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Inhalation administration of therapeutics is a crucial method for treatment of respiratory diseases, offering direct access to the target organ. However, the progression of candidate drugs is frequently impacted by clinical dose level limitations due to lung histopathological findings or functional effects identified in in vivo studies. Addressing these safety concerns is crucial in advancing comp
Studio recordings of music for English bass horn and string trio from the composers Louis Massonneau, Emma Jane Lloyd, and Ylva Lund Bergner, recorded at the St Cecilia's Hall in Edinburgh on 17 January 2026.
This is a scoping review of low-intensity, home-based interventions promoting learning for 11–17-year-olds in foster care. Research shows that children in out-of-home care fall behind in school compared to their peers. Interventions to improve learning outcomes for these children typically i) target young children or children aging out of care, and ii) require many resources to implement. Lo
Designing composite photocatalytic systems with nanoscale precision is crucial. While conventional facet-selective photo-deposition successfully utilizes spherical co-catalysts, the directed deposition of pre-synthesized two-dimensional (2D) materials onto specific facets remains extremely challenging. This work demonstrates an electrostatic assembly strategy for the precise deposition of 2D trans
Obesity is a stigmatized disease due to pervasive personal, professional, institutional, and cultural weight bias. Individuals with obesity experience weight bias across their lifespan and settings, which can affect their life chances and significantly impact health and social outcomes. The objectives of this study were to: (a) explore weight bias and stigma experiences of people living with obesi
Winter is a critical bottleneck period for many insects and is particularly pivotal for pest species, being a major regulator of their populations. In winter, insect fruit pests such as the invasive fly, Drosophila suzukii, not only have to cope with harsh environmental conditions but also need to find alternative resources when cultivated fruit are scarce. This study aimed to disentangle the rela
Despite being subject to a multitude of investigations, the effect of carrier particle size on the performance of adhesive mixtures for inhalation is still not well understood. This study, involving three differently sized lactose carriers, all with the regular ‘tomahawk’ particle shape, aims to provide fundamental insight into this topic. Fine particle fraction (FPF) data for binary formulations
Unilateral neck exploration for primary hyperparathyroidism (pHPT) of old and high risk patients can be safely performed under local anesthesia, provided there is a correct preoperative side localization of the enlarged parathyroid gland. We performed large vein sampling and measured intact parathyroid hormones (PTH) with a new, highly sensitive immunoradiometric assay. The method was used before
Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. Its bio-based origin, biodegradability an
We consider the Dirichlet-Neumann iteration for partitioned simulation of thermal fluid-structure interaction, also called conjugate heat transfer. We analyze its convergence rate for two coupled fully discretized 1D linear heat equations with jumps in the material coefficients across these. These are discretized using implicit Euler in time, a finite element method on one domain, a finite volume
Popular Science AbstractHow well bees can see the world?aBees such as bumblebees and honeybees are some of the most important pollinators. They pollinate by using different sensory cues from the flowers, primarily vision and olfaction. In my PhD I was interested in understanding how well bees can see while they are inspecting flowers as well as while they are performing high-speed flight maneuversBees use multiple sensory modalities to perform day-to-day tasks. Light allows them to perceive objects and the general features of their surroundings, enabling them to find food and to navigate safely across the landscape. Although both these tasks involve vision, the requirements of the visual system differ depending upon what the bee wants to achieve; locate a flower to feed from or adjust its
Families living with mental illness express needs of support and experiences of burden that may affect their own health detrimentally and hence also their ability to support the patient. Mindfulness-based interventions have shown beneficial health effects in both clinical and healthy populations. The aim of the current study was to explore the effectiveness and usability of a web-based mindfulness
The purpose of this study was to explore the feasibility of developing artificial neural networks that are able to provide confidence measures for their diagnostic advice. Computer-aided decision making can improve physician performance, but many physicians hesitate to use these 'black boxes'. If we are to rely upon decision support systems for such tasks as medical diagnosis it is essential that
The recording and verbatim transcription of interviews is often considered to be one of the more tedious but necessary aspects of the in-depth qualitative research process. While transcription is undoubtedly a necessary methodological tool for researchers focusing specifically on discourse and language, it has also been widely adopted by researchers across the social sciences, and is sometimes adv
Aims and objectives: To explore healthcare professionals' conceptions of caring for sick children in home care services. Background: Families often prefer home care to hospital care, and the number of home care services for children is increasing. Caring for children at home has been recognised as challenging for healthcare professionals in home care services used to providing care predominately f
Newton-Raphson and Goldschmidt algorithms can be sped up by using variable latency hardware architectures for rounding division, square root and their reciprocals. A new approach based on a rounding method with remainder estimate calculated concurrently with the algorithm was proposed in [5]. This paper presents an study of the hardware implementation of this approach and shows that does not suppo
Expression microarray analysis identified over 930 genes regulated during puberty in the mouse mammary gland. Most prominent were genes whose expression increased in parallel with pubertal development and remained high thereafter. Members of the Wnt, transforming growth factor-beta and oestrogen-signalling pathways were significantly overrepresented. Comparison to expression data from CITED1 knock
