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Accumulating evidence suggests that a compromised intestinal epithelial barrier (IEB) contributes to the progression of metabolic dysfunction-associated steatotic liver disease (MASLD); however, the exact mechanisms remain unclear. Here we reveal that intestinal mucin 1 (MUC1) levels and glycosylation are decreased in both humans and male mice with MASLD. Enterocyte-specific Muc1 knockout aggravat

The present study aimed to increase understanding of how singing activities may be initiated in primary school, and what support and assistance teachers require to conduct singing activities as an integrated part of the school day. Five music teachers participated in a focus group interview. The following main themes were identified: 1) pedagogical and methodological flexibility, 2) the role of ro

Out-of-pocket (OOP) expenditures for childbirth in Bangladesh have increased substantially, intensifying financial pressure on lower-income households. While wealthier groups historically bore higher delivery costs, recent trends indicate a narrowing gap in spending across socioeconomic strata. This study investigates the drivers of this convergence in delivery-related expenditures between 2014 an

BackgroundWomen’s empowerment may influence non-communicable disease (NCD) risk. However, evidence on these associations among women in Bangladesh remains limited. This study examined the associations between women’s empowerment and the prevalence of selected non-communicable conditions among ever-married reproductive-aged women in Bangladesh.MethodsData from the 2022 Bangladesh Demographic and He

BACKGROUND: Accreditation of cancer centres aims to deliver high-quality, person-centered care and underscores the integration with education, research, and innovation. Over the past decade, cancer centres in the Nordic countries have engaged in accreditation processes through the Organisation of European Cancer Institutes (OECI).OBJECTIVE: This study provides an overview of a rapidly evolving lan

Nucleotides and coenzymes play critical roles in energy metabolism and cellular signaling and as building blocks of nucleic acids. This work addresses the challenges in the measurement of the phosphorylated metabolites using hydrophilic interaction liquid chromatography coupled with mass spectrometry, which facilitates the separation and detection of polar metabolites. Here, we present optimized H

Background and aims: We examined whether the excess cardiovascular disease (CVD) risk among adults with steatotic liver disease (SLD) subtypes could be reduced or eliminated through joint control of low-density lipoprotein cholesterol (LDL-C), lipoprotein(a) [Lp(a)], and high-sensitivity C-reactive protein (hs-CRP). Methods and results: This prospective cohort study included 291,995 participants f

Early-life adversity negatively affects morbidity and survival in late life, but knowledge is limited about effects on women’s reproduction and reproductive health. To deepen our understanding of the full effects of disease exposure in early life, including long-term consequences, we study women’s reproductive outcomes and their offspring’s health. Using the Scanian Economic Demographic Database a

Bacteriophages exert strong selective pressure on bacterial populations and play a central role in shaping microbial evolution. In response to phage predation, bacteria have evolved diverse antiphage defence mechanisms that interfere with viral replication through a wide range of molecular strategies. Recent genomic studies have revealed a rapidly expanding repertoire of candidate defence systems,

Abstract INTRODUCTION Countries have varying, limited healthcare budgets for emerging disease-modifying therapies. Cost-effectiveness analysis, combined with country-level cost-effectiveness thresholds, can be used to estimate value-based prices (VBPs) for lecanemab and donanemab across 174 countries. METHODS The cost-effectiveness of lecanemab and donanemab was estimated using incremental cost an

BACKGROUND: Weight-adjusted-waist index (WWI) is an anthropometric index reflecting fat mass and muscle mass, both of which are important factors influencing insulin resistance and inflammation.OBJECTIVES: We aimed to examine the associations of WWI with all-cause, cardiovascular, and noncardiovascular mortality among individuals with type 2 diabetes (T2D) and further investigate whether insulin r

Heavy metals are toxic elements that can have significant adverse effects on human health, particularly during vulnerable periods such as pregnancy. The presence of heavy metals in the environment can lead to increased exposure in pregnant women, which may adversely affect both maternal and neonatal health. This study investigates the relationship between heavy metal concentrations, thyroid hormon

Prostate cancer (PCa) incidence has steadily increased in Sweden, more steeply in the mid-1990s caused by increased opportunistic prostate-specific antigen (PSA) testing. Tallness, normal weight, and non-smoking are associated with more PSA testing, which increases detection of low-risk and localised PCa. We investigated time trends of height, body mass index (BMI), and smoking with PCa risk in 17

Aims: Social science literature suggests that unlimited trust in others may lead to adverse outcomes, and that moderate trust may be more optimal in social interactions. The aim was to analyze associations between generalized trust in other people and all-cause mortality using a four-alternative generalized trust item that includes moderate trust. Study design: Prospective cohort study. Methods: T

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Microsoft Word - 20181002_schema_inspirationskonf_HT HT‐fakulteternas inspirationskonferens, torsdagen den 8 november 2018  Tid  Aktivitet  08.30‐09‐00  LUX Aula övre  Registrering  09.00‐09.10  LUX Aula övre  Välkomsthälsning av prodekan Ann‐Kristin Wallengren  09.10‐10.00  LUX Aula övre  Keynoteföreläsning: Kollegialitet i akademiska lärmiljöer  Katarina Mårtensson (AHU) och Torgny Roxå (Genombr

https://konferens.ht.lu.se/fileadmin/user_upload/conference/insp18/20181022_schema_inspirationskonf_HT.pdf - 2026-05-18

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2 Հրաժարագիր Սույն ուղեցույցում արտահայտված կարծիքները պատկանում են հեղինակ(ներ)ին և պարտադիր չէ, որ արտահայտեն Շվեդական ինստիտուտի, Շրջակա միջավայրի, գյուղատնտեսական գիտությունների և տարածական պլանավորման շվեդական հետազոտական խորհրդի («Formas») կամ «Biodiversa+» կազմակերպության պաշտոնական տեսակետները: Խնդրում ենք նկատի առնել, որ սույն փաստաթուղթը իրավական խորհրդատվություն կամ իրավական փաստաթղթերի

https://rwi.lu.se/wp-content/uploads/2025/11/Model-Guidelines_ARM_Print_V2.pdf - 2026-05-18