscopic photophysical mechanisms on ultrafast time scales in the field of solar energy conversion and utilization. Transient absorption spectroscopy (TAS), as an essential technology for studying photoinduced ultrafast electron transfer and photo-induced carrier dynamics, ha
OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of immunosuppressants with or without corticosteroids compared to corticosteroid monotherapy for the treatment of IgG4-related disease in people 18 years or older.
Coherent extreme ultraviolet (XUV) radiation can be generated in a tabletop configuration via high-order harmonic generation (HHG) in gases. While HHG is inherently inefficient, increasing the conversion efficiency (CE) is crucial for many applications, such as coincidence spectroscopy [1] and coherent imaging [2], which require high XUV throughput. Previous calculations suggest that one way to im
Intense ultrashort-pulsed laser systems based on Ti:sapphire chirped pulse amplifiers (CPA) operating at 800 nm have been a workhorse of ultrafast science for several decades. More recently, driven by the progress in laser technology, sources with central wavelengths further in the infrared have emerged as powerful tools, in particular to generate soft X-ray (SXR) radiation via high-harmonic gener
Background. Post-traumatic chondral and osteochondral lesions can be treated with autologous chondrocyte implantation (ACI), but the high cost of autologous cell expansion under strict Good Manufacturing Practice (GMP) regulations limits patient access. Stem cell–based advanced therapy medicinal products (ATMPs) offer more cost-effective alternatives, with human induced pluripotent stem cells (iPS
Polyamines are regulatory metabolites with key roles in transcription, translation, cell signalling and autophagy1. They are implicated in multiple neurological disorders, including stroke, epilepsy and neurodegeneration, and can regulate neuronal excitability through interactions with ion channels2. Polyamines have been linked to pain, showing altered levels in human persistent pain states and mo
Aim: Periodontitis proxy variables enable an expansion of periodontal research. The study aimed to estimate the validity of questionnaire items and registry data in relation to Stage III–IV periodontitis and having 50% bone loss. Methods: Malmö Offspring Dental Study (MODS) participants (995) filled out questionnaires and underwent periodontal and panoramic radiography examinations. The questionna
Leucine-rich repeat containing 15 (LRRC15) has emerged as an attractive biomarker and target for cancer therapy. Transforming growth factor-β (TGFβ) induces the expression of this plasma membrane protein specifically in aggressive and treatment resistant tumor cells derived from mesenchymal stem cells, with minimal expression observed in non-neoplastic tissues. We have developed a humanized monocl
INTRODUCTION: Maternal blood pressure (BP) is crucial for the health of both mother and fetus, with long-term implications for the child's health. Studies exploring the link between perfluoroalkyl substances (PFAS) exposure and hypertensive disorders of pregnancy often yield inconsistent results, frequently focusing on a single BP measurement rather than longitudinal measurements. This study chara
Solar-driven hydrogen production stores renewable energy chemically but suffers from efficiency limitations due to the slow hole transport-dominated recombination, which caused by high valence band degeneracy and hole effective mass. Targeted hole trap regulation is essential to minimize these losses and enhance photocatalytic H2 evolution performance for practical applications. This study address
Background: The eco-corona, consisting of environmental biomolecules formed around engineered nanomaterials (ENMs) when released to the environment, has gained increasing focus in the scientific literature and its role for ENM fate and toxicity is now widely acknowledged. The European chemicals legislation, REACH, entails reporting requirements when it comes to the transformation of nanoforms. Gui
Perovskites have attracted widespread attention for laser applications due to their excellent optoelectronic properties. However, perovskite lasers typically exhibit a wavelength shift as pump density increases. Here, we report a pump-induced wavelength shift-free laser achieved using a perovskite nanoplatelet with mixed orthorhombic and tetragonal phase. At 293 K, the tetragonal-phase perovskite
Empiric combination antibiotic therapy (ECAT) is commonly used to treat healthcare-associated bloodstream infections (HA-BSIs) and sepsis. However, the level of supporting evidence is low and clinical practice varies significantly. We conducted a post hoc analysis using the EUROBACT-2 international cohort study database, which contained data on 2406 adult patients from 328 intensive care units (IC
